en-usCOVID-19: In ContextCOVID-19 is particularly threatening to patients with kidney disease and to their caregivers. JASN, CJASN, and Kidney360 are sharing valid, peer reviewed information as quickly as possible. This collection of COVID-19 articles is updated with new contextual articles such as <b>Global and Patient Perspectives, Feature Articles, Reviews and Editorials</b>. Articles are added to the collection as soon as they are published. <p></p><p></p> <p></p> Original Research articles are available in the <a href="https://cjasn.asnjournals.org/cc/covid-19">COVID-19 Research Collection</a> <p></p> More resources on COVID-19 can be found on the ASN COVID-19 page: <a href="https://www.asn-online.org/covid-19">ASN COVID-19 Resources</a><p></p><p> </p><p> <b> Related Information: </b></p><p></p> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/12/article-p25_16.xml?WT.mc_id=CC">COVID-19 Wellness Module Offered through ASN Website</a> (ASN <i>Kidney News</i>)</li> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/10/11/article-p47_27.xml?WT.mc_id=CC">The ASN COVID-19 Response Team: Finding the Silver Lining</a> (ASN <i>Kidney News)</i>)</li> <li><a href="https://www.kidneynews.org/view/journals/kidney-news/13/9/article-p23_12.xml?WT.mc_id=CC">SARS-CoV-2 Vaccinations in Transplant Recipients: The More the Better </a>(ASN <i>Kidney News</i>)</li> <b>Podcasts: </b> <li><a href="https://www.asn-online.org/media/podcast/CJASN/2021_07_09_CJN17311120.mp3"> CJASN Podcast: Predictive Approaches for Acute Dialysis Requirement and Death in COVID-19</a> </li><li><a href="https://www.asn-online.org/media/podcast/JASN/2021_07_07_JASN2021010104.mp3"> JASN Podcast: Vaccine Acceptability and Hemodialysis Patients </a> </li><li><a href="https://www.asn-online.org/media/podcast/JASN/2021_06_11_JASN2021040536B.mp3"> JASN Podcast: COVID-19 Mortality and the Tough Discussions about Advance Care Planning</a> </li>Tue, 23 Apr 2024 10:33:00 GMThttp://cct.highwire.org/feeds/asn/covid-19-in-context.rssCOVID-19 Vaccination and new onset glomerular disease: Results from the IRocGN2 International registryBackground:Cases of de novo glomerular disease with various renal histologies have been reported after vaccination against SARS-CoV-2. Causality has not been established and the long-term outcomes are not known. To better characterize the glomerular diseases and clinical course/outcomes, we created the International Registry of COVID-19 vaccination and Glomerulonephritis (IRocGN2) to study in aggregate de novo glomerulonephritis cases suspected after COVID-19 vaccine exposure Methods:A RedCap survey was used for anonymized data collection. Detailed information on vaccination type and timing and glomerular disease histology were recorded in the registry. We collected serial information on laboratory values (before and after vaccination and during follow-up), treatments, and kidney-related outcomes. Results: Ninety-eight glomerular disease cases were entered into the registry over eleven months from 44 centers throughout the world. Median follow-up was 89 days after diagnosis. IgA nephropathy (IgAN) and minimal change disease (MCD) were the most the common kidney diseases reported. Recovery of kidney function and remission of proteinuria was more likely in IgAN and MCD at 4-6 months than with pauci immune glomerulonephritis /vasculitis and membranous nephropathy. Conclusions:Development of glomerular disease after vaccination against SARS-CoV-2 may be a very rare adverse event. Temporal association is present for IgAN and MCD, but causality is not firmly established. Kidney outcomes for IgAN and MCD are favorable. No changes in vaccination risk-benefit assessment is recommended based on these findings.waldmanm@niddk.nih.gov10.34067/KID.0006832022Fri, 16 Dec 2022 03:21:56 GMT-08:00COVID-19 Vaccination and new onset glomerular disease: Results from the IRocGN2 International registryBackground:Cases of de novo glomerular disease with various renal histologies have been reported after vaccination against SARS-CoV-2. Causality has not been established and the long-term outcomes are not known. To better characterize the glomerular diseases and clinical course/outcomes, we created the International Registry of COVID-19 vaccination and Glomerulonephritis (IRocGN2) to study in aggregate de novo glomerulonephritis cases suspected after COVID-19 vaccine exposure Methods:A RedCap survey was used for anonymized data collection. Detailed information on