en-usCOVID-19, is particularly threatening to patients with kidney disease and to their caregivers. JASN, CJASN, and Kidney360 are sharing valid, peer reviewed information as quickly as possible. This collection of COVID-19 articles is updated with new <b>Original Research, Brief/Rapid Communication, Clinical Research, Original Investigations and Research Letter articles</b> as soon as they are published. <p></p><p></p> <p> </p> A second collection, <a href="https://asnjournals.org/cc/covid-19-in-context"> COVID-19: In Context </a> is also available. It contains Perspectives, Editorials, Letters to the Editor, Kidney Case Conference and more. <p></p> <p></p> More resources on COVID-19 can be found on the ASN COVID-19 page: <a href="https://www.asn-online.org/covid-19">ASN COVID-19 Resources</a><p></p> <b> Related Information: </b><p></p><p></p> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/12/article-p25_16.xml?WT.mc_id=CC">COVID-19 Wellness Module Offered through ASN Website</a> (ASN <i>Kidney News</i>)</li> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/10/11/article-p47_27.xml?WT.mc_id=CC">The ASN COVID-19 Response Team: Finding the Silver Lining</a> (ASN <i>Kidney News)</i>)</li> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/9/article-p23_12.xml?WT.mc_id=CC">SARS-CoV-2 Vaccinations in Transplant Recipients: The More the Better </a>(ASN <i>Kidney News</i>)</li> <b>Podcasts</b> <li><a href="https://www.asn-online.org/media/podcast/CJASN/2021_07_09_CJN17311120.mp3"> CJASN Podcast: Predictive Approaches for Acute Dialysis Requirement and Death in COVID-19</a> </li><li><a href="https://www.asn-online.org/media/podcast/JASN/2021_07_07_JASN2021010104.mp3"> JASN Podcast: Vaccine Acceptability and Hemodialysis Patients </a> </li><li><a href="https://www.asn-online.org/media/podcast/JASN/2021_06_11_JASN2021040536B.mp3"> JASN Podcast: COVID-19 Mortality and the Tough Discussions about Advance Care Planning</a> </li><li><a href="https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/K360/2020_11_25_KID0003962020.mp3"> Kidney360 Podcast: Characteristics, Outcomes &amp; 60-Day Hospital Mortality of ICU Patients with COVID-19 &amp; Acute Kidney Injury</a> </li><li><a href="https://www.asn-online.org/media/podcast/CJASN/2020_11_16_CJN09610620_final.mp3"> CJASN Podcast: Acute Kidney Injury in a National Cohort of Hospitalized US Veterans with COVID-19</a> </li>Thu, 25 Apr 2024 08:20:21 GMThttp://cct.highwire.org/feeds/asn/covid-19.rssBackground:Cases of de novo glomerular disease with various renal histologies have been reported after vaccination against SARS-CoV-2. Causality has not been established and the long-term outcomes are not known. To better characterize the glomerular diseases and clinical course/outcomes, we created the International Registry of COVID-19 vaccination and Glomerulonephritis (IRocGN2) to study in aggregate de novo glomerulonephritis cases suspected after COVID-19 vaccine exposure Methods:A RedCap survey was used for anonymized data collection. Detailed information on vaccination type and timing and glomerular disease histology were recorded in the registry. We collected serial information on laboratory values (before and after vaccination and during follow-up), treatments, and kidney-related outcomes. Results: Ninety-eight glomerular disease cases were entered into the registry over eleven months from 44 centers throughout the world. Median follow-up was 89 days after diagnosis. IgA nephropathy (IgAN) and minimal change disease (MCD) were the most the common kidney diseases reported. Recovery of kidney function and remission of proteinuria was more likely in IgAN and MCD at 4-6 months than with pauci immune glomerulonephritis /vasculitis and membranous nephropathy. Conclusions:Development of glomerular disease after vaccination against SARS-CoV-2 may be a very rare adverse event. Temporal association is present for IgAN and MCD, but causality is not firmly established. Kidney outcomes for IgAN and MCD are favorable. No changes in vaccination risk-benefit assessment is recommended based on these findings.waldmanm@niddk.nih.gov10.34067/KID.0006832022Fri, 16 Dec 2022 03:21:56 GMT-08:00COVID-19 Vaccination and new onset glomerular disease: Results from the IRocGN2 International registryBackground:Cases of de novo glomerular disease with various renal histologies have been reported after vaccination against SARS-CoV-2. Causality has not been established and the long-term outcomes are not known. To better characterize the glomerular diseases and clinical course/outcomes, we created the International Registry of COVID-19 vaccination and Glomerulonephritis (IRocGN2) to study in aggregate de novo glomerulonephritis cases suspected after COVID-19 vaccine exposure Methods:A RedCap survey was used for anonymized data collection. Detailed information on vaccination type and timing and glomerular disease histology were recorded in the registry. We collected serial information on laboratory values (before and after vaccination and during follow-up), treatments, and kidney-related outcomes. Results: Ninety-eight glomerular disease cases were entered into the registry over eleven months from 44 centers throughout the world. Median follow-up was 89 days after diagnosis. IgA nephropathy (IgAN) and minimal change disease (MCD) were the most the common kidney diseases reported. Recovery of kidney function and remission of proteinuria was more likely in IgAN and MCD at 4-6 months than with pauci immune glomerulonephritis /vasculitis and membranous nephropathy. Conclusions:Development of glomerular disease after vaccination against SARS-CoV-2 may be a very rare adverse event. Temporal association is present for IgAN and MCD, but causality is not firmly established. Kidney outcomes for IgAN and MCD are favorable. No changes in vaccination risk-benefit assessment is recommended based on these findings.Waldman, MerylSinaii, NinetLerma, Edgar V.Kurien, Anila AbrahamJhaveri, Kenar D.Uppal, Nupur N.Wanchoo, RimdaAvasare, RupaliZuckerman, Jonathan E.Liew, AdrianGallan, Alexander J.El-Meanawy, AshrafYagil, YoramLebedev, LarissaBaskaran, KrishobanVilayur, EswariWai Seung, AdrienneWeerasinghe, NethmiPetrakis, IoannisStylianou, KostasGakiopoulou, HarikleiaHamilton, Alexander J.Edney, NaomiMillner, RachelMarinaki, SmaragdiRein, Joshua L.Killen, John PaulRodríguez Chagolla, Jose ManuelBassil, ClaudeLopez del Valle, RamonEvans, JordanUrisman, AnatolyZawaideh, MonaBaxi, Pravir V.Rodby, Roger A.Vankalakunti, MaheshaMejia Vilet, Juan M.Ramirez Andrade, Silvia EuniceHoman, MalVasquez Jimenez, EnzoPerinpanayagam, NatashaVelez, Juan Carlos Q.Mohamed, Muner M.B.Mohammed, Khalid M.GSekar, ArjunOllila, LauraAron, Abraham WArellano Arteaga, Kevin JavierIslam, MahmudBerrio, Esperanza MoralMaoujoud, OmarMorales, Rebecca RufSeipp, ReganSchulze, Carl E.Yenchek, Robert H.Vancea, IrinaMuneeb, MuhammadHoward, LilianCaza, Tiffany N.2022-12-16T15:21:56-08:00doi:10.34067/KID.0006832022hwp:resource-id:kidney360;KID.0006832022v1American Society of NephrologyCopyright © 2022 American Society of NephrologyKidney360covid-19 vaccine, glomerular, kidney, nephrotic, COVID-19, Registries, IRocGN2Original InvestigationOriginal Investigationother202210.34067/KID.00068320222641-76502641-76502022-12-16T15:21:56-08:00Kidney360Original Investigation10.34067/KID.0006832022Background: The COVID-19 pandemic has disrupted health systems and created numerous challenges in hospitals worldwide for patients and healthcare workers (HCWs). Hemodialysis centers are at risk of COVID-19 outbreaks given the difficulty of maintaining social distancing and the fact that hemodialysis patients are at higher risk of being infected with COVID-19. During the COVID-19 pandemic, HCWs have had to face many challenges and stressors. Our study was designed to gain HCWs' perspectives on their experiences of the impacts of the COVID-19 pandemic in hemodialysis units. Methods: Semi-structured interviews were conducted with 22 HCWs (nurses, nephrologists, pharmacists, social workers, patient attendants, security agents) working in five hemodialysis centers in Montreal, between November 2020 and May 2021. The content of the interviews was analyzed using thematic analysis. Results: Four themes were identified during the interviews. The first was the impact of COVID-19 on work organization, regarding which participants reported an increased workload, a need for a consistent information strategy, and positive innovations such as telemedicine. The second theme was challenges associated with communicating and caring for dialysis patients during the pandemic. The third theme was psychological distress experienced by hemodialysis staff and the psychosocial impact of COVID-19 on their personal lives. The fourth theme was recommendations made by participants for future public health emergencies, such as maintaining public health measures, ensuring an adequate supply of protective equipment and developing a consistent communication strategy. Conclusions: During the first and second waves of the COVID-19 pandemic, HCWs working in hemodialysis units faced multiple challenges that impacted their wellbeing and their work. In order to minimize challenges for HCWs in hemodialysis during a future pandemic, the healthcare system should provide an adequate supply of protective equipment, develop effective communication strategies and take into account the psychological distress related to HCWs' professional and personal lives.marie-chantal.fortin.med@ssss.gouv.qc.ca10.34067/KID.0004252022Tue, 13 Dec 2022 01:29:47 GMT-08:00Lived experiences of hemodialysis healthcare workers during the COVID-19 pandemic: A qualitative study from the Quebec Renal NetworkBackground: The COVID-19 pandemic has disrupted health systems and created numerous challenges in hospitals worldwide for patients and healthcare workers (HCWs). Hemodialysis centers are at risk of COVID-19 outbreaks given the difficulty of maintaining social distancing and the fact that hemodialysis patients are at higher risk of being infected with COVID-19. During the COVID-19 pandemic, HCWs have had to face many challenges and stressors. Our study was designed to gain HCWs' perspectives on their experiences of the impacts of the COVID-19 pandemic in hemodialysis units. Methods: Semi-structured interviews were conducted with 22 HCWs (nurses, nephrologists, pharmacists, social workers, patient attendants, security agents) working in five hemodialysis centers in Montreal, between November 2020 and May 2021. The content of the interviews was analyzed using thematic analysis. Results: Four themes were identified during the interviews. The first was the impact of COVID-19 on work organization, regarding which participants reported an increased workload, a need for a consistent information strategy, and positive innovations such as telemedicine. The second theme was challenges associated with communicating and caring for dialysis patients during the pandemic. The third theme was psychological distress experienced by hemodialysis staff and the psychosocial impact of COVID-19 on their personal lives. The fourth theme was recommendations made by participants for future public health emergencies, such as maintaining public health measures, ensuring an adequate supply of protective equipment and developing a consistent communication strategy. Conclusions: During the first and second waves of the COVID-19 pandemic, HCWs working in hemodialysis units faced multiple challenges that impacted their wellbeing and their work. In order to minimize challenges for HCWs in hemodialysis during a future pandemic, the healthcare system should provide an adequate supply of protective equipment, develop effective communication strategies and take into account the psychological distress related to HCWs' professional and personal lives.Affdal, AliyaMalo, Marie-FrançoiseBlum, DanielBallesteros Gallego, FabianBeaubien-Souligny, WilliamCaron, Marie-LineNadeau-Fredette, Annie-ClaireVasilevsky, MurrayRios, NorkaSuri, Rita S.Fortin, Marie-Chantal2022-12-13T13:29:47-08:00doi:10.34067/KID.0004252022hwp:resource-id:kidney360;KID.0004252022v1American Society of NephrologyCopyright © 2022 American Society of NephrologyKidney360hemodialysis, healthcare providers, COVID-19 pandemic, Qualitative study, Semi-directed interviewsOriginal InvestigationOriginal Investigationother202210.34067/KID.00042520222641-76502641-76502022-12-13T13:29:47-08:00Kidney360Original Investigation10.34067/KID.000425202210.1681/ASN.2022030258Fri, 04 Nov 2022 01:16:32 GMT-07:00A Population-Based Analysis of the Risk of Glomerular Disease Relapse after COVID-19 VaccinationCanney, MarkAtiquzzaman, MohammadCunningham, Amanda M.Zheng, YuyanEr, LeeHawken, StevenZhao, YinshanBarbour, Sean J.2022-11-04T13:16:32-07:00doi:10.1681/ASN.2022030258hwp:resource-id:jnephrol;33/12/2247American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical epidemiology, glomerular disease, COVID-19, vaccination, recurrence, glomerulonephritisClinical EpidemiologyGlomerulonephritis and Interstitial NephritisClinical EpidemiologyGlomerulonephritis and Interstitial Nephritisresearch-article20222022-12-01December 202210.1681/ASN.20220302581046-66731533-34502022-11-04T13:16:32-07:002022-12Journal of the American Society of NephrologyClinical Epidemiology331212224721282257213110.1681/ASN.2022091078Fri, 04 Nov 2022 01:16:32 GMT-07:00mRNA COVID-19 Vaccines and Their Risk to Induce a Relapse of Glomerular DiseasesKronbichler, AndreasAnders, Hans-Joachim2022-11-04T13:16:32-07:00doi:10.1681/ASN.2022091078hwp:resource-id:jnephrol;33/12/2128American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyglomerular disease, vasculitis, IgA nephropathy, lupus nephritis, focal segmental glomerulosclerosis, membranous nephropathy, COVID-19Up Front MattersEditorialUp Front MattersEditorialeditorial20222022-12-01December 202210.1681/ASN.20220910781046-66731533-34502022-11-04T13:16:32-07:002022-12Journal of the American Society of NephrologyUp Front Matters331212212822472131225710.34067/KID.0003092022Tue, 20 Sep 2022 07:33:25 GMT-07:00SARS-CoV-2 Infections among Vaccinated Patients on Maintenance Dialysis, January 1–August 31, 2021, United StatesBardossy, Ana CeciliaAngeles, JeseniaBooth, StephanieFike, LucyWadley, AshleyRha, BrianLacson, EduardoManley, Harold J.Johnson, DougApata, Ibironke W.Novosad, Shannon2022-09-20T07:33:25-07:00doi:10.34067/KID.0003092022hwp:resource-id:kidney360;3/11/1934American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, COVID-19, COVID-19 vaccine, end stage renal disease, ESKD, SARS-CoV-2, United StatesBrief CommunicationDialysisBrief CommunicationDialysisresearch-article20222022-11-2410.34067/KID.00030920222641-76502022-09-20T07:33:25-07:002022-11-24Kidney360Brief Communication3111934193810.1681/ASN.2022010125Tue, 30 Aug 2022 07:22:48 GMT-07:00Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to SeveritySun, ZeguoZhang, ZhongyangBanu, KhadijaAzzi, Yorg AlReghuvaran, AnandFredericks, SamuelPlanoutene, MarinaHartzell, SusanKim, YeslPell, JohnTietjen, GregoryAsch, WilliamKulkarni, SanjayFormica, RichardRana, MeenakshiMaltzman, Jonathan S.Zhang, WeijiaAkalin, EnverHeeger, Peter S.Cravedi, PaoloMenon, Madhav C.2022-08-30T07:22:48-07:00doi:10.1681/ASN.2022010125hwp:resource-id:jnephrol;33/11/2108American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, COVID-19, immune deficiency, SARS-CoV-2, transcriptomeClinical ResearchTransplantationClinical ResearchTransplantationresearch-article20222022-11-01November 