vaccination type and timing and glomerular disease histology were recorded in the registry. We collected serial information on laboratory values (before and after vaccination and during follow-up), treatments, and kidney-related outcomes. Results: Ninety-eight glomerular disease cases were entered into the registry over eleven months from 44 centers throughout the world. Median follow-up was 89 days after diagnosis. IgA nephropathy (IgAN) and minimal change disease (MCD) were the most the common kidney diseases reported. Recovery of kidney function and remission of proteinuria was more likely in IgAN and MCD at 4-6 months than with pauci immune glomerulonephritis /vasculitis and membranous nephropathy. Conclusions:Development of glomerular disease after vaccination against SARS-CoV-2 may be a very rare adverse event. Temporal association is present for IgAN and MCD, but causality is not firmly established. Kidney outcomes for IgAN and MCD are favorable. No changes in vaccination risk-benefit assessment is recommended based on these findings.Waldman, MerylSinaii, NinetLerma, Edgar V.Kurien, Anila AbrahamJhaveri, Kenar D.Uppal, Nupur N.Wanchoo, RimdaAvasare, RupaliZuckerman, Jonathan E.Liew, AdrianGallan, Alexander J.El-Meanawy, AshrafYagil, YoramLebedev, LarissaBaskaran, KrishobanVilayur, EswariWai Seung, AdrienneWeerasinghe, NethmiPetrakis, IoannisStylianou, KostasGakiopoulou, HarikleiaHamilton, Alexander J.Edney, NaomiMillner, RachelMarinaki, SmaragdiRein, Joshua L.Killen, John PaulRodríguez Chagolla, Jose ManuelBassil, ClaudeLopez del Valle, RamonEvans, JordanUrisman, AnatolyZawaideh, MonaBaxi, Pravir V.Rodby, Roger A.Vankalakunti, MaheshaMejia Vilet, Juan M.Ramirez Andrade, Silvia EuniceHoman, MalVasquez Jimenez, EnzoPerinpanayagam, NatashaVelez, Juan Carlos Q.Mohamed, Muner M.B.Mohammed, Khalid M.GSekar, ArjunOllila, LauraAron, Abraham WArellano Arteaga, Kevin JavierIslam, MahmudBerrio, Esperanza MoralMaoujoud, OmarMorales, Rebecca RufSeipp, ReganSchulze, Carl E.Yenchek, Robert H.Vancea, IrinaMuneeb, MuhammadHoward, LilianCaza, Tiffany N.2022-12-16T15:21:56-08:00doi:10.34067/KID.0006832022hwp:resource-id:kidney360;KID.0006832022v1American Society of NephrologyCopyright © 2022 American Society of NephrologyKidney360covid-19 vaccine, glomerular, kidney, nephrotic, COVID-19, Registries, IRocGN2Original InvestigationOriginal Investigationother202210.34067/KID.00068320222641-76502641-76502022-12-16T15:21:56-08:00Kidney360Original Investigation10.34067/KID.0006832022Lived experiences of hemodialysis healthcare workers during the COVID-19 pandemic: A qualitative study from the Quebec Renal NetworkBackground: The COVID-19 pandemic has disrupted health systems and created numerous challenges in hospitals worldwide for patients and healthcare workers (HCWs). Hemodialysis centers are at risk of COVID-19 outbreaks given the difficulty of maintaining social distancing and the fact that hemodialysis patients are at higher risk of being infected with COVID-19. During the COVID-19 pandemic, HCWs have had to face many challenges and stressors. Our study was designed to gain HCWs' perspectives on their experiences of the impacts of the COVID-19 pandemic in hemodialysis units. Methods: Semi-structured interviews were conducted with 22 HCWs (nurses, nephrologists, pharmacists, social workers, patient attendants, security agents) working in five hemodialysis centers in Montreal, between November 2020 and May 2021. The content of the interviews was analyzed using thematic analysis. Results: Four themes were identified during the interviews. The first was the impact of COVID-19 on work organization, regarding which participants reported an increased workload, a need for a consistent information strategy, and positive innovations such as telemedicine. The second theme was challenges associated with communicating and caring for dialysis patients during the pandemic. The third theme was psychological distress experienced by hemodialysis staff and the psychosocial impact of COVID-19 on their personal lives. The fourth theme was recommendations made by participants for future public health emergencies, such as maintaining public health measures, ensuring an adequate supply of protective equipment and developing a consistent communication strategy. Conclusions: During the first and second waves of the COVID-19 pandemic, HCWs working in hemodialysis units faced multiple challenges that impacted their wellbeing and their work. In order to minimize