202210.1681/ASN.20220101251046-66731533-34502022-08-30T07:22:48-07:002022-11Journal of the American Society of NephrologyClinical Research33112108212210.34067/KID.0002542022Wed, 10 Aug 2022 01:41:42 GMT-07:00Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis PatientsValentini, NicolasMarchitto, LorieRaymond, MaximeGoyette, GuillaumeKaufmann, Daniel E.Finzi, AndrésSuri, Rita S.Lamarche, Caroline2022-08-10T13:41:42-07:00doi:10.34067/KID.0002542022hwp:resource-id:kidney360;3/10/1763American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360chronic kidney disease, basic science, COVID-19, dendritic cell, immune response, innate immunity, monocyte, mRNA vaccine, SARS-CoV-2Brief CommunicationChronic Kidney DiseaseBrief CommunicationChronic Kidney Diseaserapid-communication20222022-10-2710.34067/KID.00025420222641-76502022-08-10T13:41:42-07:002022-10-27Kidney360Brief Communication3101763176810.34067/KID.0004062022Mon, 15 Aug 2022 01:52:02 GMT-07:00International Practices on COVID-19 Vaccine Mandates for Transplant CandidatesCaliskan, YasarHippen, Benjamin E.Axelrod, David A.Schnitzler, MarkMaher, KennanAlhamad, TarekLam, Ngan N.Anwar, SiddiqKute, VivekLentine, Krista L.2022-08-15T13:52:02-07:00doi:10.34067/KID.0004062022hwp:resource-id:kidney360;3/10/1754American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, COVID-19, international practices, patient safety, solid organ transplantation, vaccines, waitlist managementOriginal InvestigationTransplantationOriginal InvestigationTransplantationresearch-article20222022-10-2710.34067/KID.00040620222641-76502022-08-15T13:52:02-07:002022-10-27Kidney360Original Investigation31017541762Background: The kidney biopsy is the gold standard for the diagnosis of glomerular diseases. Large-scale, epidemiological studies describing the prevalence of kidney diseases are lacking especially in the US. We aimed to determine the spectrum of biopsy proven kidney disease across the Cleveland Clinic enterprise. Methods: We identified all patients with a native kidney biopsy performed/reviewed at the Cleveland Clinic from January 2015 to September 2021. Retrospective chart review was performed to obtain clinical and demographic characteristics. Results were stratified by age, gender, race and location to determine epidemiological trends. Results: Of over 9600 patients, we excluded transplant/donor biopsies and unavailable records, and included 4128 patients with native kidney biopsy data. The median age was 60 years, with 46.2% female patients. Self-reported racial demographics included 72.9% White, 21.7% Black, 3.1% multi-racial, and 1.6% Asian background, with 5.1% Hispanic. Common diagnoses were: FSGS (n=633, 15.3%), diabetic kidney disease (DKD) (n=602, 14.6%), IgA nephropathy (n=319, 7.7%), lupus nephritis (LN) (n=289, 7.0%), pauci-immune glomerulonephritis (n=275, 6.7%), membranous nephropathy (n=211, 5.1%), and amyloidosis (n=110, 2.7%). There were 3322 patients in Ohio, with 361 patients in Florida. Using multivariate analysis, those over 70 years were more likely to have FSGS, while those less than 45 years were more likely to have IgA Nephropathy or LN. Males were more likely to have FSGS or IgAN and less likely to have LN. Blacks were more likely to have FSGS, DKD or LN. Hispanics were more likely to have DKD. Finally, patients in Florida were more likely to have LN. There was no change in the disease spectrum prior to and during the COVID 19 pandemic. Conclusion: Our study catalogues the spectrum of biopsy proven kidney disease across the Cleveland Clinic enterprise. This lays the foundation for glomerular disease clinical trials and highlights the need for a standardized national kidney biopsy registry to bolster glomerular and kidney disease research in the United States.bobarts@ccf.org10.34067/KID.0005882022Wed, 19 Oct 2022 04:33:59 GMT-07:00The Cleveland Clinic Kidney Biopsy Epidemiological ProjectBackground: The kidney biopsy is the gold standard for the diagnosis of glomerular diseases. Large-scale, epidemiological studies describing the prevalence of kidney diseases are lacking especially in the US. We aimed to determine the spectrum of biopsy proven kidney disease across the Cleveland Clinic enterprise. Methods: We identified all patients with a native kidney biopsy performed/reviewed at the Cleveland Clinic from January 2015 to September 2021. Retrospective chart review was performed to obtain clinical and demographic characteristics. Results were stratified by age, gender, race and location to determine epidemiological trends. Results: Of over 9600 patients, we excluded transplant/donor biopsies and unavailable records, and included 4128 patients with native kidney biopsy data. The median age was 60 years, with 46.2% female patients. Self-reported racial demographics included 72.9% White, 21.7% Black, 3.1% multi-racial, and 1.6% Asian background, with 5.1% Hispanic. Common diagnoses were: FSGS (n=633, 15.3%), diabetic kidney disease (DKD) (n=602, 14.6%), IgA nephropathy (n=319, 7.7%), lupus nephritis (LN) (n=289, 7.0%), pauci-immune glomerulonephritis (n=275, 6.7%), membranous nephropathy (n=211, 5.1%), and amyloidosis (n=110, 2.7%). There were 3322 patients in Ohio, with 361 patients in Florida. Using multivariate analysis, those over 70 years were more likely to have FSGS, while those less than 45 years were more likely to have IgA Nephropathy or LN. Males were more likely to have FSGS or IgAN and less likely to have LN. Blacks were more likely to have FSGS, DKD or LN. Hispanics were more likely to have DKD. Finally, patients in Florida were more likely to have LN. There was no change in the disease spectrum prior to and during the COVID 19 pandemic. Conclusion: Our study catalogues the spectrum of biopsy proven kidney disease across the Cleveland Clinic enterprise. This lays the foundation for glomerular disease clinical trials and highlights the need for a standardized national kidney biopsy registry to bolster glomerular and kidney disease research in the United States.Bobart, Shane A.Portalatin, GildaSawaf, HannyShettigar, ShrutiCarrion Rodriguez, AstridLiang, HongHerlitz, LealGebreselassie, Surafel K.2022-10-19T04:33:59-07:00doi:10.34067/KID.0005882022hwp:resource-id:kidney360;KID.0005882022v1American Society of NephrologyCopyright © 2022 American Society of NephrologyKidney360Kidney Biopsy, Glomerular Disease, Diabetes, FSGS, IgA Nephropathy, Lupus Nephritis, Registry, Database, Epidemiology, GlomerulonephritisOriginal InvestigationOriginal Investigationother202210.34067/KID.00058820222641-76502641-76502022-10-19T04:33:59-07:00Kidney360Original Investigation3312122077207710.34067/KID.000588202220852085How maintenance dialysis modality, dialysis setting, and residence in a nursing facility have jointly associated with coronavirus disease 2019 (COVID-19)-related outcomes in the United States is relevant to future viral outbreaks. Using Medicare claims, we determined the incidence of COVID-19–related infection, hospitalization, and death between March 15, 2020 and June 5, 2021. The exposure was one of five combinations of dialysis modality and care setting: in-facility hemodialysis without a recent history of skilled nursing facility care, in-facility hemodialysis with a recent history of skilled nursing facility care, hemodialysis in a skilled nursing facility, home hemodialysis, and (home) peritoneal dialysis. Patient-weeks were pooled to estimate the adjusted associations of event incidence with each dialysis modality/setting during four intervals in 2020–2021. Relative to in-facility hemodialysis without a recent history of skilled nursing facility care, home dialysis was associated with 36%–60% lower odds of all events during weeks 12–23 of 2020; 24%–37% lower odds of all events during weeks 24–37 of 2020; 20%–33% lower odds of infection and hospitalization during the winter of 2020–2021; and similar odds of all events thereafter. In contrast, exposure to skilled nursing facilities was associated with 570%–1140% higher odds of all events during spring of 2020, although excess risk attenuated as the pandemic transpired, especially among patients who received hemodialysis in skilled nursing facilities. In conclusion, home dialysis was associated with lower risks of COVID-19 diagnosis, hospitalization, and death until vaccines were available, whereas care in skilled nursing facilities was associated with higher risks.10.2215/CJN.03400322Thu, 08 Sep 2022 08:07:15 GMT-07:00Associations of COVID-19 Outcomes with Dialysis Modalities and SettingsHow maintenance dialysis modality, dialysis setting, and residence in a nursing facility have jointly associated with coronavirus disease 2019 (COVID-19)-related outcomes in the United States is relevant to future viral outbreaks. Using Medicare claims, we determined the incidence of COVID-19–related infection, hospitalization, and death between March 15, 2020 and June 5, 2021. The exposure was one of five combinations of dialysis modality and care setting: in-facility hemodialysis without a recent history of skilled nursing facility care, in-facility hemodialysis with a recent history of skilled nursing facility care, hemodialysis in a skilled nursing facility, home hemodialysis, and (home) peritoneal dialysis. Patient-weeks were pooled to estimate the adjusted associations of event incidence with each dialysis modality/setting during four intervals in 2020–2021. Relative to in-facility hemodialysis without a recent history of skilled nursing facility care, home dialysis was associated with 36%–60% lower odds of all events during weeks 12–23 of 2020; 24%–37% lower odds of all events during weeks 24–37 of 2020; 20%–33% lower odds of infection and hospitalization during the winter of 2020–2021; and similar odds of all events thereafter. In contrast, exposure to skilled nursing facilities was associated with 570%–1140% higher odds of all events during spring of 2020, although excess risk attenuated as the pandemic transpired, especially among patients who received hemodialysis in skilled nursing facilities. In conclusion, home dialysis was associated with lower risks of COVID-19 diagnosis, hospitalization, and death until vaccines were available, whereas care in skilled nursing facilities was associated with higher risks.Weinhandl, Eric D.Liu, JiannongGilbertson, David T.Wetmore, James B.Johansen, Kirsten L.2022-09-08T08:07:15-07:00doi:10.2215/CJN.03400322hwp:resource-id:clinjasn;17/10/1526American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States Renal Data System, COVID-19, ESRDInsights from the USRDSInsights from the USRDSresearch-article20222022-10-01October 202210.2215/CJN.034003221555-90411555-905X2022-09-08T08:07:15-07:002022-10Clinical Journal of the American Society of NephrologyInsights from the USRDS17101526153410.1681/ASN.2022040504Tue, 16 Aug 2022 07:40:22 GMT-07:00SARS-CoV-2 Infection during the Omicron Surge among Patients Receiving Dialysis: The Role of Circulating Receptor-Binding Domain Antibodies and Vaccine DosesMontez-Rath, Maria E.Garcia, PabloHan, JialinCadden, LinaCelHunsader, PattiMorgan, CurtKerschmann, RussellBeyer, PaulDittrich, MaryBlock, Geoffrey A.Parsonnet, JulieChertow, Glenn M.Anand, Shuchi2022-08-16T07:40:22-07:00doi:10.1681/ASN.2022040504hwp:resource-id:jnephrol;33/10/1832American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologychronic dialysis, ESKD, immunology, clinical epidemiology, COVID-19, SARS-CoV-2Rapid CommunicationGlomerulonephritis and Interstitial NephritisRapid CommunicationGlomerulonephritis and Interstitial Nephritisresearch-article20222022-10-01October 202210.1681/ASN.20220405041046-66731533-34502022-08-16T07:40:22-07:002022-10Journal of the American Society of NephrologyRapid Communication33101832183910.34067/KID.0001632022Wed, 18 May 2022 01:30:25 GMT-07:00Refractoriness of Hyperkalemia and Hyperphosphatemia in Dialysis-Dependent AKI Associated with COVID-19Kanduri, Swetha R.Ramanand, AkankshVarghese, VipinWen, YuangMohamed, Muner M.B.Velez, Juan Carlos Q.2022-05-18T13:30:25-07:00doi:10.34067/KID.0001632022hwp:resource-id:kidney360;3/8/1317American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360clinical nephrology, acute kidney injury, coronavirus, COVID-19, CRRT, electrolyte, hyperkalemia, hyperphosphatemia, phosphorus, potassium, SLEDOriginal InvestigationAcid/Base and Electrolyte DisordersOriginal InvestigationAcid/Base and Electrolyte Disordersresearch-article20222022-08-2510.34067/KID.00016320222641-76502022-05-18T13:30:25-07:002022-08-25Kidney360Original Investigation381317132210.34067/KID.0000222022Wed, 25 May 2022 06:56:49 GMT-07:00Associations of Anxiety during the COVID-19 Pandemic with Patient Characteristics and Behaviors in CKD Patients: Findings from the Chronic Renal Insufficiency Cohort (CRIC) StudyDorans, Kirsten S.Wright Nunes, Julie A.Schaubel, Douglas E.Sha, 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PhilippeFernandez, IgnacioBouvier, MagaliSamson, ChloéDahmane, DjamalRieu, PhilippeNizard, PatriceFourati, SlimSakhi, HamzaMahévas, Matthieu,Audard, VincentBentaarit, BoutheinaBoueilh, AnnaGallien, SébastienGrimbert, PhilippeHue, SophieJoher, NizarJouan, NarindraLamriben, LarbiLelièvre, Jean-DanielLepeule, RaphaëlMahévas, MatthieuMatignon, MarieMelica, GiovannaOniszczuk, JuliePawlotsky, Jean-MichelStehlé, ThomasVindrios, WilliamWemmert, Charlotte2022-06-28T11:05:04-07:00doi:10.2215/CJN.00830122hwp:resource-id:clinjasn;17/7/1008American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, immunology, mRNA vaccine, SARS-CoV-2, COVID-19, memory B cellsOriginal ArticleMaintenance DialysisOriginal ArticleMaintenance Dialysisresearch-article20222022-07-01July 202210.2215/CJN.008301221555-90411555-905X2022-06-28T11:05:04-07:002022-07Clinical Journal of the American Society of NephrologyOriginal 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the American Society of Nephrologyvaccination, COVID-19, clinical epidemiology, dialysis, transplantation, kidney replacement therapyLetter to the EditorLetter to the Editorletter20222022-07-01July 202210.1681/ASN.20220303821046-66731533-34502022-06-21T07:17:29-07:002022-07Journal of the American Society of NephrologyLetter to the Editor33774143014286771431143068610.1681/ASN.2021091209Wed, 02 Mar 2022 09:47:43 GMT-08:00A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 InfectionHassler, LuiseWysocki, JanGelarden, IanSharma, IshaTomatsidou, AnastasiaYe, MinghaoGula, HaleyNicoleascu, VladRandall, GlennPshenychnyi, SergiiKhurram, NigarKanwar, YashpalMissiakas, DominiqueHenkin, JackYeldandi, AnjanaBatlle, Daniel2022-03-02T09:47:43-08:00doi:10.1681/ASN.2021091209hwp:resource-id:jnephrol;33/7/1293American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyvirology, kidney disease, renin angiotensin system, acute renal failure, renal protection, mice, COVID-19, SARS-CoV-2, angiotensin-converting enzyme 2, disease susceptibilityBasic ResearchAcute Kidney InjuryBasic ResearchAcute Kidney Injuryresearch-article20222022-07-01July 202210.1681/ASN.20210912091046-66731533-34502022-03-02T09:47:43-08:002022-07Journal of the American Society of NephrologyBasic Research3371293130710.1681/ASN.2022030300Tue, 21 Jun 2022 07:17:30 GMT-07:00Clinical Studies of Vaccine EfficacyAshby, Damien2022-06-21T07:17:30-07:00doi:10.1681/ASN.2022030300hwp:resource-id:jnephrol;33/7/1428American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologycovid-19, VaccinationLetter to the EditorLetter to the Editorletter20222022-07-01July 