challenges for HCWs in hemodialysis during a future pandemic, the healthcare system should provide an adequate supply of protective equipment, develop effective communication strategies and take into account the psychological distress related to HCWs' professional and personal lives.marie-chantal.fortin.med@ssss.gouv.qc.ca10.34067/KID.0004252022Tue, 13 Dec 2022 01:29:47 GMT-08:00Lived experiences of hemodialysis healthcare workers during the COVID-19 pandemic: A qualitative study from the Quebec Renal NetworkBackground: The COVID-19 pandemic has disrupted health systems and created numerous challenges in hospitals worldwide for patients and healthcare workers (HCWs). Hemodialysis centers are at risk of COVID-19 outbreaks given the difficulty of maintaining social distancing and the fact that hemodialysis patients are at higher risk of being infected with COVID-19. During the COVID-19 pandemic, HCWs have had to face many challenges and stressors. Our study was designed to gain HCWs' perspectives on their experiences of the impacts of the COVID-19 pandemic in hemodialysis units. Methods: Semi-structured interviews were conducted with 22 HCWs (nurses, nephrologists, pharmacists, social workers, patient attendants, security agents) working in five hemodialysis centers in Montreal, between November 2020 and May 2021. The content of the interviews was analyzed using thematic analysis. Results: Four themes were identified during the interviews. The first was the impact of COVID-19 on work organization, regarding which participants reported an increased workload, a need for a consistent information strategy, and positive innovations such as telemedicine. The second theme was challenges associated with communicating and caring for dialysis patients during the pandemic. The third theme was psychological distress experienced by hemodialysis staff and the psychosocial impact of COVID-19 on their personal lives. The fourth theme was recommendations made by participants for future public health emergencies, such as maintaining public health measures, ensuring an adequate supply of protective equipment and developing a consistent communication strategy. Conclusions: During the first and second waves of the COVID-19 pandemic, HCWs working in hemodialysis units faced multiple challenges that impacted their wellbeing and their work. In order to minimize challenges for HCWs in hemodialysis during a future pandemic, the healthcare system should provide an adequate supply of protective equipment, develop effective communication strategies and take into account the psychological distress related to HCWs' professional and personal lives.Affdal, AliyaMalo, Marie-FrançoiseBlum, DanielBallesteros Gallego, FabianBeaubien-Souligny, WilliamCaron, Marie-LineNadeau-Fredette, Annie-ClaireVasilevsky, MurrayRios, NorkaSuri, Rita S.Fortin, Marie-Chantal2022-12-13T13:29:47-08:00doi:10.34067/KID.0004252022hwp:resource-id:kidney360;KID.0004252022v1American Society of NephrologyCopyright © 2022 American Society of NephrologyKidney360hemodialysis, healthcare providers, COVID-19 pandemic, Qualitative study, Semi-directed interviewsOriginal InvestigationOriginal Investigationother202210.34067/KID.00042520222641-76502641-76502022-12-13T13:29:47-08:00Kidney360Original Investigation10.34067/KID.0004252022A Population-Based Analysis of the Risk of Glomerular Disease Relapse after COVID-19 Vaccination10.1681/ASN.2022030258Fri, 04 Nov 2022 01:16:32 GMT-07:00A Population-Based Analysis of the Risk of Glomerular Disease Relapse after COVID-19 VaccinationCanney, MarkAtiquzzaman, MohammadCunningham, Amanda M.Zheng, YuyanEr, LeeHawken, StevenZhao, YinshanBarbour, Sean J.2022-11-04T13:16:32-07:00doi:10.1681/ASN.2022030258hwp:resource-id:jnephrol;33/12/2247American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical epidemiology, glomerular disease, COVID-19, vaccination, recurrence, glomerulonephritisClinical EpidemiologyGlomerulonephritis and Interstitial NephritisClinical EpidemiologyGlomerulonephritis and Interstitial Nephritisresearch-article20222022-12-01December 202210.1681/ASN.20220302581046-66731533-34502022-11-04T13:16:32-07:002022-12Journal of the American Society of NephrologyClinical Epidemiology3312122247212822572131mRNA COVID-19 Vaccines and Their Risk to Induce a Relapse of Glomerular Diseases10.1681/ASN.2022091078Fri, 04 Nov 2022 01:16:32 GMT-07:00mRNA COVID-19 Vaccines and Their Risk to Induce a Relapse of Glomerular DiseasesKronbichler, AndreasAnders, Hans-Joachim2022-11-04T13:16:32-07:00doi:10.1681/ASN.2022091078hwp:resource-id:jnephrol;33/12/2128American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyglomerular disease, vasculitis, IgA nephropathy, lupus nephritis, focal segmental glomerulosclerosis, membranous nephropathy, COVID-19Up Front MattersEditorialUp Front MattersEditorialeditorial20222022-12-01December 202210.1681/ASN.20220910781046-66731533-34502022-11-04T13:16:32-07:002022-12Journal of the American Society of NephrologyUp Front Matters3312122128224721312257SARS-CoV-2 Infections among Vaccinated Patients on Maintenance Dialysis, January 1–August 31, 2021, United States10.34067/KID.0003092022Tue, 20 Sep 2022 07:33:25 GMT-07:00SARS-CoV-2 Infections among Vaccinated Patients on Maintenance Dialysis, January 1–August 31, 2021, United StatesBardossy, Ana CeciliaAngeles, JeseniaBooth, StephanieFike, LucyWadley, AshleyRha, BrianLacson, EduardoManley, Harold J.Johnson, DougApata, Ibironke W.Novosad, Shannon2022-09-20T07:33:25-07:00doi:10.34067/KID.0003092022hwp:resource-id:kidney360;3/11/1934American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, COVID-19, COVID-19 vaccine, end stage renal disease, ESKD, SARS-CoV-2, United StatesBrief CommunicationDialysisBrief CommunicationDialysisresearch-article20222022-11-2410.34067/KID.00030920222641-76502022-09-20T07:33:25-07:002022-11-24Kidney360Brief Communication31119341938Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to Severity10.1681/ASN.2022010125Tue, 30 Aug 2022 07:22:48 GMT-07:00Blood Transcriptomes of SARS-CoV-2–Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to SeveritySun, ZeguoZhang, ZhongyangBanu, KhadijaAzzi, Yorg AlReghuvaran, AnandFredericks, SamuelPlanoutene, MarinaHartzell, SusanKim, YeslPell, JohnTietjen, GregoryAsch, WilliamKulkarni, SanjayFormica, RichardRana, MeenakshiMaltzman, Jonathan S.Zhang, WeijiaAkalin, EnverHeeger, Peter S.Cravedi, PaoloMenon, Madhav C.2022-08-30T07:22:48-07:00doi:10.1681/ASN.2022010125hwp:resource-id:jnephrol;33/11/2108American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, COVID-19, immune deficiency, SARS-CoV-2, transcriptomeClinical ResearchTransplantationClinical ResearchTransplantationresearch-article20222022-11-01November 202210.1681/ASN.20220101251046-66731533-34502022-08-30T07:22:48-07:002022-11Journal of the American Society of NephrologyClinical Research331121082122Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients10.34067/KID.0002542022Wed, 10 Aug 2022 01:41:42 GMT-07:00Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis PatientsValentini, NicolasMarchitto, LorieRaymond, MaximeGoyette, GuillaumeKaufmann, Daniel E.Finzi, AndrésSuri, Rita S.Lamarche, Caroline2022-08-10T13:41:42-07:00doi:10.34067/KID.0002542022hwp:resource-id:kidney360;3/10/1763American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360chronic kidney disease, basic science, COVID-19, dendritic cell, immune response, innate immunity, monocyte, mRNA vaccine, SARS-CoV-2Brief CommunicationChronic Kidney DiseaseBrief CommunicationChronic Kidney Diseaserapid-communication20222022-10-2710.34067/KID.00025420222641-76502022-08-10T13:41:42-07:002022-10-27Kidney360Brief Communication31017631768International Practices on COVID-19 Vaccine Mandates for Transplant Candidates10.34067/KID.0004062022Mon, 15 Aug 2022 01:52:02 GMT-07:00International Practices on COVID-19 Vaccine Mandates for Transplant CandidatesCaliskan, YasarHippen, Benjamin E.Axelrod, David A.Schnitzler, MarkMaher, KennanAlhamad, TarekLam, Ngan N.Anwar, SiddiqKute, VivekLentine, Krista L.2022-08-15T13:52:02-07:00doi:10.34067/KID.0004062022hwp:resource-id:kidney360;3/10/1754American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, COVID-19, international practices, patient safety, solid organ transplantation, vaccines, waitlist managementOriginal InvestigationTransplantationOriginal InvestigationTransplantationresearch-article20222022-10-2710.34067/KID.00040620222641-76502022-08-15T13:52:02-07:002022-10-27Kidney360Original Investigation31017541762Global Perspectives in Acute Kidney Injury: England10.34067/KID.0000052022Wed, 29 Jun 2022 04:04:15 GMT-07:00Global Perspectives in Acute Kidney Injury: EnglandLewington, AndrewBonfield, Becky2022-06-29T04:04:15-07:00doi:10.34067/KID.0000052022hwp:resource-id:kidney360;3/8/1435American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, acute kidney injury, AKI alerts, COVID-19, England, epidemiology, guidelines, outcomesGlobal PerspectiveGlobal