202210.1681/ASN.20220303001046-66731533-34502022-06-21T07:17:30-07:002022-07Journal of the American Society of NephrologyLetter to the Editor33774142814306771430143168610.34067/KID.0008392021Thu, 05 May 2022 01:22:35 GMT-07:00Exacerbation of Racial Disparities in Living Donor Kidney Transplantation During the COVID-19 PandemicSingh, NeerajLi, RuixinAlhamad, TarekSchnitzler, Mark A.Mannon, Roslyn B.Doshi, Mona D.Woodside, Kenneth J.Hippen, Benjamin E.Cooper, MatthewSnyder, JonAxelrod, David A.Lentine, Krista L.2022-05-05T13:22:35-07:00doi:10.34067/KID.0008392021hwp:resource-id:kidney360;3/6/1089American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, access, COVID-19, disparities, kidney transplantation, living donor transplantation, SARS-CoV-2Brief CommunicationTransplantationBrief CommunicationTransplantationresearch-article20222022-06-3010.34067/KID.00083920212641-76502022-05-05T13:22:35-07:002022-06-30Kidney360Brief Communication361089109410.34067/KID.0000242022Fri, 15 Apr 2022 01:32:21 GMT-07:00The Impact of COVID-19 on Postdischarge Outcomes for Dialysis 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NephrologyClinical Journal of the American Society of NephrologyCOVID-19, vaccination, anti-Spike, chronic kidney disease, hemodialysis, peritoneal dialysis, kidney transplantation, SARS-CoV-2Research LetterResearch Letterletter20222022-06-01June 202210.2215/CJN.017702221555-90411555-905X2022-05-12T08:19:26-07:002022-06Clinical Journal of the American Society of NephrologyResearch Letter17687287610.2215/CJN.16621221Wed, 01 Jun 2022 11:44:27 GMT-07:00Severity of COVID-19 after Vaccination among Hemodialysis PatientsAshby, Damien R.Caplin, BenCorbett, Richard W.Asgari, ElhamKumar, NicolaSarnowski, AlexanderHull, RichardMakanjuola, DavidCole, NicholasChen, JianNyberg, SofiaMcCafferty, KieranZaman, FaryalCairns, HughSharpe, ClaireBramham, KateMotallebzadeh, RezaAnwari, Kashif JamilSalama, Alan D.Banerjee, Debasish,Ashby, Damien R.Caplin, BenCorbett, Richard W.Asgari, ElhamKumar, NicolaSarnowski, AlexanderHull, RichardMakanjuola, DavidCole, NicholasChen, JianNyberg, SofiaMcCafferty, 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of Nephrologyclinical epidemiology, COVID-19, vaccination, hemodialysisOriginal ArticleMaintenance DialysisOriginal ArticleMaintenance Dialysisresearch-article20222022-06-01June 202210.2215/CJN.166212211555-90411555-905X2022-06-01T11:44:27-07:002022-06Clinical Journal of the American Society of NephrologyOriginal Article17666684376777976985076878177010.2215/CJN.14231021Thu, 28 Apr 2022 05:03:06 GMT-07:00Dapagliflozin and Kidney Outcomes in Hospitalized Patients with COVID-19 InfectionHeerspink, Hiddo J.L.Furtado, Remo H.M.Berwanger, OtavioKoch, Gary G.Martinez, FelipeMukhtar, OmarVerma, SubodhGasparyan, Samvel B.Tang, FengmingWindsor, Sheryl L.de Souza-Dantas, Vicente Césdel Sueldo, MildrenFrankel, RobertJavaheri, AliMaldonado, Rafael A.Morse, CarynMota-Gomes, MarcoShemin, DouglasSilva, Osvaldo LourençoTognon, Alexandre PereiraTwahirwa, MarcelBuenconsejo, JoanEsterline, RussellOscarsson, JanAmbery, PhilipLangkilde, Anna MariaKosiborod, Mikhail 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AngieHladunewich, MichelleYau, KevinGarg, Amit X.Leis, Jerome A.Levin, AdeeraKrajden, MelBlake, Peter G.2022-03-09T07:40:59-08:00doi:10.1681/ASN.2021091262hwp:resource-id:jnephrol;33/4/839American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologychronic dialysis, hospitalization, mortality, COVID-19, SARS-CoV-2, Ontario, maintenanceClinical ResearchClinical Researchresearch-article20222022-04-01April 202210.1681/ASN.20210912621046-66731533-34502022-03-09T07:40:59-08:002022-04Journal of the American Society of NephrologyClinical Research33483984910.1681/ASN.2021101395Tue, 08 Feb 2022 08:27:07 GMT-08:00Comparative Effectiveness of mRNA-based BNT162b2 Vaccine versus Adenovirus Vector–Based Ad26.COV2.S Vaccine for the Prevention of COVID-19 among Dialysis PatientsBrunelli, Steven M.Sibbel, ScottKarpinski, StephMarlowe, GilbertWalker, Adam G.Giullian, JeffreyVan Wyck, DavidKelley, TaraLazar, RachaelZywno, Meredith 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VinodThomson, PeterMethven, ShonaMark, Patrick B.2022-02-02T09:35:54-08:00doi:10.1681/ASN.2022010046hwp:resource-id:jnephrol;33/4/677American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical epidemiology, vaccination, COVID-19, dialysis, transplantation, kidney replacement therapyRapid CommunicationsRapid Communicationsresearch-article20222022-04-01April 202210.1681/ASN.20220100461046-66731533-34502022-02-02T09:35:54-08:002022-04Journal of the American Society of NephrologyRapid Communications3333467767712281428143068612281430143110.1681/ASN.2021121566Mon, 14 Feb 2022 10:29:21 GMT-08:00SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?Wijtvliet, VeerleWissing, Karl MartinAbramowicz, DanielLedeganck, Kristien J.2022-02-14T10:29:21-08:00doi:10.1681/ASN.2021121566hwp:resource-id:jnephrol;33/4/869American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyintradermal vaccination, kidney transplant recipients, SARS-CoV-2, third dose, T lymphocytes, COVID-19 vaccines, COVID-19Letter to the EditorLetter to the Editorletter20222022-04-01April 202210.1681/ASN.20211215661046-66731533-34502022-02-14T10:29:21-08:002022-04Journal of the American Society of NephrologyLetter to the Editor3344128698703027870871303310.34067/KID.0006632020Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: PROChung, Kevin K.Olson, Stephen W.2021-08-19T13:30:39-07:00doi:10.34067/KID.0006632020hwp:resource-id:kidney360;3/3/416American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, blood purification, COVID-19, cytokine storm, debates, extracorporeal, pathogen removal, sepsis, viremiaDebates in NephrologyDebates in Nephrologyresearch-article20222022-03-3110.34067/KID.00066320202641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Debates in Nephrology3341641810.34067/KID.0007382020Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: CONKashani, KianoushForni, Lui G.2021-08-19T13:30:39-07:00doi:10.34067/KID.0007382020hwp:resource-id:kidney360;3/3/419American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, cytokine storm, debates, extracorporeal purificationDebates in NephrologyDebates in Nephrologyresearch-article20222022-03-3110.34067/KID.00073820202641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Debates in Nephrology3341942210.34067/KID.0005242021Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: COMMENTARYOstermann, MarliesKoyner, Jay L.2021-08-19T13:30:39-07:00doi:10.34067/KID.0005242021hwp:resource-id:kidney360;3/3/423American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, blood purification, COVID-19, debatesModerator CommentaryModerator Commentaryarticle-commentary20222022-03-3110.34067/KID.00052420212641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Moderator Commentary3342342510.2215/CJN.11030821Thu, 24 Feb 2022 06:51:23 GMT-08:00Utilization of Palliative Care for Patients with COVID-19 and Acute Kidney Injury during a COVID-19 SurgeScherer, Jennifer S.Qian, YingzhiRau, Megan E.Soomro, Qandeel H.Sullivan, RyanLinton, JanelleZhong, JudyChodosh, JoshuaCharytan, David M.2022-02-24T06:51:23-08:00doi:10.2215/CJN.11030821hwp:resource-id:clinjasn;17/3/342American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyacute kidney injury, palliative care, COVID-19, hospice and palliative care nursing, SARS-CoV-2Original ArticleAcute Kidney Injury and ICU NephrologyOriginal ArticleAcute Kidney Injury and ICU Nephrologyresearch-article20222022-03-01March 202210.2215/CJN.110308211555-90411555-905X2022-02-24T06:51:23-08:002022-03Clinical Journal of the American Society of NephrologyOriginal Article173334233334933410.2215/CJN.12250921Thu, 10 Feb 2022 07:07:49 GMT-08:00Seroresponse to SARS-CoV-2 Vaccines among Maintenance Dialysis Patients over 6 MonthsHsu, Caroline M.Weiner, Daniel E.Manley, Harold J.Aweh, Gideon N.Ladik, VladimirFrament, JillMiskulin, DanaArgyropoulos, ChristosAbreo, KennethChin, AndrewGladish, ReginaldSalman, LoayJohnson, DougLacson, Eduardo K.2022-02-10T07:07:49-08:00doi:10.2215/CJN.12250921hwp:resource-id:clinjasn;17/3/403American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic hemodialysis, end-stage renal disease, peritoneal dialysis, COVID-19, COVID-19 vaccines, maintenance, SARS-CoV-2Original ArticleMaintenance DialysisOriginal ArticleMaintenance Dialysisresearch-article20222022-03-01March 202210.2215/CJN.122509211555-90411555-905X2022-02-10T07:07:49-08:002022-03Clinical Journal of the American Society of NephrologyOriginal Article173340333541333710.2215/CJN.10300721Thu, 10 Feb 2022 07:07:48 GMT-08:00Vaccination and COVID-19 Dynamics in Dialysis PatientsEl Karoui, KhalilHourmant, MaryvonneAyav, CaroleGlowacki, FrançoisCouchoud, CécileLapidus, Nathanaël,2022-02-10T07:07:48-08:00doi:10.2215/CJN.10300721hwp:resource-id:clinjasn;17/3/395American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, COVID-19, immunology, vaccination, SARS-CoV-2, hospitalization, hemodialysisOriginal ArticleMaintenance DialysisOriginal ArticleMaintenance Dialysisresearch-article20222022-03-01March 202210.2215/CJN.103007211555-90411555-905X2022-02-10T07:07:48-08:002022-03Clinical Journal of the American Society of NephrologyOriginal Article173339533540233710.2215/CJN.11190821Wed, 02 Feb 2022 06:42:04 GMT-08:00Renin-Angiotensin-Aldosterone System Inhibitors and the Risk of AKI in COVID-19 Compared with InfluenzaBirkelo, Bethany C.Parr, Sharidan K.Perkins, Amy M.Greevy, Robert A.Arroyo, Juan PabloHung, Adriana M.Vincz, Andrew J.Shah, Shailja C.Kapoor, TarunMatheny, Michael E.Siew, Edward D.2022-02-02T06:42:04-08:00doi:10.2215/CJN.11190821hwp:resource-id:clinjasn;17/3/423American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyACE inhibitors, acute kidney injury, COVID-19, renin-angiotensin systemResearch LetterResearch Letterletter20222022-03-01March 202210.2215/CJN.111908211555-90411555-905X2022-02-02T06:42:04-08:002022-03Clinical Journal of the American Society of NephrologyResearch Letter173423425Measures implemented to prevent transmission of severe acute respiratory syndrome coronavirus 2 in outpatient dialysis facilities may also help to prevent catheter-associated bloodstream infections in patients receiving hemodialysis. We used United States Renal Data System data to examine rates of antibiotic administration within dialysis facilities and rates of hospital admission for catheter-associated bloodstream infection from March 2018 through November 2020, and rates of hospitalization for sepsis, to address overall changes in hospitalization during the coronavirus disease 2019 (COVID-19) pandemic. Using logistic regression, we estimated year-over-year adjusted odds ratios of these events in 3-month intervals. During the first 6 months of the pandemic, rates of antibiotic administration were between 20% and 21% lower, and rates of hospitalization for catheter-associated bloodstream infection were between 17% and 24% lower than during corresponding periods in 2019, without significant changes in rates of hospitalization for sepsis. However, rates of catheter-associated events also decreased between 2018 and 2019, driven by reductions in facilities operated by a large dialysis provider. These data suggest that significant reductions in catheter-associated infections occurred during the pandemic, superimposed on nonpandemic-related reductions in some facilities before the pandemic. Even after the pandemic, it may be prudent to continue some COVID-19 mitigation measures to prevent catheter-associated bloodstream infections.10.2215/CJN.11360821Wed, 02 Feb 2022 06:42:04 GMT-08:00Catheter-Associated Bloodstream Infections among Patients on HemodialysisMeasures implemented to prevent transmission of severe acute respiratory syndrome coronavirus 2 in outpatient dialysis facilities may also help to prevent catheter-associated bloodstream infections in patients receiving hemodialysis. We used United States Renal Data System data to examine rates of antibiotic administration within dialysis facilities and rates of hospital admission for catheter-associated bloodstream infection from March 2018 through November 2020, and rates of hospitalization for sepsis, to address overall changes in hospitalization during the coronavirus disease 2019 (COVID-19) pandemic. Using logistic regression, we estimated year-over-year adjusted odds ratios of these events in 3-month intervals. During the first 6 months of the pandemic, rates of antibiotic administration were between 20% and 21% lower, and rates of hospitalization for catheter-associated bloodstream infection were between 17% and 24% lower than during corresponding periods in 2019, without significant changes in rates of hospitalization for sepsis. However, rates of catheter-associated events also decreased between 2018 and 2019, driven by reductions in facilities operated by a large dialysis provider. These data suggest that significant reductions in catheter-associated infections occurred during the pandemic, superimposed on nonpandemic-related reductions in some facilities before the pandemic. Even after the pandemic, it may be prudent to continue some COVID-19 mitigation measures to prevent catheter-associated bloodstream infections.Johansen, Kirsten L.Gilbertson, David T.Wetmore, James B.Peng, YiLiu, JiannongWeinhandl, Eric D.2022-02-02T06:42:04-08:00doi:10.2215/CJN.11360821hwp:resource-id:clinjasn;17/3/429American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States Renal Data System, hemodialysis, vascular access, COVID-19Insights from the USRDSInsights from the USRDSresearch-article20222022-03-01March 202210.2215/CJN.113608211555-90411555-905X2022-02-02T06:42:04-08:002022-03Clinical Journal of the American Society of NephrologyInsights from the USRDS173429433Farrukh.Koraishy@stonybrookmedicine.edu10.34067/KID.0005342021Mon, 29 Nov 2021 01:32:55 GMT-08:00Short- and Long-Term Recovery after Moderate/Severe AKI in Patients with and without COVID-19Sun, SiaoAnnadi, Raji R.Chaudhri, ImranMunir, KiranHajagos, JanosSaltz, JoelHoai, MinhMallipattu, Sandeep K.Moffitt, RichardKoraishy, Farrukh M.2021-11-29T13:32:55-08:00doi:10.34067/KID.0005342021hwp:resource-id:kidney360;3/2/242American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360AKI and ICU nephrology, AKI, CKD, COVID-19, Machine Learning, mortality, recoveryOriginal InvestigationAcute Kidney Injury and ICU NephrologyOriginal InvestigationAcute Kidney Injury and ICU Nephrologyresearch-article20222022-02-2410.34067/KID.00053420212641-76502021-11-29T13:32:55-08:002022-02-24Kidney360Original Investigation3224225710.34067/KID.0006472021Thu, 18 Nov 2021 09:22:57 GMT-08:00Collateral Effects and Mortality of Kidney Transplant Recipients during the COVID-19 PandemicSchmidt-Lauber, ChristianGünster, ChristianHuber, Tobias B.Spoden, MelissaGrahammer, Florian2021-11-18T09:22:57-08:00doi:10.34067/KID.0006472021hwp:resource-id:kidney360;3/2/325American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, acute allograft rejection, clinical epidemiology, COVID-19, epidemiology and outcomes, immunosuppression, kidney transplantation, mortality, transplant recipients, transplantationOriginal InvestigationTransplantationOriginal InvestigationTransplantationresearch-article20222022-02-2410.34067/KID.00064720212641-76502021-11-18T09:22:57-08:002022-02-24Kidney360Original Investigation3232533610.34067/KID.0006612021Fri, 03 Dec 2021 01:28:10 GMT-08:00COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International