Perspectiveresearch-article20222022-08-2510.34067/KID.00000520222641-76502022-06-29T04:04:15-07:002022-08-25Kidney360Global Perspective3814351438Prescribing Nirmatrelvir/Ritonavir for COVID-19 in Advanced CKD10.2215/CJN.05270522Thu, 09 Jun 2022 09:42:01 GMT-07:00Prescribing Nirmatrelvir/Ritonavir for COVID-19 in Advanced CKDHiremath, SwapnilMcGuinty, MichaelineArgyropoulos, ChristosBrimble, K. ScottBrown, Pierre AntoineChagla, ZainCooper, RebeccaHoar, StephanieJuurlink, DavidTreleaven, DarinWalsh, MichaelYeung, AngieBlake, Peter2022-06-09T09:42:01-07:00doi:10.2215/CJN.05270522hwp:resource-id:clinjasn;17/8/1247American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysis, drug metabolism, pharmacokinetics, transplantation, chronic kidney diseasePerspectivePerspectiveresearch-article20222022-08-01August 202210.2215/CJN.052705221555-90411555-905X2022-06-09T09:42:01-07:002022-08Clinical Journal of the American Society of NephrologyPerspective17812471250Collaboration between Dialysis Providers10.1681/ASN.2021111475Thu, 02 Jun 2022 10:56:36 GMT-07:00Collaboration between Dialysis ProvidersSilberzweig, JeffreyBhat, J. GaneshDittrich, Mary O.Durvasula, RaghuGiullian, JeffHymes, Jeffrey L.Johnson, DougSchiller, BrigitteSpech, RichardSpry, LeslieWalker, Geoffrey ScottWatnick, SuzanneYee, JerryFreedman, Barry I.2022-06-02T10:56:36-07:00doi:10.1681/ASN.2021111475hwp:resource-id:jnephrol;33/8/1440American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, dialysis, end stage kidney disease, outcomes, patient-centered careUp Front MattersPerspectiveUp Front MattersPerspectiveresearch-article20222022-08-01August 202210.1681/ASN.20211114751046-66731533-34502022-06-02T10:56:36-07:002022-08Journal of the American Society of NephrologyUp Front Matters33814401444Vaccination, Transplantation, and a Social Contract10.1681/ASN.2021111501Wed, 11 May 2022 08:24:36 GMT-07:00Vaccination, Transplantation, and a Social ContractKates, Olivia S.Limaye, Ajit P.Kaplan, Bruce2022-05-11T08:24:36-07:00doi:10.1681/ASN.2021111501hwp:resource-id:jnephrol;33/8/1445American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyvirology, transplantation, kidney transplantation, COVID-19, SARS-CoV-2, COVID-19 vaccinesUp Front MattersPerspectiveUp Front MattersPerspectiveresearch-article20222022-08-01August 202210.1681/ASN.20211115011046-66731533-34502022-05-11T08:24:36-07:002022-08Journal of the American Society of NephrologyUp Front Matters33814451447Lifesaving Care for Patients with Kidney Failure during the War in Ukraine 202210.2215/CJN.04720422Tue, 10 May 2022 06:43:13 GMT-07:00Lifesaving Care for Patients with Kidney Failure during the War in Ukraine 2022Stepanova, NataliaKolesnyk, MykolaMithani, ZainAlkofair, BaneenShakour, Rebecca LaurenPetrova, AnnaNovakivskyy, VolodymyrHymes, Jeffrey L.Brzosko, SzymonGiullian, JeffEspinel, ZeldeShultz, James M.2022-05-10T06:43:13-07:00doi:10.2215/CJN.04720422hwp:resource-id:clinjasn;17/7/1079American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney disease, hemodialysis, equity, epidemiology and outcomes, end stage kidney disease, end-stage renal disease, disparity, dialysis, COVID-19, UkrainePerspectivePerspectiveresearch-article20222022-07-01July 202210.2215/CJN.047204221555-90411555-905X2022-05-10T06:43:13-07:002022-07Clinical Journal of the American Society of NephrologyPerspective17710791081Authors’ Reply: Clinical Studies of Vaccine Efficacy10.1681/ASN.2022030382Tue, 21 Jun 2022 07:17:29 GMT-07:00Authors’ Reply: Clinical Studies of Vaccine EfficacyBell, SamiraCampbell, JacquelineLambourg, EmilieMark, Patrick2022-06-21T07:17:29-07:00doi:10.1681/ASN.2022030382hwp:resource-id:jnephrol;33/7/1430American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyvaccination, COVID-19, clinical epidemiology, dialysis, transplantation, kidney replacement therapyLetter to the EditorLetter to the Editorletter20222022-07-01July 202210.1681/ASN.20220303821046-66731533-34502022-06-21T07:17:29-07:002022-07Journal of the American Society of NephrologyLetter to the Editor337741430142867714311430686Clinical Studies of Vaccine Efficacy10.1681/ASN.2022030300Tue, 21 Jun 2022 07:17:30 GMT-07:00Clinical Studies of Vaccine EfficacyAshby, Damien2022-06-21T07:17:30-07:00doi:10.1681/ASN.2022030300hwp:resource-id:jnephrol;33/7/1428American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologycovid-19, VaccinationLetter to the EditorLetter to the Editorletter20222022-07-01July 202210.1681/ASN.20220303001046-66731533-34502022-06-21T07:17:30-07:002022-07Journal of the American Society of NephrologyLetter to the Editor337741428143067714301431686Exacerbation of Racial Disparities in Living Donor Kidney Transplantation During the COVID-19 Pandemic10.34067/KID.0008392021Thu, 05 May 2022 01:22:35 GMT-07:00Exacerbation of Racial Disparities in Living Donor Kidney Transplantation During the COVID-19 PandemicSingh, NeerajLi, RuixinAlhamad, TarekSchnitzler, Mark A.Mannon, Roslyn B.Doshi, Mona D.Woodside, Kenneth J.Hippen, Benjamin E.Cooper, MatthewSnyder, JonAxelrod, David A.Lentine, Krista L.2022-05-05T13:22:35-07:00doi:10.34067/KID.0008392021hwp:resource-id:kidney360;3/6/1089American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, access, COVID-19, disparities, kidney transplantation, living donor transplantation, SARS-CoV-2Brief CommunicationTransplantationBrief CommunicationTransplantationresearch-article20222022-06-3010.34067/KID.00083920212641-76502022-05-05T13:22:35-07:002022-06-30Kidney360Brief Communication3610891094The Impact of COVID-19 on Postdischarge Outcomes for Dialysis Patients in the United States: Evidence from Medicare Claims Data10.34067/KID.0000242022Fri, 15 Apr 2022 01:32:21 GMT-07:00The Impact of COVID-19 on Postdischarge Outcomes for Dialysis Patients in the United States: Evidence from Medicare Claims DataWu, WenboGremel, Garrett W.He, KevinMessana, Joseph M.Sen, AnandaSegal, Jonathan H.Dahlerus, ClaudiaHirth, Richard A.Kang, JianWisniewski, KarenNahra, TammiePadilla, RobinTong, LanGu, HaoyuWang, XiSlowey, MeganEckard, AshleyDing, XuemeiBorowicz, LisaDu, JuanFrye, BrandonKalbfleisch, John D.2022-04-15T13:32:21-07:00doi:10.34067/KID.0000242022hwp:resource-id:kidney360;3/6/1047American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, aftercare, COVID-19, patient discharge, SARS-CoV-2, United StatesOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-06-3010.34067/KID.00002420222641-76502022-04-15T13:32:21-07:002022-06-30Kidney360Original Investigation3610471056COVID-19 Vaccination for Patients Undergoing Long-Term Hemodialysis10.2215/CJN.04460422Wed, 01 Jun 2022 11:44:27 GMT-07:00COVID-19 Vaccination for Patients Undergoing Long-Term HemodialysisKorst, Uwe K.H.2022-06-01T11:44:27-07:00doi:10.2215/CJN.04460422hwp:resource-id:clinjasn;17/6/767American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, vaccination, hemodialysisPatient VoicePatient Voiceresearch-article20222022-06-01June 202210.2215/CJN.044604221555-90411555-905X2022-06-01T11:44:27-07:002022-06Clinical Journal of the American Society of NephrologyPatient Voice17666767843779768850781Clinical Utility of COVID-19 Vaccination in Patients Undergoing Hemodialysis10.2215/CJN.04930422Wed, 01 Jun 2022 11:44:27 GMT-07:00Clinical Utility of COVID-19 Vaccination in Patients Undergoing HemodialysisOliver, Matthew J.Blake, Peter G.2022-06-01T11:44:27-07:00doi:10.2215/CJN.04930422hwp:resource-id:clinjasn;17/6/779American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, chronic hemodialysis, vaccinationEditorialEditorialeditorial20222022-06-01June 202210.2215/CJN.049304221555-90411555-905X2022-06-01T11:44:27-07:002022-06Clinical Journal of the American Society of NephrologyEditorial17666779843767781850768Learnings from Throwing Paint at the Wall for COVID-19 with an SGLT2 Inhibitor10.2215/CJN.03250322Thu, 28 Apr 2022 05:35:08 GMT-07:00Learnings from Throwing Paint at the Wall for COVID-19 with an SGLT2 InhibitorTuttle, Katherine R.2022-04-28T05:35:08-07:00doi:10.2215/CJN.03250322hwp:resource-id:clinjasn;17/5/628American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologySARS-CoV-2, acute kidney injury, pandemic, dapagliflozin, GFR, safety, COVID-19, sodium-glucose cotransporter 2, SGLT2EditorialEditorialeditorial20222022-05-01May 202210.2215/CJN.032503221555-90411555-905X2022-04-28T05:35:08-07:002022-05Clinical Journal of the American Society of NephrologyEditorial1755628643630654SARS-CoV-2 Vaccine Mandates for Patients on the Kidney Transplant Waitlist10.2215/CJN.15611121Wed, 02 Mar 2022 09:43:50 GMT-08:00SARS-CoV-2 Vaccine Mandates for Patients on the Kidney Transplant WaitlistTallaa, FaissalGunaratnam, LakshmanSuri, Rita S.2022-03-02T09:43:50-08:00doi:10.2215/CJN.15611121hwp:resource-id:clinjasn;17/5/746American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologytransplantation, vaccination, ethics, dialysis, COVID-19PerspectivePerspectiveresearch-article20222022-05-01May 202210.2215/CJN.156111211555-90411555-905X2022-03-02T09:43:50-08:002022-05Clinical Journal