RegistryWaldman, MerylSoler, Maria JoseGarcía-Carro, ClaraLightstone, LizTurner-Stokes, TabithaGriffith, MeganTorras, JoanMartinez Valenzuela, LauraBestard, OriolGeddes, ColinFlossmann, OliverBudge, Kelly L.Cantarelli, ChiaraFiaccadori, EnricoDelsante, MarcoMorales, EnriqueGutierrez, EduardoNiño-Cruz, Jose A.Martinez-Rueda, Armando J.Comai, GiorgiaBini, ClaudiaLa Manna, GaetanoSlon, Maria F.Manrique, JoaquinAvello, AlejandroFernandez-Prado, RaulOrtiz, AlbertoMarinaki, SmaragdiMartin Varas, Carmen RitaRabasco Ruiz, CristinaSierra-Carpio, MilagrosGarcía-Agudo, RebecaFernández Juárez, GemaHamilton, Alexander J.Bruchfeld, AnnetteChrysochou, ConstantinaHoward, LilianSinha, SmeetaLeach, TimAgraz Pamplona, IreneMaggiore, UmbertoCravedi, Paolo2021-12-03T13:28:10-08:00doi:10.34067/KID.0006612021hwp:resource-id:kidney360;3/2/293American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360glomerular and tubulointerstitial diseases, COVID-19, follow-up studies, glomerular disease, kidney glomerulus, registriesOriginal InvestigationGlomerular and Tubulointerstitial DiseasesOriginal InvestigationGlomerular and Tubulointerstitial Diseasesresearch-article20222022-02-2410.34067/KID.00066120212641-76502021-12-03T13:28:10-08:002022-02-24Kidney360Original Investigation3229330610.34067/KID.0006152021Fri, 03 Dec 2021 01:28:10 GMT-08:00A Propensity Score–Matched Observational Study of Remdesivir in Patients with COVID-19 and Severe Kidney DiseaseSeethapathy, RituvanthikaaZhao, SophiaLong, Joshua D.Strohbehn, Ian A.Sise, Meghan E.2021-12-03T13:28:10-08:00doi:10.34067/KID.0006152021hwp:resource-id:kidney360;3/2/269American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360chronic kidney disease, acute kidney injury, antiviral, COVID-19, dialysis, propensity score, remdesivir, SARS-CoV-2Original InvestigationChronic Kidney DiseaseOriginal InvestigationChronic Kidney Diseaseresearch-article20222022-02-2410.34067/KID.00061520212641-76502021-12-03T13:28:10-08:002022-02-24Kidney360Original Investigation3226927810.1681/ASN.2021101296Mon, 31 Jan 2022 10:00:27 GMT-08:00Confirmed Drop in Treatment of Patients with Incident End-Stage Kidney Disease During the Novel Coronavirus Disease 2019 PandemicJacobs, LucasDevresse, ArnaudBaudoux, ThomasCollart, Frédéric2022-01-31T10:00:27-08:00doi:10.1681/ASN.2021101296hwp:resource-id:jnephrol;33/2/455American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyend stage kidney disease, epidemiology and outcomes, hemodialysis, peritoneal dialysis, transplantation, COVID-19, SARS-CoV-2Letter to the EditorLetter to the Editorletter20222022-02-01February 202210.1681/ASN.20211012961046-66731533-34502022-01-31T10:00:27-08:002022-02Journal of the American Society of NephrologyLetter to the Editor33221145545529484554572957Kidney disease is a known risk factor for poor outcomes of COVID-19 and many other serious infections. Conversely, infection is the second most common cause of death in patients with kidney disease. However, little is known about the underlying secondary immunodeficiency related to kidney disease (SIDKD). In contrast to cardiovascular disease related to kidney disease, which has triggered countless epidemiologic, clinical, and experimental research activities or interventional trials, investments in tracing, understanding, and therapeutically targeting SIDKD have been sparse. As a call for more awareness of SIDKD as an imminent unmet medical need that requires rigorous research activities at all levels, we review the epidemiology of SIDKD and the numerous aspects of the abnormal immunophenotype of patients with kidney disease. We propose a definition of SIDKD and discuss the pathogenic mechanisms of SIDKD known thus far, including more recent insights into the unexpected immunoregulatory roles of elevated levels of FGF23 and hyperuricemia and shifts in the secretome of the intestinal microbiota in kidney disease. As an ultimate goal, we should aim to develop therapeutics that can reduce mortality due to infections in patients with kidney disease by normalizing host defense to pathogens and immune responses to vaccines.10.1681/ASN.2021091257Tue, 14 Dec 2021 07:50:01 GMT-08:00Secondary Immunodeficiency Related to Kidney Disease (SIDKD)—Definition, Unmet Need, and MechanismsKidney disease is a known risk factor for poor outcomes of COVID-19 and many other serious infections. Conversely, infection is the second most common cause of death in patients with kidney disease. However, little is known about the underlying secondary immunodeficiency related to kidney disease (SIDKD). In contrast to cardiovascular disease related to kidney disease, which has triggered countless epidemiologic, clinical, and experimental research activities or interventional trials, investments in tracing, understanding, and therapeutically targeting SIDKD have been sparse. As a call for more awareness of SIDKD as an imminent unmet medical need that requires rigorous research activities at all levels, we review the epidemiology of SIDKD and the numerous aspects of the abnormal immunophenotype of patients with kidney disease. We propose a definition of SIDKD and discuss the pathogenic mechanisms of SIDKD known thus far, including more recent insights into the unexpected immunoregulatory roles of elevated levels of FGF23 and hyperuricemia and shifts in the secretome of the intestinal microbiota in kidney disease. As an ultimate goal, we should aim to develop therapeutics that can reduce mortality due to infections in patients with kidney disease by normalizing host defense to pathogens and immune responses to vaccines.Steiger, StefanieRossaint, JanZarbock, AlexanderAnders, Hans-Joachim2021-12-14T07:50:01-08:00doi:10.1681/ASN.2021091257hwp:resource-id:jnephrol;33/2/259American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologykidney disease, immunodeficiency, infection, chronic inflammationReviewReviewreview-article20222022-02-01February 202210.1681/ASN.20210912571046-66731533-34502021-12-14T07:50:01-08:002022-02Journal of the American Society of NephrologyReview33225927810.34067/KID.0004562021Thu, 27 Jan 2022 08:00:35 GMT-08:00The Downside of Telephone Health Visits in a Kidney Transplant Patient during the COVID-19 PandemicRoss-Smith, Maree S.Wallace, Hannah E.2022-01-27T08:00:35-08:00doi:10.34067/KID.0004562021hwp:resource-id:kidney360;3/1/190American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, dialysis, fistula, telehealth, transplantationClinical Images in Nephrology and DialysisClinical Images in Nephrology and Dialysisresearch-article20222022-01-2710.34067/KID.00045620212641-76502022-01-27T08:00:35-08:002022-01-27Kidney360Clinical Images in Nephrology and Dialysis3119019110.34067/KID.0005522021Fri, 05 Nov 2021 09:54:32 GMT-07:00Single-Cell RNA Sequencing of Urinary Cells Reveals Distinct Cellular Diversity in COVID-19–Associated AKICheung, Matthew D.Erman, Elise N.Liu, ShanrunErdmann, Nathaniel B.Ghajar-Rahimi, GelareMoore, Kyle H.Edberg, Jeffrey C.George, James F.Agarwal, Anupam2021-11-05T09:54:32-07:00doi:10.34067/KID.0005522021hwp:resource-id:kidney360;3/1/28American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, acute kidney injury, basic science, COVID-19, SARS-CoV-2, single-cell RNA sequencing, urineOriginal InvestigationAcute Kidney Injury and ICU NephrologyOriginal InvestigationAcute Kidney Injury and ICU Nephrologyresearch-article20222022-01-2710.34067/KID.00055220212641-76502021-11-05T09:54:32-07:002022-01-27Kidney360Original Investigation31283610.34067/KID.0007722021Thu, 27 Jan 2022 08:00:34 GMT-08:00Durable Protection after Anti–SARS-CoV-2 Monoclonal Antibody TherapyMisch, Elizabeth A.2022-01-27T08:00:34-08:00doi:10.34067/KID.0007722021hwp:resource-id:kidney360;3/1/8American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, COVID-19, kidney transplantation, monoclonal antibody therapy, SARS-CoV-2EditorialEditorialeditorial20222022-01-2710.34067/KID.00077220212641-76502022-01-27T08:00:34-08:002022-01-27Kidney360Editorial3181010.34067/KID.0005732021Wed, 20 Oct 2021 01:24:47 GMT-07:00SARS-CoV-2 Neutralizing Monoclonal Antibodies for the Treatment of COVID-19 in Kidney Transplant RecipientsWang, Aileen X.Busque, StephanKuo, JamieSingh, UpinderRöeltgen, KatharinaPinsky, Benjamin A.Chertow, Glenn M.Scandling, John D.Lenihan, Colin R.2021-10-20T13:24:47-07:00doi:10.34067/KID.0005732021hwp:resource-id:kidney360;3/1/133American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, COVID-19, immunosuppression, kidney transplant, monoclonal antibodies, SARS-CoV-2Original InvestigationTransplantationOriginal InvestigationTransplantationresearch-article20222022-01-2710.34067/KID.00057320212641-76502021-10-20T13:24:47-07:002022-01-27Kidney360Original Investigation3113314310.2215/CJN.11820921Wed, 22 Dec 2021 11:26:04 GMT-08:00Neutralization of SARS-CoV-2 Variants of Concern in Kidney Transplant Recipients after Standard COVID-19 VaccinationBenning, LouiseMorath, ChristianBartenschlager, MarieNusshag, ChristianKälble, FlorianBuylaert, MirabelSchaier, MatthiasBeimler, JörgKlein, KatrinGrenz, JuliaReichel, PaulaHidmark, AsaPonath, GeraldTöllner, MaximilianReineke, MarvinRieger, SusanneTönshoff, BurkhardSchnitzler, PaulZeier, MartinSüsal, CanerBartenschlager, RalfSpeer, Claudius2021-12-22T11:26:04-08:00doi:10.2215/CJN.11820921hwp:resource-id:clinjasn;17/1/98American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, SARS-CoV-2, kidney transplantation, variants of concern, vaccinationOriginal ArticleTransplantationOriginal ArticleTransplantationresearch-article20222022-01-01January 202210.2215/CJN.118209211555-90411555-905X2021-12-22T11:26:04-08:002022-01Clinical Journal of the American Society of NephrologyOriginal Article1711198131062510.2215/CJN.14881121Wed, 22 Dec 2021 11:26:04 GMT-08:00Protection against SARS-CoV-2 Variants with COVID-19 Vaccination in Kidney Transplant RecipientsBertrand, DominiqueCandon, Sophie2021-12-22T11:26:04-08:00doi:10.2215/CJN.14881121hwp:resource-id:clinjasn;17/1/3American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologySARS-CoV-2, COVID-19, vaccination, kidney transplantationEditorialEditorialeditorial20222022-01-01January 202210.2215/CJN.148811211555-90411555-905X2021-12-22T11:26:04-08:002022-01Clinical Journal of the American Society of NephrologyEditorial1711139815106210.2215/CJN.15071121Wed, 22 Dec 2021 11:26:05 GMT-08:00An Honorable and Ongoing FightConway, Paul T.2021-12-22T11:26:05-08:00doi:10.2215/CJN.15071121hwp:resource-id:clinjasn;17/1/1American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney transplantation, nephrology, COVID-19, immunosuppressed, vaccines, vaccination, monoclonal antibodies, Delta variant, Kidney Health InitiativePatient VoicePatient Voiceeditorial20222022-01-01January 202210.2215/CJN.150711211555-90411555-905X2021-12-22T11:26:05-08:002022-01Clinical Journal of the American Society of NephrologyPatient Voice1711119832106510.1681/ASN.2021060778Wed, 17 Nov 2021 10:26:37 GMT-08:00Real-World Effectiveness and Immunogenicity of BNT162b2 and mRNA-1273 SARS-CoV-2 Vaccines in Patients on HemodialysisSibbel, ScottMcKeon, KatherineLuo, JiacongWendt, KarlWalker, Adam G.Kelley, TaraLazar, RachaelZywno, Meredith L.Connaire, Jeffrey J.Tentori, FrancescaYoung, AmyBrunelli, Steven M.2021-11-17T10:26:37-08:00doi:10.1681/ASN.2021060778hwp:resource-id:jnephrol;33/1/49American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyend stage kidney disease, end-stage renal disease, ESRD, dialysis, coronavirus disease 2019, COVID-19, SARS-CoV-2, vaccine, BNT162 vaccine, RNA, messengerRapid CommunicationsRapid Communicationsresearch-article20222022-01-01January 202210.1681/ASN.20210607781046-66731533-34502021-11-17T10:26:37-08:002022-01Journal of the American Society of NephrologyRapid Communications331495710.1681/ASN.2021070936Wed, 13 Oct 2021 08:38:50 GMT-07:00COVID-19 Vaccine Type and Humoral Immune Response in Patients Receiving DialysisGarcia, PabloAnand, ShuchiHan, JialinMontez-Rath, Maria E.Sun, SumiShang, TiffanyParsonnet, JulieChertow, Glenn M.Schiller, BrigitteAbra, Graham2021-10-13T08:38:50-07:00doi:10.1681/ASN.2021070936hwp:resource-id:jnephrol;33/1/33American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologydialysis, vaccine, SARS-CoV-2, ESKD, immunity, humoral, immunization, COVID-19Research LetterResearch Letterletter20222022-01-01January 202210.1681/ASN.20210709361046-66731533-34502021-10-13T08:38:50-07:002022-01Journal of the American Society of NephrologyResearch Letter331333710.34067/KID.0005292021Sat, 23 Oct 2021 06:07:33 GMT-07:00Scarce Health Care Resources and Equity during COVID-19: Lessons from the History of Kidney Failure TreatmentButler, Catherine R.Wightman, Aaron G.2021-10-23T06:07:33-07:00doi:10.34067/KID.0005292021hwp:resource-id:kidney360;2/12/2024American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, coronavirus disease 2019, COVID-19, delivery of health care, dialysis, ethics, health care resources, policy, renal insufficiency, triagePerspectivePerspectiveresearch-article20212021-12-3010.34067/KID.00052920212641-76502021-10-23T06:07:33-07:002021-12-30Kidney360Perspective2122024202610.34067/KID.0004372021Wed, 22 Sep 2021 05:30:15 GMT-07:00Clinical Course of SARS-CoV-2 Infection in Adults with ESKD Receiving Outpatient HemodialysisBardossy, Ana CeciliaKorhonen, LaurenSchatzman, SabrinaGable, PaigeHerzig, CarolynBrown, Nicole E.Beshearse, ElizabethVarela, KateSabour, SarahLyons, Amanda K.Overton, RahsaanHudson, MatthewHernandez-Romieu, Alfonso C.Alvarez, JorgeRoman, KaylinWeng, MarkSoda, ElizabethPatel, Priti R.Grate, CrystalDalrymple, Lorien S.Wingard, Rebecca L.Thornburg, Natalie J.Halpin, Alison S. LauferFolster, Jennifer M.Tobin-D’Angelo, MelissaLea, JaniceApata, IbironkeMcDonald, L. CliffordBrown, Allison C.Kutty, Preeta K.Novosad, ShannonWilson, W. WyattTobolowsky, FarrellGilbert, Sarah E.Huang, JenniferGualandi, NicoleAnsari, UzmaPerry-Dow, K. AllisonMcAllister, Gillian A.Whitworth, CarrieSanders, CarrieTamin, AzaibiHarcourt, Jennifer L.Freeman, BrandiLester, SandraMills, LisaStumpf, MeganFurin, WilliamSpicer, LoriAdamczyk, MichelleChan, MonicaBhatnagar, AmeliaReese, NatashiaBalbuena, RocioAnderson, KarenLonsway, DavidBreaker, ErinRasheed, James K.Houston, HollisCrayton, KarlosTran, LisaCampbell, DavinaPaulick, Ashley LynGade, LalithaGalloway, ReneeHartloge, ClaireJenkins, BrentMedrzycki, MagdalenaSahibzada, KashifShewmaker, PatriciaWynn, NhienVelusamy, SrinivasanWong, PhiliZheng, HaoQiangTejada-Strop, AlexandraJain, Shilpi2021-09-22T05:30:15-07:00doi:10.34067/KID.0004372021hwp:resource-id:kidney360;2/12/1917American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, chronic kidney failure, COVID-19, dialysis, end-stage renal disease, ESRD, infectiousness, infectivity, outpatients, SARS-CoV-2Original InvestigationDialysisOriginal InvestigationDialysisresearch-article20212021-12-3010.34067/KID.00043720212641-76502021-09-22T05:30:15-07:002021-12-30Kidney360Original Investigation2121917192710.2215/CJN.09110721Wed, 03 Nov 2021 09:34:38 GMT-07:00Humoral Response to BNT162b2 mRNA SARS-CoV-2 Vaccine in Patients with Nondialysis Chronic Kidney DiseaseKervella, DelphineBraud, PierreGarandeau, ClairePhelizot, CelineAmbrosi, XavierBlancho, GillesHourmant, MaryvonneFigueres, LucileBlancho, GillesBranchereau, JulienCantarovich, DiegoChapelet, AgnèsDantal, JacquesDeltombe, ClémentFigueres, LucileGaisne, RaphaelGarandeau, ClaireGiral, MagaliGourraud-Vercel, CarolineHourmant, MaryvonneKaram, GeorgesKerleau, ClarisseKervella, DelphineMasset, ChristopheMeurette, AurélieVille, SimonKandell, ChristineMoreau, AnneRenaudin, KarineDelbos, FlorentWalencik, AlexandreDevis, Anne2021-11-03T09:34:38-07:00doi:10.2215/CJN.09110721hwp:resource-id:clinjasn;16/12/1872American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, SARS-CoV-2, chronic