of the American Society of NephrologyPerspective175746748The Impact of Vaccination on Incidence and Outcomes of SARS-CoV-2 Infection in Patients with Kidney Failure in Scotland10.1681/ASN.2022010046Wed, 02 Feb 2022 09:35:54 GMT-08:00The Impact of Vaccination on Incidence and Outcomes of SARS-CoV-2 Infection in Patients with Kidney Failure in ScotlandBell, SamiraCampbell, JacquelineLambourg, EmilieWatters, ChrissieO’Neil, MartinAlmond, AlisonBuck, KatharineCarr, Edward J.Clark, LauraCousland, ZoeFindlay, MarkJoss, NicolaMetcalfe, WendyPetrie, MichaelaSpalding, ElaineTraynor, Jamie P.Sanu, VinodThomson, PeterMethven, ShonaMark, Patrick B.2022-02-02T09:35:54-08:00doi:10.1681/ASN.2022010046hwp:resource-id:jnephrol;33/4/677American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical epidemiology, vaccination, COVID-19, dialysis, transplantation, kidney replacement therapyRapid CommunicationsRapid Communicationsresearch-article20222022-04-01April 202210.1681/ASN.20220100461046-66731533-34502022-02-02T09:35:54-08:002022-04Journal of the American Society of NephrologyRapid Communications33334677677122814281430686122814301431Authors’ Reply: SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?10.1681/ASN.2022010033Mon, 14 Feb 2022 09:17:25 GMT-08:00Authors’ Reply: SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?Schrezenmeier, EvaSattler, ArneHalleck, FabianBudde, Klemens2022-02-14T09:17:25-08:00doi:10.1681/ASN.2022010033hwp:resource-id:jnephrol;33/4/870American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, vaccination, transplantationLetter to the EditorLetter to the Editorletter20222022-04-01April 202210.1681/ASN.20220100331046-66731533-34502022-02-14T09:17:25-08:002022-04Journal of the American Society of NephrologyLetter to the Editor33441287086930278718693033SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?10.1681/ASN.2021121566Mon, 14 Feb 2022 10:29:21 GMT-08:00SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Should We Consider Intradermal Vaccination?Wijtvliet, VeerleWissing, Karl MartinAbramowicz, DanielLedeganck, Kristien J.2022-02-14T10:29:21-08:00doi:10.1681/ASN.2021121566hwp:resource-id:jnephrol;33/4/869American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyintradermal vaccination, kidney transplant recipients, SARS-CoV-2, third dose, T lymphocytes, COVID-19 vaccines, COVID-19Letter to the EditorLetter to the Editorletter20222022-04-01April 202210.1681/ASN.20211215661046-66731533-34502022-02-14T10:29:21-08:002022-04Journal of the American Society of NephrologyLetter to the Editor33441286987030278708713033Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: PRO10.34067/KID.0006632020Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: PROChung, Kevin K.Olson, Stephen W.2021-08-19T13:30:39-07:00doi:10.34067/KID.0006632020hwp:resource-id:kidney360;3/3/416American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, blood purification, COVID-19, cytokine storm, debates, extracorporeal, pathogen removal, sepsis, viremiaDebates in NephrologyDebates in Nephrologyresearch-article20222022-03-3110.34067/KID.00066320202641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Debates in Nephrology33416418Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: CON10.34067/KID.0007382020Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: CONKashani, KianoushForni, Lui G.2021-08-19T13:30:39-07:00doi:10.34067/KID.0007382020hwp:resource-id:kidney360;3/3/419American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, cytokine storm, debates, extracorporeal purificationDebates in NephrologyDebates in Nephrologyresearch-article20222022-03-3110.34067/KID.00073820202641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Debates in Nephrology33419422Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: COMMENTARY10.34067/KID.0005242021Thu, 19 Aug 2021 01:30:39 GMT-07:00Extracorporeal Blood Purification Is Appropriate in Critically Ill Patients with COVID-19 and Multiorgan Failure: COMMENTARYOstermann, MarliesKoyner, Jay L.2021-08-19T13:30:39-07:00doi:10.34067/KID.0005242021hwp:resource-id:kidney360;3/3/423American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, blood purification, COVID-19, debatesModerator CommentaryModerator Commentaryarticle-commentary20222022-03-3110.34067/KID.00052420212641-76502021-08-19T13:30:39-07:002022-03-31Kidney360Moderator Commentary33423425Growing Understanding of the Clinical and Serologic Effects of COVID-19 Vaccines in Patients Undergoing Long-Term