kidney disease, vaccineResearch LettersResearch Lettersletter20212021-12-01December 202110.2215/CJN.091107211555-90411555-905X2021-11-03T09:34:38-07:002021-12Clinical Journal of the American Society of NephrologyResearch Letters16121872187410.2215/CJN.10170721Mon, 20 Sep 2021 10:40:31 GMT-07:00Humoral Response to One and Two Doses of ChAdOx1-S Vaccine in Patients on HemodialysisYadav, Ashok KumarGondil, Vijay SinghSingla, ManishGoyal, AjayKaushal, RakaChauhan, MunishJha, Vivekanand2021-09-20T10:40:31-07:00doi:10.2215/CJN.10170721hwp:resource-id:clinjasn;16/12/1875American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyhemodialysis, COVID-19, AntibodyResearch LettersResearch Lettersletter20212021-12-01December 202110.2215/CJN.101707211555-90411555-905X2021-09-20T10:40:31-07:002021-12Clinical Journal of the American Society of NephrologyResearch Letters16121875187610.2215/CJN.01070121Tue, 07 Dec 2021 11:35:23 GMT-08:00APOL1 Risk Variants and Acute Kidney Injury in Black Americans with COVID-19Larsen, Christopher P.Wickman, Terrance J.Braga, Juarez R.Matute-Trochez, Luis A.Hasty, Anna E.Buckner, Lyndsey R.Arthur, John M.Haun, Randy S.Velez, Juan Carlos Q.2021-12-07T11:35:23-08:00doi:10.2215/CJN.01070121hwp:resource-id:clinjasn;16/12/1790American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyacute renal failure, genetic renal disease, COVID-19, apolipoprotein L1, acute kidney injuryOriginal ArticlesAcute Kidney Injury and ICU NephrologyOriginal ArticlesAcute Kidney Injury and ICU Nephrologyresearch-article20212021-12-01December 202110.2215/CJN.010701211555-90411555-905X2021-12-07T11:35:23-08:002021-12Clinical Journal of the American Society of NephrologyOriginal Articles161212179017791796178010.1681/ASN.2021070966Tue, 19 Oct 2021 05:27:18 GMT-07:00B and T Cell Responses after a Third Dose of SARS-CoV-2 Vaccine in Kidney Transplant RecipientsSchrezenmeier, EvaRincon-Arevalo, HectorStefanski, Ana-LuisaPotekhin, AlexanderStaub-Hohenbleicher, HenrietteChoi, MiraBachmann, FriederikeProβ, VanessaHammett, CharlotteSchrezenmeier, HubertLudwig, CarolinJahrsdörfer, BerndLino, Andreia C.Eckardt, Kai-UweKotsch, KatjaDörner, ThomasBudde, KlemensSattler, ArneHalleck, Fabian2021-10-19T05:27:18-07:00doi:10.1681/ASN.2021070966hwp:resource-id:jnephrol;32/12/3027American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, vaccine, B cells, T cells, T-lymphocytes, SARS-CoV-2, kidney transplantationRapid CommunicationsRapid Communicationsresearch-article20212021-12-01December 202110.1681/ASN.20210709661046-66731533-34502021-10-19T05:27:18-07:002021-12Journal of the American Society of NephrologyRapid Communications32121244302729778698703033297886987110.1681/ASN.2021070908Wed, 29 Sep 2021 09:52:14 GMT-07:00Predictors and Dynamics of the Humoral and Cellular Immune Response to SARS-CoV-2 mRNA Vaccines in Hemodialysis Patients: A Multicenter Observational StudyVan Praet, JensReynders, MarijkeDe Bacquer, DirkViaene, LiesbethSchoutteten, Melanie K.Caluwé, RogierDoubel, PeterHeylen, LineDe Bel, Annelies V.Van Vlem, BrunoSteensels, DeborahDe Vriese, An S.2021-09-29T09:52:14-07:00doi:10.1681/ASN.2021070908hwp:resource-id:jnephrol;32/12/3208American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical trial, dialysis, SARS-CoV-2, vaccination, COVID-19, cellular immunityClinical ResearchClinical Researchresearch-article20212021-12-01December 202110.1681/ASN.20210709081046-66731533-34502021-09-29T09:52:14-07:002021-12Journal of the American Society of NephrologyClinical Research32123208322010.1681/ASN.2021040573Fri, 01 Oct 2021 02:00:11 GMT-07:00Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 InfectionCravedi, PaoloAhearn, PatrickWang, LinYalamarti, TanujaHartzell, SusanAzzi, YorgMenon, Madhav C.Jain, AdityaBillah, MarzuqFernandez-Vina, MarceloGebel, Howard M.Woodle, E. SteveHaddad, Natalie S.Morrison-Porter, AndreaLee, F. Eun-HyungSanz, IgnacioAkalin, EnverGirnita, AlinMaltzman, Jonathan S.2021-10-01T14:00:11-07:00doi:10.1681/ASN.2021040573hwp:resource-id:jnephrol;32/12/3221American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyend stage kidney disease, immunology, kidney transplantation, antibodies, SARS-Co-V-2, COVID-19Clinical ResearchClinical Researchresearch-article20212021-12-01December 202110.1681/ASN.20210405731046-66731533-34502021-10-01T14:00:11-07:002021-12Journal of the American Society of NephrologyClinical Research32123221323010.34067/KID.0005372021Thu, 16 Sep 2021 09:50:05 GMT-07:00Glomerular Disease in Temporal Association with SARS-CoV-2 Vaccination: A Series of 29 CasesCaza, Tiffany N.Cassol, Clarissa A.Messias, NidiaHannoudi, AndrewHaun, Randy S.Walker, Patrick D.May, Rebecca M.Seipp, Regan M.Betchick, Elizabeth J.Amin, HassanZiadie, Mandolin S.Haderlie, MichaelEduwu-okwuwa, JoyVancea, IrinaSeek, MelvinElashi, Essam B.Shenoy, GaneshKhalillullah, SayeedFlaxenburg, Jesse A.Brandt, JohnDiamond, Matthew J.Frome, AdamKim, Eugene H.Schlessinger, GregoryUlozas, ErlandasWeatherspoon, Janice L.Hoerschgen, Ethan ThomasFabian, Steven L.Bae, Sung YongIqbal, BilalChouhan, Kanwalijit K.Karam, ZeinaHenry, James T.Larsen, Christopher P.2021-09-16T09:50:05-07:00doi:10.34067/KID.0005372021hwp:resource-id:kidney360;2/11/1770American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360glomerular and tubulointerstitial diseases, ANCA, APOL1, collapsing glomerulopathy, COVID-19, crescentic glomerulonephritis, IgA nephropathy, lupus nephritis, membranous nephropathy, minimal change disease, SARS-CoV-2 vaccineOriginal InvestigationGlomerular and Tubulointerstitial DiseasesOriginal InvestigationGlomerular and Tubulointerstitial Diseasesresearch-article20212021-11-2510.34067/KID.00053720212641-76502021-09-16T09:50:05-07:002021-11-25Kidney360Original Investigation2111770178010.2215/CJN.02690221Wed, 29 Sep 2021 01:48:33 GMT-07:00COVID-19–Associated Mortality among Kidney Transplant Recipients and Candidates in the United StatesMohan, SumitKing, Kristen L.Husain, S. AliSchold, Jesse D.2021-09-29T13:48:33-07:00doi:10.2215/CJN.02690221hwp:resource-id:clinjasn;16/11/1695American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney transplantation, mortality, COVID-19, United StatesOriginal ArticlesTransplantationOriginal ArticlesTransplantationresearch-article20212021-11-01November 202110.2215/CJN.026902211555-90411555-905X2021-09-29T13:48:33-07:002021-11Clinical Journal of the American Society of NephrologyOriginal Articles16111695170310.2215/CJN.06450521Mon, 26 Jul 2021 10:16:49 GMT-07:00Humoral Response to mRNA versus an Adenovirus Vector-Based SARS-CoV-2 Vaccine in Dialysis PatientsMulhern, Jeffrey G.Fadia, AmitPatel, RuchirFicociello, Linda H.Willetts, JoannaDahne-Steuber, Ines A.Pollan, Melanie C.Mullon, ClaudyDeLisi, JosephineJohnson, CurtisMysayphonh, ChanceKossmann, Robert J.Anger, Michael S.Hymes, Jeffrey L.2021-07-26T10:16:49-07:00doi:10.2215/CJN.06450521hwp:resource-id:clinjasn;16/11/1720American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, COVID-19, vaccination, antibody, SARS-CoV-2Research LetterResearch Letterletter20212021-11-01November 202110.2215/CJN.064505211555-90411555-905X2021-07-26T10:16:49-07:002021-11Clinical Journal of the American Society of NephrologyResearch Letter161117201722Despite evidence of multiorgan tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with coronavirus disease 2019 (COVID-19), direct viral kidney invasion has been difficult to demonstrate. The question of whether SARS-CoV2 can directly infect the kidney is relevant to the understanding of pathogenesis of AKI and collapsing glomerulopathy in patients with COVID-19. Methodologies to document SARS-CoV-2 infection that have been used include immunohistochemistry, immunofluorescence, RT-PCR, in situ hybridization, and electron microscopy. In our review of studies to date, we found that SARS-CoV-2 in the kidneys of patients with COVID-19 was detected in 18 of 94 (19%) by immunohistochemistry, 71 of 144 (49%) by RT-PCR, and 11 of 84 (13%) by in situ hybridization. In a smaller number of patients with COVID-19 examined by immunofluorescence, SARS-CoV-2 was detected in 10 of 13 (77%). In total, in kidneys from 102 of 235 patients (43%), the presence of SARS-CoV-2 was suggested by at least one of the methods used. Despite these positive findings, caution is needed because many other studies have been negative for SARS-CoV-2 and it should be noted that when detected, it was only in kidneys obtained at autopsy. There is a clear need for studies from kidney biopsies, including those performed at early stages of the COVID-19–associated kidney disease. Development of tests to detect kidney viral infection in urine samples would be more practical as a noninvasive way to evaluate SARS-CoV-2 infection during the evolution of COVID-19–associated kidney disease.10.2215/CJN.04560421Mon, 14 Jun 2021 12:53:52 GMT-07:00Evidence For and Against Direct Kidney Infection by SARS-CoV-2 in Patients with COVID-19Despite evidence of multiorgan tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with coronavirus disease 2019 (COVID-19), direct viral kidney invasion has been difficult to demonstrate. The question of whether SARS-CoV2 can directly infect the kidney is relevant to the understanding of pathogenesis of AKI and collapsing glomerulopathy in patients with COVID-19. Methodologies to document SARS-CoV-2 infection that have been used include immunohistochemistry, immunofluorescence, RT-PCR, in situ hybridization, and electron microscopy. In our review of studies to date, we found that SARS-CoV-2 in the kidneys of patients with COVID-19 was detected in 18 of 94 (19%) by immunohistochemistry, 71 of 144 (49%) by RT-PCR, and 11 of 84 (13%) by in situ hybridization. In a smaller number of patients with COVID-19 examined by immunofluorescence, SARS-CoV-2 was detected in 10 of 13 (77%). In total, in kidneys from 102 of 235 patients (43%), the presence of SARS-CoV-2 was suggested by at least one of the methods used. Despite these positive findings, caution is needed because many other studies have been negative for SARS-CoV-2 and it should be noted that when detected, it was only in kidneys obtained at autopsy. There is a clear need for studies from kidney biopsies, including those performed at early stages of the COVID-19–associated kidney disease. Development of tests to detect kidney viral infection in urine samples would be more practical as a noninvasive way to evaluate SARS-CoV-2 infection during the evolution of COVID-19–associated kidney disease.Hassler, LuiseReyes, FabiolaSparks, Matthew A.Welling, PaulBatlle, Daniel2021-06-14T12:53:52-07:00doi:10.2215/CJN.04560421hwp:resource-id:clinjasn;16/11/1755American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, proximal tubule, podocyte, interstitial nephritis, pyelonephritisFeatureFeatureresearch-article20212021-11-01November 202110.2215/CJN.045604211555-90411555-905X2021-06-14T12:53:52-07:002021-11Clinical Journal of the American Society of NephrologyFeature16111755176510.1681/ASN.2021040432Wed, 04 Aug 2021 12:11:00 GMT-07:00Immunogenicity of SARS-CoV-2 Vaccine in DialysisLacson, EduardoArgyropoulos, Christos P.Manley, Harold J.Aweh, GideonChin, Andrew I.Salman, Loay H.Hsu, Caroline M.Johnson, Doug S.Weiner, Daniel E.2021-08-04T12:11:00-07:00doi:10.1681/ASN.2021040432hwp:resource-id:jnephrol;32/11/2735American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologydialysis, end-stage kidney disease, chronic kidney disease, vaccine, SARS-CoV-2, COVID-19, immune deficiency, clinical immunology, end-stage kidney diseaseRapid CommunicationsRapid Communicationsresearch-article20212021-11-01November 202110.1681/ASN.20210404321046-66731533-34502021-08-04T12:11:00-07:002021-11Journal of the American Society of NephrologyRapid Communications32112735274210.1681/ASN.2021060734Wed, 01 Sep 2021 06:00:08 GMT-07:00Kidney Outcomes in Long COVIDBowe, BenjaminXie, YanXu, EvanAl-Aly, Ziyad2021-09-01T06:00:08-07:00doi:10.1681/ASN.2021060734hwp:resource-id:jnephrol;32/11/2851American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyESRD, ESKD, acute kidney injury, post-acute sequelae of SARS-CoV-2 infection, PASC, post-acute COVID, long COVID, eGFR decline, kidney function, COVID-19Clinical EpidemiologyClinical Epidemiologyresearch-article20212021-11-01November 202110.1681/ASN.20210607341046-66731533-34502021-09-01T06:00:08-07:002021-11Journal of the American Society of NephrologyClinical Epidemiology32112851286210.1681/ASN.2021040579Fri, 17 Sep 2021 10:39:33 GMT-07:00Changes in Treatment of Patients with Incident ESKD during the Novel Coronavirus Disease 2019 PandemicWetmore, James B.Johansen, Kirsten L.Liu, JiannongPeng, YiGilbertson, David T.Weinhandl, Eric D.2021-09-17T10:39:33-07:00doi:10.1681/ASN.2021040579hwp:resource-id:jnephrol;32/11/2948American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, dialysis, ESKD, transplantation, USRDSClinical ResearchClinical Researchresearch-article20212021-11-01November 202110.1681/ASN.20210405791046-66731533-34502021-09-17T10:39:33-07:002021-11Journal of the American Society of NephrologyClinical Research3211222948455455295745545710.1681/ASN.2021070931Wed, 20 Oct 2021 07:19:19 GMT-07:00Longitudinal Outcomes of COVID-19–Associated Collapsing Glomerulopathy and Other PodocytopathiesKudose, SatoruSantoriello, DominickBomback, Andrew S.Sekulic, MiroslavBatal, IbrahimStokes, M. BarryGhavami, Iman A.Kim, Jung S.Marasa, MaddalenaXu, KatherinePeleg, YonatanBarasch, JonathanCanetta, PietroRasouly, Hila MiloGharavi, Ali G.Markowitz, Glen S.D’Agati, Vivette D.2021-10-20T07:19:19-07:00doi:10.1681/ASN.2021070931hwp:resource-id:jnephrol;32/11/2958American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologycollapsing FSGS, virology, pathology, COVID-19, kidney biopsy, podocytopathy, SARS, FSGSClinical ResearchClinical Researchresearch-article20212021-11-01November 202110.1681/ASN.20210709311046-66731533-34502021-10-20T07:19:19-07:002021-11Journal of the American Society of NephrologyClinical Research32112958296910.1681/ASN.2021060812Mon, 19 Jul 2021 11:44:34 GMT-07:00Testing of Worn Face Masks for Timely Diagnosis of SARS-CoV-2 in Hemodialysis PatientsWang, XiaolingGrobe, NadjaHaq, ZahinThwin, OhnmarFuentes, Lemuel RiveraMaddux, DuganKotanko, Peter2021-07-19T11:44:34-07:00doi:10.1681/ASN.2021060812hwp:resource-id:jnephrol;32/11/2728American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologymask, dialysis, SARS-CoV-2, COVID-19Research LettersResearch Lettersletter20212021-11-01November 202110.1681/ASN.20210608121046-66731533-34502021-07-19T11:44:34-07:002021-11Journal of the American Society of NephrologyResearch Letters32112728273010.1681/ASN.2021050672Fri, 29 Oct 2021 12:45:34 GMT-07:00Impaired Humoral but Substantial Cellular Immune Response to Variants of Concern B1.1.7 and B.1.351 in Hemodialysis Patients after Vaccination with BNT162b2Thieme, Constantin J.Blazquez-Navarro, ArturoSafi, LemaKaliszczyk, SviatlanaPaniskaki, KrystalleniaNeumann, Isabel E.Schmidt, KitaStockhausen, MaraHörstrup, JanCinkilic, OcanFlitsch-Kiefner, LinusMeister, Toni L.Marheinecke, CorinnaPfaender, StephanieSteinmann, EikeSeibert, Felix S.Stervbo, UlrikWesthoff, Timm H.Roch, ToralfBabel, Nina2021-10-29T12:45:34-07:00doi:10.1681/ASN.2021050672hwp:resource-id:jnephrol;32/11/2725American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologychronic hemodialysis, clinical immunology, kidney disease, SARS-CoV-2, vaccination, infectious diseases, mRNA vaccine, immunity, cellular, COVID-19Research LettersResearch Lettersletter20212021-11-01November 202110.1681/ASN.20210506721046-66731533-34502021-10-29T12:45:34-07:002021-11Journal of the American Society of NephrologyResearch Letters32112725272710.1681/ASN.2021010059Fri, 04 Jun 2021 11:03:04 GMT-07:00High SARS-CoV-2 Viral Load in Urine Sediment Correlates with Acute Kidney Injury and Poor COVID-19 OutcomeCaceres, Paulo S.Savickas, GinaMurray, Shannon L.Umanath, KausikUduman, JuniorYee, JerryLiao, Tang-DongBolin, StevenLevin, Albert M.Khan, Moomal N.Sarkar, SarahFitzgerald, JamieMaskey, DipakOrmsby, Adrian H.Sharma, YuvrajOrtiz, Pablo A.2021-06-04T11:03:04-07:00doi:10.1681/ASN.2021010059hwp:resource-id:jnephrol;32/10/2517American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyacute renal failure, virology, renal injury, mortality risk, COVID-19Basic ResearchBasic Researchresearch-article20212021-10-01October 202110.1681/ASN.20210100591046-66731533-34502021-06-04T11:03:04-07:002021-10Journal of the American Society of NephrologyBasic Research3210102517i2528i10.1681/ASN.2021050611Fri, 11 Jun 2021 06:31:07 GMT-07:00Antibody Response to COVID-19 Vaccination in Patients Receiving DialysisAnand, ShuchiMontez-Rath, Maria E.Han, JialinGarcia, PabloCadden, LinaCelHunsader, PattiKerschmann, RussellBeyer, PaulDittrich, MaryBlock, Geoffrey A.Boyd, Scott D.Parsonnet, JulieChertow, Glenn M.2021-06-11T06:31:07-07:00doi:10.1681/ASN.2021050611hwp:resource-id:jnephrol;32/10/2435American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyimmunology, chronic dialysis, clinical nephrology, immunosuppression, COVID-19, antibody formation, renal dialysis, vaccinationResearch LettersResearch Lettersresearch-article20212021-10-01October 202110.1681/ASN.20210506111046-66731533-34502021-06-11T06:31:07-07:002021-10Journal of the American Society of NephrologyResearch Letters32102435243810.34067/KID.0003512021Tue, 13 Jul 2021 06:19:55 GMT-07:00Impaired Immune Response to SARS-CoV-2 Vaccination in Dialysis Patients and in Kidney Transplant RecipientsKolb, ThiloFischer, SvenjaMüller, LisaLübke, NadineHillebrandt, JonasAndrée, MarcelSchmitz, MichaelSchmidt, ClaudiaKüçükköylü, SeherKoster, LynnKittel, MargaretheWeiland, LeaDreyling, Karl W.Hetzel, GerdAdams, OrtwinSchaal, HeinerIvens, KatrinRump, Lars C.Timm, JörgStegbauer, Johannes2021-07-13T06:19:55-07:00doi:10.34067/KID.0003512021hwp:resource-id:kidney360;2/9/1491American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360transplantation, clinical immunology, COVID-19, humoral immune response, immunity, kidney failure, kidney transplantation, renal insufficiency, SARS-CoV-2 specific antibody, vaccination, virologyOriginal InvestigationTransplantationOriginal InvestigationTransplantationresearch-article20212021-09-3010.34067/KID.00035120212641-76502021-07-13T06:19:55-07:002021-09-30Kidney360Original Investigation291491149810.2215/CJN.04170321Fri, 04 Jun 2021 11:54:31 GMT-07:00COVID-19 among Adults Receiving Home versus In-Center DialysisPerl, JeffreyThomas, DonealTang, YiwenYeung, AngieIp, JaneOliver, Matthew J.Blake, Peter G.2021-06-04T11:54:31-07:00doi:10.2215/CJN.04170321hwp:resource-id:clinjasn;16/9/1410American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, hemodialysis, peritoneal dialysis, mortality risk, research design, cohort studiesResearch LettersResearch Lettersresearch-article20212021-09-01September 202110.2215/CJN.041703211555-90411555-905X2021-06-04T11:54:31-07:002021-09Clinical Journal of the American Society of NephrologyResearch Letters1691410141210.1681/ASN.2021040480Thu, 10 Jun 2021 11:55:37 GMT-07:00Antibody and T Cell Response to SARS-CoV-2 Messenger RNA BNT162b2 Vaccine in Kidney Transplant Recipients and Hemodialysis PatientsBertrand, DominiqueHamzaoui, MouadLemée, VeroniqueLamulle, JulieHanoy, MélanieLaurent, CharlotteLebourg, LudivineEtienne, IsabelleLemoine, MathildeLe Roy, FrankNezam, DorianPlantier, Jean-ChristopheBoyer, OlivierGuerrot, DominiqueCandon, Sophie2021-06-10T11:55:37-07:00doi:10.1681/ASN.2021040480hwp:resource-id:jnephrol;32/9/2147American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, hemodialysis, clinical immunology, COVID-19Rapid CommunicationsRapid Communicationsresearch-article20212021-09-01September 202110.1681/ASN.20210404801046-66731533-34502021-06-10T11:55:37-07:002021-09Journal of the American Society of NephrologyRapid Communications3292147215210.1681/ASN.2021040490Wed, 16 Jun 2021 10:31:16 GMT-07:00Humoral Response after SARS-CoV-2 mRNA Vaccination in a Cohort of Hemodialysis Patients and Kidney Transplant RecipientsDanthu, ClémentHantz, SébastienDahlem, ArthurDuval, MarionBa, BacaryGuibbert, ManonEl Ouafi, ZhourPonsard, SéverineBerrahal, InsafAchard, Jean-MichelBocquentin, FrédériqueAllot, VincentRerolle, Jean-PhilippeAlain, SophieTouré, Fatouma2021-06-16T10:31:16-07:00doi:10.1681/ASN.2021040490hwp:resource-id:jnephrol;32/9/2153American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyvaccine, humoral response, kinetic, hemodialyzed, kidney transplant recipients, COVID-19Rapid CommunicationsRapid Communicationsresearch-article20212021-09-01September 202110.1681/ASN.20210404901046-66731533-34502021-06-16T10:31:16-07:002021-09Journal of the American Society of NephrologyRapid Communications3292153215810.1681/ASN.2020111546Thu, 10 Jun 2021 10:55:33 GMT-07:00Human Kidney Spheroids and Monolayers Provide Insights into SARS-CoV-2 Renal InteractionsOmer, DoritPleniceanu, OrenGnatek, YehuditNamestnikov, MichaelCohen-Zontag, OsnatGoldberg, SanjaFriedman, Yehudit EdenFriedman, NehemyaMandelboim, MichalVitner, Einat B.Achdout, HagitAvraham, RoyZahavy, EranIsraely, TomerMayan, HaimDekel, Benjamin2021-06-10T10:55:33-07:00doi:10.1681/ASN.2020111546hwp:resource-id:jnephrol;32/9/2242American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyrenal tubular epithelial cells, COVID-19, kidney spheroids, acute kidney injury, interferon pathway, SARS-CoV-2, cytopathic damage, kidney stem cells, renal progenitors, human tubular kidney cellsBasic ResearchBasic Researchresearch-article20212021-09-01September 202110.1681/ASN.20201115461046-66731533-34502021-06-10T10:55:33-07:002021-09Journal of the American Society of NephrologyBasic Research3292242225410.1681/ASN.2021020188Mon, 02 Aug 2021 01:46:17 GMT-07:00Hemodialysis Patients Make Long-Lived Antibodies against SARS-CoV-2 that May Be Associated with Reduced ReinfectionBanham, Gemma D.Godlee, AlexandraFaustini, Sian E.Cunningham, Adam F.Richter, AlexHarper, Lorraine,2021-08-02T13:46:17-07:00doi:10.1681/ASN.2021020188hwp:resource-id:jnephrol;32/9/2140American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyhemodialysis, SARS-CoV-2, COVID-19, antibodyResearch LettersResearch Lettersresearch-article20212021-09-01September 202110.1681/ASN.20210201881046-66731533-34502021-08-02T13:46:17-07:002021-09Journal of the American Society of NephrologyResearch Letters3292140214210.34067/KID.0001612021Thu, 20 May 2021 11:51:54 GMT-07:00Association of AKI-D with Urinary Findings and Baseline eGFR in Hospitalized COVID-19 PatientsPatel, Dipal M.Phadke, ManaliDai, FengSimonov, MichaelDahl, Neera K.Kodali, Ravi2021-05-20T11:51:54-07:00doi:10.34067/KID.0001612021hwp:resource-id:kidney360;2/8/1215American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, acute kidney failure, acute kidney injury, COVID-19, dialysis, hematuria, proteinuria, risk factorsOriginal InvestigationAcute Kidney Injury and ICU NephrologyOriginal InvestigationAcute Kidney Injury and ICU Nephrologyresearch-article20212021-08-2610.34067/KID.00016120212641-76502021-05-20T11:51:54-07:002021-08-26Kidney360Original Investigation2812151224b.caplin@ucl.ac.uk10.2215/CJN.03180321Tue, 01 Jun 2021 10:26:55 GMT-07:00Risk of COVID-19 Disease, Dialysis Unit Attributes, and Infection Control Strategy among London In-Center Hemodialysis PatientsCaplin, BenAshby, DamienMcCafferty, KieranHull, RichardAsgari, ElhamFord, Martin L.Cole, NicholasAntonelou, MarilinaBlakey, Sarah A.Srinivasa, VinayBraide-Azikwe, Dandisonba C.B.Roper, TayebaClark, GraceCronin, HelenHayes, Nathan J.Manson, BethiaSarnowski, AlexanderCorbett, RichardBramham, KateLioudaki, EiriniKumar, NicolaFrankel, AndrewMakanjuola, DavidSharpe, Claire C.Banerjee, DebasishSalama, Alan D.,,Elham, AsgariDamien, AshbyDebasish, BanerjeeSarah, BlakeyKate, BramhamRosalind, BrewsterDandisonba, Briade-AzikweHugh, CairnsBen, CaplinParamit, ChowdhuryGrace, ClarkNicholas, ColeRichard, CorbettAndrea, Cove-SmithHelen, CroninMaria, DavariAbigail, DiasKevin, EvansSuzanne, ForbesMartin, FordAndrew, FrankelSahana, GnansampanthanCatriona, GoodladNathan, HayesHeidy, HendraRichard, HullNicola, KumarEirini, LioudakiMarina, LoucaidouDavid, MakanjuolaBethia, MansonKieran, McCaffertyDaniel, McGuinnessAegida, NeradovaMysore, PhanishKatherine, PriceRavi, RajakariarAlex, RankinTayeba, RoperNoam, RothAlan, SalamaAlexander, SarnowskiCassim, SchottClaire, SharpeVinay, SrinivasaDamir, TandaricSujanita, ThyagarajanGisele, VajgelGregor, Young2021-06-01T10:26:55-07:00doi:10.2215/CJN.03180321hwp:resource-id:clinjasn;16/8/1237American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyhemodialysis, COVID-19, infection controlOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20212021-08-01August 202110.2215/CJN.031803211555-90411555-905X2021-06-01T10:26:55-07:002021-08Clinical Journal of the American Society of NephrologyOriginal Articles1688812371141114612461142114810.2215/CJN.17601120Fri, 23 Jul 2021 02:15:11 GMT-07:00Pharmacokinetics of Remdesivir and GS-441524 during PIRRT and Seraph 100 TherapySchmidt, Julius J.Bode-Böger, Stefanie M.Martens-Lobenhoffer, JensHoeper, Marius M.Kielstein, Jan T.2021-07-23T14:15:11-07:00doi:10.2215/CJN.17601120hwp:resource-id:clinjasn;16/8/1256American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, remdesivir, PIRRTResearch LettersResearch Lettersresearch-article20212021-08-01August 202110.2215/CJN.176011201555-90411555-905X2021-07-23T14:15:11-07:002021-08Clinical Journal of the American Society of NephrologyResearch Letters1681256125710.2215/CJN.04080321Mon, 24 May 2021 02:37:49 GMT-07:00Antibody Response to mRNA-1273 SARS-CoV-2 Vaccine in Hemodialysis Patients with and without Prior COVID-19Chan, LiliFuca, NicholasZeldis, EttiCampbell, Kirk N.Shaikh, Aisha2021-05-24T14:37:49-07:00doi:10.2215/CJN.04080321hwp:resource-id:clinjasn;16/8/1258American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, hemodialysis, antibody formation, COVID-19 vaccines, maintenance, RNA, messengerResearch LettersResearch Lettersresearch-article20212021-08-01August 202110.2215/CJN.040803211555-90411555-905X2021-05-24T14:37:49-07:002021-08Clinical Journal of the American Society of NephrologyResearch Letters1681258126010.2215/CJN.17311120Mon, 24 May 2021 02:37:49 GMT-07:00Predictive Approaches for Acute Dialysis Requirement and Death in COVID-19Vaid, AkhilChan, LiliChaudhary, KumardeepJaladanki, Suraj K.Paranjpe, IshanRussak, AdamKia, ArashTimsina, PremLevin, Matthew A.He, John CijiangBöttinger, Erwin P.Charney, Alexander W.Fayad, Zahi A.Coca, Steven G.Glicksberg, Benjamin S.Nadkarni, Girish N.,Charney, AlexJust, Allan C.Glicksberg, BenjaminNadkarni, GirishHuckins, LauraO’Reilly, PaulMiotto, RiccardoFayad, ZahiRussak, Adam J.Rahman, AdeebVaid, AkhilLe Dobbyn, AmandaLeader, AndrewMoscati, ArdenKapoor, ArjunChang, ChristieBellaire, ChristopherCarrion, DanielChaudhry, FayzanRichter, FelixSoultanidis, GeorgiosParanjpe, IshanNabeel, IsmailDe Freitas, JessicaXu, JiayiRush, JohnathanJohnson, KippVemuri, KrishnaChaudhary, KumardeepLepow, LaurenCotter, LiamLiharska, LoraPereanez, MarcoBicak, MesudeDeFelice, NicholasNaik, NidhiBeckmann, NoamNadukuru, RajivO’Hagan, RossZhao, ShanSomani, SulaimanVan Vleck, Tielman T.Mutetwa, TinayeWanyan, TingyiFauveau, ValentinYang, YangLavin, YonitLanksy, AlonaAtreja, AshishDel Valle, DianeMeyer, DaraGolden, EddyeFasihuddin, FarahHsun Wen, HueiRogers, JasonLilly Gutierrez, JenniferWalker, LauraSingh, ManbirDanieletto, MatteoNieves, Melissa A.Zweig, MicolPyzik, RenataFayad, RimaGlowe, PatriciaCalorossi, SharleneKaur, SparshdeepAscolillo, StevenRoa, YovannaLala-Trindade, AnuradhaCoca, Steven G.Percha, BethanySigel, KeithPolak, PazHirten, RobertSwartz, TaliaDo, RonLoos, Ruth J. F.Charney, DennisNestler, EricMurphy, BarbaraReich, DavidBöttinger, ErwinChatani, KumarMartin, GlennNestler, EricKovatch, PatriciaFinkelstein, JosephMurphy, BarbaraBuxbaum, JosephCho, JudyKasarskis, AndrewHorowitz, CarolCordon-Cardo, CarlosSohn, MonicaMartin, GlennGarcia-Sastre, AdolfoBagiella, EmiliaKrammer, FlorianAberg, JudithNarula, JagatWright, RobertLium, ErikWright, RosalindGelijns, AnnetineFuster, ValentinMerad, Miriam2021-05-24T14:37:49-07:00doi:10.2215/CJN.17311120hwp:resource-id:clinjasn;16/8/1158American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysis, machine learning, prediction, AKIOriginal ArticlesAcute Kidney Injury and ICU NephrologyOriginal ArticlesAcute Kidney Injury and ICU Nephrologyresearch-article20212021-08-01August 202110.2215/CJN.173111201555-90411555-905X2021-05-24T14:37:49-07:002021-08Clinical Journal of the American Society of NephrologyOriginal Articles1681158116810.1681/ASN.2020111606Thu, 03 Jun 2021 10:55:07 GMT-07:00Racial and Neighborhood-Level Disparities in COVID-19 Incidence among Patients on Hemodialysis in New York CityTummalapalli, Sri LekhaSilberzweig, JeffreyCukor, DanielLin, Jonathan T.Barbar, TarekLiu, YaoKim, KwanParker, Thomas S.Levine, Daniel M.Ibrahim, Said A.2021-06-03T10:55:07-07:00doi:10.1681/ASN.2020111606hwp:resource-id:jnephrol;32/8/2048American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, hemodialysis, disparities, social determinants of healthClinical ResearchClinical Researchresearch-article20212021-08-01August 202110.1681/ASN.20201116061046-66731533-34502021-06-03T10:55:07-07:002021-08Journal of the American Society of NephrologyClinical Research32882048i2056i10.1681/ASN.2021030387Fri, 02 Jul 2021 08:30:07 GMT-07:00Antibody Status, Disease History, and Incidence of SARS-CoV-2 Infection Among Patients on Chronic DialysisCohen, Dena E.Sibbel, ScottMarlowe, GilbertBludorn, KelseyMiller, DawnKelley, TaraConnaire, JeffreyYoung, AmyTentori, FrancescaBrunelli, Steven M.2021-07-02T08:30:07-07:00doi:10.1681/ASN.2021030387hwp:resource-id:jnephrol;32/8/1880American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, hemodialysis, immunityRapid CommunicationsRapid Communicationsresearch-article20212021-08-01August 202110.1681/ASN.20210303871046-66731533-34502021-07-02T08:30:07-07:002021-08Journal of the American Society of NephrologyRapid Communications3281880188610.1681/ASN.2021020161Tue, 06 Jul 2021 11:35:56 GMT-07:00Presence of SARS-CoV-2 Antibodies in Spent Peritoneal DialysateWang, XiaolingGrobe, NadjaPatel, AmrishSharma, ShuchitaUribarri, JaimeKotanko, Peter2021-07-06T11:35:56-07:00doi:10.1681/ASN.2021020161hwp:resource-id:jnephrol;32/8/1865American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyperitoneal dialysis, antibody, SARS-CoV-2, COVID-19Research LettersResearch Lettersresearch-article20212021-08-01August 202110.1681/ASN.20210201611046-66731533-34502021-07-06T11:35:56-07:002021-08Journal of the American Society of NephrologyResearch Letters32818651867AKI frequently occurs in patients with COVID-19, and kidney injury severe enough to require RRT is a common complication among patients who are critically ill. During the surge of the pandemic, there was a high demand for dialysate for continuous RRT, and this increase in demand, coupled with vulnerabilities in the supply chain, necessitated alternative approaches, including internal production of dialysate. Using a standard hemodialysis machine and off-the-shelf supplies, as per Food and Drug Administration guidelines, we developed a method for on-site dialysate production that is adaptable and can be used to fill multiple bags at once. The use of a central reverse osmosis unit, dedicated hemodialysis machine, sterile bags with separate ports for fill and use, and frequent testing will ensure stability, sterility, and—therefore—safety of the produced dialysate. The dialysate made in house was tested and it showed both stability and sterility for at least 30 hours. This detailed description of our process for generating dialysate can serve as a guide for other programs experiencing similar vulnerabilities in the demand versus supply of dialysate.10.34067/KID.0000652021Fri, 14 May 2021 11:46:11 GMT-07:00Protocol for Local On-Site Dialysate Production for Continuous Renal Replacement Therapy during the COVID-19 PandemicAKI frequently occurs in patients with COVID-19, and kidney injury severe enough to require RRT is a common complication among patients who are critically ill. During the surge of the pandemic, there was a high demand for dialysate for continuous RRT, and this increase in demand, coupled with vulnerabilities in the supply chain, necessitated alternative approaches, including internal production of dialysate. Using a standard hemodialysis machine and off-the-shelf supplies, as per Food and Drug Administration guidelines, we developed a method for on-site dialysate production that is adaptable and can be used to fill multiple bags at once. The use of a central reverse osmosis unit, dedicated hemodialysis machine, sterile bags with separate ports for fill and use, and frequent testing will ensure stability, sterility, and—therefore—safety of the produced dialysate. The dialysate made in house was tested and it showed both stability and sterility for at least 30 hours. This detailed description of our process for generating dialysate can serve as a guide for other programs experiencing similar vulnerabilities in the demand versus supply of dialysate.Moses, Andrew A.Stevens, Jacob S.Fine, DerekCarrera, RobertLi, AlinaParikh, Chirag R.Mohan, Sumit2021-05-14T11:46:11-07:00doi:10.34067/KID.0000652021hwp:resource-id:kidney360;2/7/1152American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, continuous kidney replacement, continuous renal replacement therapy, COVID-19, dialysate, dialysate production, disaster planningInnovative Technology and MethodologyAcute Kidney Injury and ICU NephrologyInnovative Technology and MethodologyAcute Kidney Injury and ICU Nephrologyresearch-article20212021-07-2910.34067/KID.00006520212641-76502021-05-14T11:46:11-07:002021-07-29Kidney360Innovative Technology and Methodology271152115510.34067/KID.0001562021Tue, 18 May 2021 01:29:37 GMT-07:00Expression of ACE2 in the Intact and Acutely Injured KidneyNath, Karl A.Singh, Raman DeepGrande, Joseph P.Garovic, Vesna D.Croatt, Anthony J.Ackerman, Allan W.Barry, Michael A.Agarwal, Anupam2021-05-18T13:29:37-07:00doi:10.34067/KID.0001562021hwp:resource-id:kidney360;2/7/1095American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, angiotensin-converting enzyme 2, basic science, heme oxygenase, ischemia reperfusion, lipopolysaccharide, peptidyl-dipeptidase A, urinary tract obstructionOriginal investigationAcute Kidney Injury and ICU NephrologyOriginal investigationAcute Kidney Injury and ICU Nephrologyresearch-article20212021-07-2910.34067/KID.00015620212641-76502021-05-18T13:29:37-07:002021-07-29Kidney360Original investigation271095110610.34067/KID.0002592021Mon, 17 May 2021 01:38:21 GMT-07:00Increased Mortality Associated with Hypermagnesemia in Severe COVID-19 IllnessStevens, Jacob S.Moses, Andrew A.Nickolas, Thomas L.Husain, Syed AliMohan, Sumit2021-05-17T13:38:21-07:00doi:10.34067/KID.0002592021hwp:resource-id:kidney360;2/7/1087American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acid/base and electrolyte disorders, coronavirus, COVID-19, hypermagnesemia, magnesium, rhabdomyolysis, SARS-CoV-2Original InvestigationAcid/Base and Electrolyte DisordersOriginal InvestigationAcid/Base and Electrolyte Disordersresearch-article20212021-07-2910.34067/KID.00025920212641-76502021-05-17T13:38:21-07:002021-07-29Kidney360Original Investigation271087109410.34067/KID.0002112021Thu, 22 Apr 2021 01:34:55 GMT-07:00Living Organ Donor Perspectives and Sources of Hesitancy about COVID-19 VaccinesHarhay, Meera N.Klassen, Ann C.Zaidi, HasanMittelman, MichaelBertha, RebeccaMannon, Roslyn B.Lentine, Krista L.2021-04-22T13:34:55-07:00doi:10.34067/KID.0002112021hwp:resource-id:kidney360;2/7/1132American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360transplantation, COVID-19, dysuria, kidney transplant, liver transplant, living donor, organ donation, vaccineOriginal investigationTransplantationOriginal investigationTransplantationresearch-article20212021-07-2910.34067/KID.00021120212641-76502021-04-22T13:34:55-07:002021-07-29Kidney360Original investigation271132114010.34067/KID.0006852020Thu, 06 May 2021 01:38:52 GMT-07:00Outcomes among Hospitalized Chronic Kidney Disease Patients with COVID-19Khatri, MineshCharytan, David M.Parnia, SamPetrilli, Christopher M.Michael, JeffreyLiu, DavidTatapudi, VasishtaJones, SimonBenstein, JudithHorwitz, Leora I.2021-05-06T13:38:52-07:00doi:10.34067/KID.0006852020hwp:resource-id:kidney360;2/7/1107American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360chronic kidney disease, CKD, COVID-19, dialysis, end stage renal disease, mortality, SARS-CoV-2Original InvestigationChronic Kidney DiseaseOriginal InvestigationChronic Kidney Diseaseresearch-article20212021-07-2910.34067/KID.00068520202641-76502021-05-06T13:38:52-07:002021-07-29Kidney360Original Investigation271107111410.34067/KID.0002172021Wed, 14 Apr 2021 11:50:46 GMT-07:00Evidence for SARS-CoV-2 Spike Protein in the Urine of COVID-19 PatientsGeorge, SantoshPal, Anasuya ChattopadhyayGagnon, JacquelineTimalsina, SushmaSingh, PallaviVydyam, PratapMunshi, MuhammadChiu, Joy E.Renard, IsalineHarden, Christina A.Ott, Isabel M.Watkins, Anne E.Vogels, Chantal B.F.Lu, PeiwenTokuyama, MariaVenkataraman, ArvindCasanovas-Massana, ArnauWyllie, Anne L.Rao, VeenaCampbell, MelissaFarhadian, Shelli F.Grubaugh, Nathan D.Dela Cruz, Charles S.Ko, Albert I.Berna Perez, Amalia Z.Akaho, Elikplim H.Moledina, Dennis G.Testani, JeffreyJohn, Audrey R.Ledizet, MichelMamoun, Choukri Ben,2021-04-14T11:50:46-07:00doi:10.34067/KID.0002172021hwp:resource-id:kidney360;2/6/924American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, body fluids, coronavirus, COVID-19, enzyme-linked immunosorbent assay, SARS-CoV-2, spike glycoprotein, spike protein, viral envelope proteinsOriginal InvestigationAcute Kidney Injury and ICU NephrologyOriginal InvestigationAcute Kidney Injury and ICU Nephrologyresearch-article20212021-06-2410.34067/KID.00021720212641-76502021-04-14T11:50:46-07:002021-06-24Kidney360Original Investigation2692493610.2215/CJN.18961220Fri, 04 Jun 2021 11:54:31 GMT-07:00Renin-Angiotensin System Blockers and the Risk of COVID-19–Related Mortality in Patients with Kidney FailureSoler, Maria JoseNoordzij, MarliesAbramowicz, Danielde Arriba, GabrielBasile, Carlovan Buren, MarjolijnCovic, AdrianCrespo, MartaDuivenvoorden, RaphaëlMassy, Ziad A.Ortiz, AlbertoSanchez, J. EmilioPetridou, EmilyStevens, KateWhite, ColinVart, PriyaGansevoort, Ron T.,,van der Net, Jeroen B.Essig, Mariedu Buf-Vereijken, Peggy W.G.van Ginneken, BettyMaas, NandaVogt, Liffertvan Jaarsveld, Brigit C.Jager, Kitty J.Bemelman, Frederike J.Klingenberg-Salahova, FarahHeenan-Vos, FrederiekVervloet, Marc G.Nurmohamed, AzamVerhofstede, SabineMaoujoud, OmarMalfait, ThomasFialova, JanaMelilli, EdoardoFavà, AlexandreCruzado, Josep M.Perez, Nuria MonteroLips, JoyKrepel, HarmenAdilovic, HarunHengst, MaaikeRydzewski, AndrzejGellert, RyszardOliveira, JoãoAlferes, Daniela G.Zakharova, Elena V.Ambuehl, Patrice MaxWinzeler, RebeccaLepeytre, FannyRabaté, ClémentineRostoker, GuyMarques, SofiaAzasevac, TijanaKaticic, DajanaDam, Marc tenKrüger, ThiloBrzosko, Szymonvan Zanen, A.L.Logtenberg, Susan J.J.Fricke, LutzSlebe, Jeroen J.P.Kemlin, Delphinevan de Wetering, JacquelineReinders, Marlies E.J.Eiselt, JaromirKielberger, LukasEl-Wakil, Hala S.ElHafeez, Samar AbdCanal, CristinaFacundo, CarmeRamos, Ana M.Debska-Slizien, AlicjaVeldhuizen, Nicoline M.H.Panagoutsos, StylianosMatceac, IrinaNistor, IonutCordos, MonicaGroeneveld, J.H.MJousma, JolandaDiekmann, FritzPereira, Tiago AssisSantos, Augusto Cesar S.Arias-Cabrales, CarlosLlinàs-Mallol, LauraBuxeda, AnnaTàrrega, Carla BurballaRedondo-Pachon, DoloresArenas Jimenez, Maria DoloresHofstra, Julia M.Franco, AntonioArroyo, DavidRodríguez-Ferrero, Maria LuisaManzanos, Sagrario BaldaSosa Barrios, R. HaridianLemahieu, WimBartelet, KarlijnDirim, Ahmet BurakDemir, ErolSever, Mehmet SukruTurkmen, AydinHollander, Daan A.M.J.Büttner, Stefande Vries, Aiko P.J.Meziyerh, Soufianvan der Helm, DannyMallat, MarkoBouwsma, HannekeSridharan, SivakumarPetruliene, KristinaMaloney, Sharon-RoseVerberk, Irisvan der Sande, Frank M.Christiaans, Maarten H.L.Hemmelder, MarcDi Luca, MarinaTuğlular, Serhan Z.Beerenhout, CharlesLuik, Peter T.Kerschbaum, JuliaTiefenthaler, MartinWatschinger, BrunoAdema, Aaltje Y.Stepanov, Vadim A.Zulkarnaev, Alexey B.Turkmen, KultiginFliedner, AnselmÅsberg, AndersMjoen, GeirMiyasato, Hitoshide Fijter, Carola W.H.Pini, Stefanode Biase, ConsueloHilbrands, LuukKerckhoffs, Angelevan de Logt, Anne ElsMaas, RutgerLebedeva, OlgaLopez, VeronicaReichert, Louis J.M.Verhave, JacobienTitov, DenisParshina, Ekaterina V.Zanoli, LucaMarcantoni, Carmelitavan Gils-Verrij, Liesbeth E.A.Harty, John C.Meurs, MarleenMyslak, MarekBattaglia, YuriLentini, Paoloden Deurwaarder, EdwinStendahl, MariaRahimzadeh, HormatSchouten, MarcelRychlik, IvanCabezas-Reina, Carlos J.Roca, Ana MariaNauta, FerdauGoffin, EricKanaan, NadaLabriola, LauraDevresse, ArnaudDiaz-Mareque, AnabelCoca, ArmandoMeijers, Björn K.I.Naesens, MaartenKuypers, DirkDesschans, BrunoTonnerlier, AnneliesWissing, Karl M.Dedinska, IvanaPessolano, GiuseppinaGandolfini, IlariaMaggiore, UmbertoMalik, ShafiPapachristou, EvangelosFranssen, Casper F.M.Berger, Stefan P.Meijer, EstherSanders, Jan Stephan F.Ponikvar, Jadranka ButurovićPernat, Andreja MarnKovac, DamjanArnol, MihaEkart, RobertAbrahams, Alferso C.Molenaar, Femke M.van Zuilen, Arjan D.Meijvis, Sabine C.A.Dolmans, HelmaEsposito, PasqualeKrzesinski, Jean-MarieBarahira, Jean DamacèneGallieni, MaurizioMartin-Moreno, Paloma LeticiaGuglielmetti, GabrieleGuzzo, GabriellaLuik, Antinus J.van Kuijk, Willi H.M.Stikkelbroeck, Lonneke W.H.Hermans, Marc M.H.Rimsevicius, LaurynasRighetti, MarcoIslam, MahmudBraak, Nicole Heitink-ter2021-06-04T11:54:31-07:00doi:10.2215/CJN.18961220hwp:resource-id:clinjasn;16/7/1061American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, renin angiotensin system, dialysis, kidney transplantation, kidney failureOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20212021-07-01July 202110.2215/CJN.189612201555-90411555-905X2021-06-04T11:54:31-07:002021-07Clinical Journal of the American Society of NephrologyOriginal Articles16771061100210721004The COVID-19 pandemic continues to strain health care systems and drive shortages in medical supplies and equipment around the world. Resource allocation in times of scarcity requires transparent, ethical frameworks to optimize decision making and reduce health care worker and patient distress. The complexity of allocating dialysis resources for both patients receiving acute and maintenance dialysis has not previously been addressed. Using a rapid, collaborative, and iterative process, BC Renal, a provincial network in Canada, engaged patients, doctors, ethicists, administrators, and nurses to develop a framework for addressing system capacity, communication challenges, and allocation decisions. The guiding ethical principles that underpin this framework are (1) maximizing benefits, (2) treating people fairly, (3) prioritizing the worst-off individuals, and (4) procedural justice. Algorithms to support resource allocation and triage of patients were tested using simulations, and the final framework was reviewed and endorsed by members of the provincial nephrology community. The unique aspects of this allocation framework are the consideration of two diverse patient groups who require dialysis (acute and maintenance), and the application of two allocation criteria (urgency and prognosis) to each group in a sequential matrix. We acknowledge the context of the Canadian health care system, and a universal payer in which this framework was developed. The intention is to promote fair decision making and to maintain an equitable reallocation of limited resources for a complex problem during a pandemic.10.2215/CJN.07460520Mon, 08 Feb 2021 09:47:52 GMT-08:00Balancing the Needs of Acute and Maintenance Dialysis Patients during the COVID-19 PandemicThe COVID-19 pandemic continues to strain health care systems and drive shortages in medical supplies and equipment around the world. Resource allocation in times of scarcity requires transparent, ethical frameworks to optimize decision making and reduce health care worker and patient distress. The complexity of allocating dialysis resources for both patients receiving acute and maintenance dialysis has not previously been addressed. Using a rapid, collaborative, and iterative process, BC Renal, a provincial network in Canada, engaged patients, doctors, ethicists, administrators, and nurses to develop a framework for addressing system capacity, communication challenges, and allocation decisions. The guiding ethical principles that underpin this framework are (1) maximizing benefits, (2) treating people fairly, (3) prioritizing the worst-off individuals, and (4) procedural justice. Algorithms to support resource allocation and triage of patients were tested using simulations, and the final framework was reviewed and endorsed by members of the provincial nephrology community. The unique aspects of this allocation framework are the consideration of two diverse patient groups who require dialysis (acute and maintenance), and the application of two allocation criteria (urgency and prognosis) to each group in a sequential matrix. We acknowledge the context of the Canadian health care system, and a universal payer in which this framework was developed. The intention is to promote fair decision making and to maintain an equitable reallocation of limited resources for a complex problem during a pandemic.Carson, Rachel C.Forzley, BrianThomas, SarahPreto, NinaHargrove, GayleneVirani, AliceAntonsen, JohnBrown, MelanieCopland, MichaelMichaud, MarieSingh, AnuragLevin, Adeera2021-02-08T09:47:52-08:00doi:10.2215/CJN.07460520hwp:resource-id:clinjasn;16/7/1122American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, chronic disease, renal replacement therapy, acute care, ethics, acute kidney injury, triageInvited FeaturesInvited Featuresother20212021-07-01July 202110.2215/CJN.074605201555-90411555-905X2021-02-08T09:47:52-08:002021-07Clinical Journal of the American Society of NephrologyInvited Features1671122113010.2215/CJN.03700321Mon, 24 May 2021 02:37:49 GMT-07:00Early Humoral Responses of Hemodialysis Patients after COVID-19 Vaccination with BNT162b2Speer, ClaudiusGöth, DanielBenning, LouiseBuylaert, MirabelSchaier, MatthiasGrenz, JuliaNusshag, ChristianKälble, FlorianKreysing, MartinReichel, PaulaTöllner, MaximilianHidmark, AsaPonath, GeraldSchnitzler, PaulZeier, MartinSüsal, CanerMorath, ChristianKlein, Katrin2021-05-24T14:37:49-07:00doi:10.2215/CJN.03700321hwp:resource-id:clinjasn;16/7/1073American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyvaccination, COVID-19, SARS-CoV-2, dialysis, humoral response, hemodialysisOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20212021-07-01July 202110.2215/CJN.037003211555-90411555-905X2021-05-24T14:37:49-07:002021-07Clinical Journal of the American Society of NephrologyOriginal Articles16771073996108299810.2215/CJN.00330121Mon, 07 Jun 2021 02:18:37 GMT-07:00Prevalence of SARS-CoV-2-IgG Antibodies in Children with CKD or ImmunosuppressionMorello, WilliamMastrangelo, AntonioGuzzo, IsabellaCusinato, LisaAnnicchiarico Petruzzelli, LuigiBenevenuta, ChiaraMartelli, LauraDall’Amico, RobertoVianello, Federica AlessandraPuccio, GiuseppeMassella, LauraBenetti, ElisaPecoraro, CarminePeruzzi, LiciaMontini, Giovanni,,Peruzzi, LiciaPetruzzelli, Luigi AnnicchiaricoBecherucci, FrancescaBenetti, ElisaBenevenuta, ChiaraBrugnara, MilenaCasadio, LucaChimenz, RobertoConti, GiovanniCorrado, CiroD’Agostino, VivianaDall’Amico, RobertoGianoglio, BrunoGiordano, MarioGualeni, ChiaraGuarino, StefanoGuzzo, IsabellaLa Manna, AngelaLa Scola, ClaudioMartelli, LauraMassella, LauraMastrangelo, AntonioMaterassi, MarcoMontini, GiovanniMorello, WilliamPani, AntonelloPapalia, TeresaPasini, AndreaPecoraro, CarminePelliccia, PiernicolaPennesi, MarcoPugliese, FabrizioRatsch, Ilse MariaRomagnani, PaolaRoperto, Rosa MariaTamburello, ChiaraVergine, GianlucaVergori, AntonioVianello, Federica AlessandraVidal, Enrico2021-06-07T14:18:37-07:00doi:10.2215/CJN.00330121hwp:resource-id:clinjasn;16/7/1097American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, SARS-CoV-2 IgG, CKD, immunosuppression, children, chronic kidney disease, idiopathic nephrotic syndromeResearch LetterResearch Letterresearch-article20212021-07-01July 202110.2215/CJN.003301211555-90411555-905X2021-06-07T14:18:37-07:002021-07Clinical Journal of the American Society of NephrologyResearch Letter1671097109910.2215/CJN.03500321Tue, 06 Apr 2021 07:54:43 GMT-07:00Humoral Response to the Pfizer BNT162b2 Vaccine in Patients Undergoing Maintenance HemodialysisGrupper, AyeletSharon, NechamaFinn, TalyaCohen, RegevIsrael, MeitalAgbaria, AmirRechavi, YoavSchwartz, Idit F.Schwartz, DoronLellouch, YonatanShashar, Moshe2021-04-06T07:54:43-07:00doi:10.2215/CJN.03500321hwp:resource-id:clinjasn;16/7/1037American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, vaccine, hemodialysis, BNT162 vaccine, renal dialysisOriginal ArticlesClinical NephrologyOriginal ArticlesClinical Nephrologyresearch-article20212021-07-01July 202110.2215/CJN.035003211555-90411555-905X2021-04-06T07:54:43-07:002021-07Clinical Journal of the American Society of NephrologyOriginal Articles16771037996104299810.34067/KID.0001282021Wed, 21 Apr 2021 06:02:44 GMT-07:00SARS-CoV-2 Infection Risk Factors among Maintenance Hemodialysis Patients and Health Care Personnel In Outpatient Hemodialysis CentersGandra, SumanthLi, TingtingReske, Kimberly A.Dang, Na LeFarnsworth, Christopher W.Hock, Karl G.Miller, CandaceOlsen, Margaret A.Kwon, Jennie H.Warren, David K.Fraser, Victoria J.2021-04-21T06:02:44-07:00doi:10.34067/KID.0001282021hwp:resource-id:kidney360;2/6/996American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, delivery of health care, ESRD, health personnel, hemodialysis, outpatients, risk factors, SARS-CoV-2Brief CommunicationDialysisBrief CommunicationDialysisresearch-article20212021-06-2410.34067/KID.00012820212641-76502021-04-21T06:02:44-07:002021-06-24Kidney360Brief Communication26996100110.34067/KID.0007282020Wed, 28 Apr 2021 12:29:36 GMT-07:00Autosomal Dominant Polycystic Kidney Disease Does Not Significantly Alter Major COVID-19 Outcomes among VeteransCui, XiangqinGallini, Julia W.Jasien, Christine L.Mrug, Michal2021-04-28T12:29:36-07:00doi:10.34067/KID.0007282020hwp:resource-id:kidney360;2/6/983American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360cystic kidney disease, chronic kidney disease, coronavirus disease 2019, COVID-19, hospital admission, ICU admission, kidney failure, mortality, polycystic kidney disease, SARS-CoV-2, ventilator, veteransBrief CommunicationCystic Kidney DiseaseBrief CommunicationCystic Kidney Diseaseresearch-article20212021-06-2410.34067/KID.00072820202641-76502021-04-28T12:29:36-07:002021-06-24Kidney360Brief Communication2698398810.1681/ASN.2020111653Wed, 09 Jun 2021 01:22:33 GMT-07:00Epidemiology and Outcomes of COVID-19 in Home Dialysis Patients Compared with In-Center Dialysis PatientsHsu, Caroline M.Weiner, Daniel E.Aweh, GideonSalenger, PageJohnson, Doug S.Lacson, Eduardo2021-06-09T13:22:33-07:00doi:10.1681/ASN.2020111653hwp:resource-id:jnephrol;32/7/1569American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologychronic dialysis, chronic kidney disease, epidemiology and outcomes, ESKD, peritoneal dialysis, risk factors, SARS-CoV-2, COVID-19Research lettersResearch lettersletter20212021-07-01July 202110.1681/ASN.20201116531046-66731533-34502021-06-09T13:22:33-07:002021-07Journal of the American Society of NephrologyResearch letters3271569157310.1681/ASN.2021010104Thu, 29 Apr 2021 04:53:52 GMT-07:00SARS-CoV-2 Vaccine Acceptability in Patients on Hemodialysis: A Nationwide SurveyGarcia, PabloMontez-Rath, Maria E.Moore, HeatherFlotte, JohnieFults, ChrisBlock, Martha S.Han, JialinDittrich, MaryParsonnet, JulieChertow, Glenn M.Block, Geoffrey A.Anand, Shuchi2021-04-29T04:53:52-07:00doi:10.1681/ASN.2021010104hwp:resource-id:jnephrol;32/7/1575American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologydialysis, vaccine, SARS-CoV-2, ESKD, COVID-19Rapid CommunicationRapid Communicationresearch-article20212021-07-01July 202110.1681/ASN.20210101041046-66731533-34502021-04-29T04:53:52-07:002021-07Journal of the American Society of NephrologyRapid Communication3271575158110.2215/CJN.01890221Fri, 11 Jun 2021 12:06:56 GMT-07:00Vaccines and Disease Relapses in Children with Nephrotic SyndromeAngeletti, AndreaBruschi, MaurizioBianchin, SilviaBonato, IreneMontobbio, CarolinaVerrina, EnricoLugani, FrancescaCravedi, PaoloGhiggeri, Gian Marco2021-06-11T12:06:56-07:00doi:10.2215/CJN.01890221hwp:resource-id:clinjasn;16/6/937American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyidiopathic nephrotic syndrome, vaccines, rituximab, COVID-19, pediatric nephrology, steroid dependent nephrotic syndrome, children, nephrotic syndromeResearch LettersResearch Lettersresearch-article20212021-06-01June 202110.2215/CJN.018902211555-90411555-905X2021-06-11T12:06:56-07:002021-06Clinical Journal of the American Society of NephrologyResearch Letters16693793810.1681/ASN.2021010009Thu, 08 Apr 2021 07:35:09 GMT-07:00Initial Effects of COVID-19 on Patients with ESKDWeinhandl, Eric D.Wetmore, James B.Peng, YiLiu, JiannongGilbertson, David T.Johansen, Kirsten L.2021-04-08T07:35:09-07:00doi:10.1681/ASN.2021010009hwp:resource-id:jnephrol;32/6/1444American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, dialysis, hospitalization, mortality, transplantationClinical EpidemiologyClinical Epidemiologyresearch-article20212021-06-01June 202110.1681/ASN.20210100091046-66731533-34502021-04-08T07:35:09-07:002021-06Journal of the American Society of NephrologyClinical Epidemiology32661444i1453i10.2215/CJN.16281020Mon, 29 Mar 2021 10:58:19 GMT-07:00Association between Postmortem Kidney Biopsy Findings and Acute Kidney Injury from Patients with SARS-CoV-2 (COVID-19)Rivero, JesúsMerino-López, MaribelOlmedo, RossanaGarrido-Roldan, RubénMoguel, BernardoRojas, GustavoChavez-Morales, AlfonsoAlvarez-Maldonado, PabloDuarte-Molina, PabloCastaño-Guerra, RodolfoRuiz-Lopez, Ivon KarinaSoria-Castro, ElizabethLuna, CesarBonilla-Méndez, AlejandroBaranda, FranciscoZabal, CarlosMadero, MagdalenaValdez-Ortiz, RafaelSoto-Abraham, Ma. VirgiliaVazquez-Rangel, Armando2021-03-29T10:58:19-07:00doi:10.2215/CJN.16281020hwp:resource-id:clinjasn;16/5/685American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologypostmortem, kidney biopsy, acute kidney injury, SARS-CoV-2, COVID-19Original ArticlesAcute Kidney Injury and ICU NephrologyOriginal ArticlesAcute Kidney Injury and ICU Nephrologyresearch-article20212021-05-08May 08, 202110.2215/CJN.162810201555-90411555-905X2021-03-29T10:58:19-07:002021-05-08Clinical Journal of the American Society of NephrologyOriginal Articles16568569310.2215/CJN.13820820Mon, 08 Feb 2021 09:47:53 GMT-08:00Outcomes of COVID-19 in CKD PatientsPakhchanian, HaigRaiker, RahulMukherjee, AmritaKhan, AhmadSingh, ShailendraChatterjee, Arka2021-02-08T09:47:53-08:00doi:10.2215/CJN.13820820hwp:resource-id:clinjasn;16/5/785American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, chronic kidney disease, end stage kidney disease, Electronic Health RecordsResearch LettersResearch Lettersletter20212021-05-08May 08, 202110.2215/CJN.138208201555-90411555-905X2021-02-08T09:47:53-08:002021-05-08Clinical Journal of the American Society of NephrologyResearch Letters16578578610.1681/ASN.2020111618Fri, 26 Feb 2021 10:17:37 GMT-08:00Kinetics of Anti–SARS-CoV-2 IgG Antibodies in Hemodialysis Patients Six Months after InfectionSakhi, HamzaDahmane, DjamalAttias, PhilippeKofman, ThomasBouvier, MagaliLapidus, NathanaelFourati, SlimEl Karoui, Khalil,,Audard, VincentBentaarit, BoutheinaBoueilh, AnnaGallien, SébastienGrimbert, PhilippeHüe, SophieJoher, NizarJouan, NarindraLamriben, LarbiLelièvre, Jean-DanielLepeule, RaphaëlMahévas, MatthieuMatignon, MarieMelica, GiovannaOniszczuk, JuliePawlotsky, Jean-MichelStehlé, ThomasVindrios, WilliamWemmert, Charlotte2021-02-26T10:17:37-08:00doi:10.1681/ASN.2020111618hwp:resource-id:jnephrol;32/5/1033American Society of NephrologyCopyright © 2021 by the American Society of Nephrology This is an Open Access article: American Society of NephrologyJournal of the American Society of Nephrologyhemodialysis, SARS-CoV-2, serology, SARS-CoV-2 antibody, COVID-19Rapid CommunicationRapid Communicationresearch-article20212021-05-03May 202110.1681/ASN.20201116181046-66731533-34502021-02-26T10:17:37-08:002021-05-03Journal of the American Society of NephrologyRapid Communication32551033i1036i10.34067/KID.0006992020Fri, 12 Feb 2021 09:23:36 GMT-08:00COVID-19–associated Nephropathy Includes Tubular Necrosis and Capillary Congestion, with Evidence of SARS-CoV-2 in the NephronBouquegneau, AntoineErpicum, PaulineGrosch, StéphanieHabran, LionelHougrand, OlivierHuart, JustineKrzesinski, Jean-MarieMisset, BenoîtHayette, Marie-PierreDelvenne, PhilippeBovy, ChristopheKylies, DominikHuber, Tobias B.Puelles, Victor G.Delanaye, PierreJouret, Francois2021-02-12T09:23:36-08:00doi:10.34067/KID.0006992020hwp:resource-id:kidney360;2/4/639American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, histology, immunostaining, in situ hybridization, kidney, SARS-CoV-2Original InvestigationClinical NephrologyOriginal InvestigationClinical Nephrologyresearch-article20212021-04-2910.34067/KID.00069920202641-76502021-02-12T09:23:36-08:002021-04-29Kidney360Original Investigation2463965210.34067/KID.0005372020Wed, 03 Feb 2021 09:27:12 GMT-08:00AKI in COVID-19–Associated Multisystem Inflammatory Syndrome in Children (MIS-C)Lipton, MarissaMahajan, RuchiKavanagh, CatherineShen, CarolBatal, IbrahimDogra, SamritiJain, Namrata G.Lin, FangmingUy, Natalie S.2021-02-03T09:27:12-08:00doi:10.34067/KID.0005372020hwp:resource-id:kidney360;2/4/611American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, acute kidney injury, AKI, child, COVID-19, MIS-C, pediatric multisystem inflammatory disease, pediatric nephrologyOriginal InvestigationAcute Kidney Injury and ICU NephrologyOriginal InvestigationAcute Kidney Injury and ICU Nephrologyresearch-article20212021-04-2910.34067/KID.00053720202641-76502021-02-03T09:27:12-08:002021-04-29Kidney360Original Investigation2461161810.34067/KID.0007322020Fri, 26 Feb 2021 12:04:31 GMT-08:00AKI in Hospitalized Patients with COVID-19 and Seasonal Influenza: A Comparative AnalysisBhasin, BhavnaVeitla, VineetDawson, Aprill Z.Garacci, ZhupingSturgill, DanielOzieh, Mukoso N.Regner, Kevin R.2021-02-26T12:04:31-08:00doi:10.34067/KID.0007322020hwp:resource-id:kidney360;2/4/619American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, acute kidney injury, COVID-19, influenza, mortality, renal replacement therapyOriginal InvestigationAcute Kidney Injury and ICU 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NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, antibodies, COVID-19, end stage renal disease, hemodialysis, outpatients, SARS-CoV-2Original InvestigationsDialysisOriginal InvestigationsDialysisresearch-article20212021-02-2510.34067/KID.00062920202641-76502020-12-09T14:28:11-08:002021-02-25Kidney360Original Investigations2226326910.2215/CJN.07440520Fri, 18 Sep 2020 10:25:18 GMT-07:00Characteristics of Acute Kidney Injury in Hospitalized COVID-19 Patients in an Urban Academic Medical CenterLee, John R.Silberzweig, JeffreyAkchurin, OlehChoi, Mary E.Srivatana, VeshLin, JonathanLiu, FrankMalha, LineLubetzky, MichelleDadhania, Darshana M.Shankaranarayanan, DivyaShimonov, DaniilNeupane, SanjaySalinas, ThaliaBhasin, AartiVarma, EllyLeuprecht, LorenzGerardine, SupriyaLamba, PerolaGoyal, ParagCaliendo, EricTiase, VictoriaSharma, RahulPark, Joel C.Steel, Peter A.D.Suthanthiran, ManikkamZhang, 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NephrologyKidney360hypertension, ACE inhibitors, angiotensin II receptor blocker, cohort studies, COVID-19, hospitalization, hypertension, inflammation, renin angiotensin system, respirationOriginal InvestigationsHypertensionOriginal InvestigationsHypertensionresearch-article20202020-08-2710.34067/KID.00037920202641-76502020-06-22T13:37:01-07:002020-08-27Kidney360Original Investigations1880180910.34067/KID.0003352020Tue, 02 Jun 2020 02:13:45 GMT-07:00Urinary Sediment Microscopy in Acute Kidney Injury Associated with COVID-19Hernandez-Arroyo, Cesar F.Varghese, VipinMohamed, Muner M.B.Velez, Juan Carlos Q.2020-06-02T14:13:45-07:00doi:10.34067/KID.0003352020hwp:resource-id:kidney360;1/8/819American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360Clinical Nephrology, Acute Kidney Injury, acute tubular injury, acute tubular necrosis, coronavirus, COVID-19, diagnosis, granular casts, Microscopy, SARS-CoV-2, urine sedimentBrief CommunicationsBrief 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the American Society of NephrologyJournal of the American Society of Nephrologycollapsing glomerulopathy, APOL1, kidney biopsy, SARS-CoV-2, nephrotic, COVID-19Rapid CommunicationRapid Communicationresearch-article20202020-08-01August 202010.1681/ASN.20200505581046-66731533-34502020-06-19T10:06:04-07:002020-08Journal of the American Society of NephrologyRapid Communication3181688169510.1681/ASN.2020050599Tue, 16 Jun 2020 07:39:41 GMT-07:00Acute Start Peritoneal Dialysis during the COVID-19 Pandemic: Outcomes and ExperiencesEl Shamy, OsamaPatel, NiraleeAbdelbaset, Mohamed HalimChenet, LindaTokita, JojiLookstein, RobertLee, David S.Cohen, Noah A.Sharma, ShuchitaUribarri, Jaime2020-06-16T07:39:41-07:00doi:10.1681/ASN.2020050599hwp:resource-id:jnephrol;31/8/1680American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologydialysis, peritoneal dialysis, acute renal failure, COVID-19Research LetterResearch 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