Dialysis10.2215/CJN.00320122Thu, 10 Feb 2022 07:07:48 GMT-08:00Growing Understanding of the Clinical and Serologic Effects of COVID-19 Vaccines in Patients Undergoing Long-Term DialysisHundemer, Gregory L.Sood, Manish M.2022-02-10T07:07:48-08:00doi:10.2215/CJN.00320122hwp:resource-id:clinjasn;17/3/335American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19 dialysis, vaccinesEditorialEditorialeditorial20222022-03-01March 202210.2215/CJN.003201221555-90411555-905X2022-02-10T07:07:48-08:002022-03Clinical Journal of the American Society of NephrologyEditorial17333335395403337402413COVID-19 and Palliative Care10.2215/CJN.01090122Thu, 24 Feb 2022 07:07:11 GMT-08:00COVID-19 and Palliative CareHickey, Edward V.Conway, Paul T.2022-02-24T07:07:11-08:00doi:10.2215/CJN.01090122hwp:resource-id:clinjasn;17/3/333American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, palliative care, patient insights, patient burden, end of life, dialysis, immunocompromised, immunosuppressedPatient VoicePatient Voiceresearch-article20222022-03-01March 202210.2215/CJN.010901221555-90411555-905X2022-02-24T07:07:11-08:002022-03Clinical Journal of the American Society of NephrologyPatient Voice1733333342334349Confirmed Drop in Treatment of Patients with Incident End-Stage Kidney Disease During the Novel Coronavirus Disease 2019 Pandemic10.1681/ASN.2021101296Mon, 31 Jan 2022 10:00:27 GMT-08:00Confirmed Drop in Treatment of Patients with Incident End-Stage Kidney Disease During the Novel Coronavirus Disease 2019 PandemicJacobs, LucasDevresse, ArnaudBaudoux, ThomasCollart, Frédéric2022-01-31T10:00:27-08:00doi:10.1681/ASN.2021101296hwp:resource-id:jnephrol;33/2/455American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyend stage kidney disease, epidemiology and outcomes, hemodialysis, peritoneal dialysis, transplantation, COVID-19, SARS-CoV-2Letter to the EditorLetter to the Editorletter20222022-02-01February 202210.1681/ASN.20211012961046-66731533-34502022-01-31T10:00:27-08:002022-02Journal of the American Society of NephrologyLetter to the Editor33221145545529484554572957Secondary Immunodeficiency Related to Kidney Disease (SIDKD)—Definition, Unmet Need, and MechanismsKidney disease is a known risk factor for poor outcomes of COVID-19 and many other serious infections. Conversely, infection is the second most common cause of death in patients with kidney disease. However, little is known about the underlying secondary immunodeficiency related to kidney disease (SIDKD). In contrast to cardiovascular disease related to kidney disease, which has triggered countless epidemiologic, clinical, and experimental research activities or interventional trials, investments in tracing, understanding, and therapeutically targeting SIDKD have been sparse. As a call for more awareness of SIDKD as an imminent unmet medical need that requires rigorous research activities at all levels, we review the epidemiology of SIDKD and the numerous aspects of the abnormal immunophenotype of patients with kidney disease. We propose a definition of SIDKD and discuss the pathogenic mechanisms of SIDKD known thus far, including more recent insights into the unexpected immunoregulatory roles of elevated levels of FGF23 and hyperuricemia and shifts in the secretome of the intestinal microbiota in kidney disease. As an ultimate goal, we should aim to develop therapeutics that can reduce mortality due to infections in patients with kidney disease by normalizing host defense to pathogens and immune responses to vaccines.10.1681/ASN.2021091257Tue, 14 Dec 2021 07:50:01 GMT-08:00Secondary Immunodeficiency Related to Kidney Disease (SIDKD)—Definition, Unmet Need, and MechanismsKidney disease is a known risk factor for poor outcomes of COVID-19 and many other serious infections. Conversely, infection is the second most common cause of death in patients with kidney disease. However, little is known about the underlying secondary immunodeficiency related to kidney disease (SIDKD). In contrast to cardiovascular disease related to kidney disease, which has triggered countless epidemiologic, clinical, and experimental research activities or interventional trials, investments in tracing, understanding, and therapeutically targeting SIDKD have been sparse. As a call for more awareness of SIDKD as an imminent unmet medical need that requires rigorous research activities at all levels, we review the epidemiology of SIDKD and the numerous aspects of the abnormal immunophenotype of patients with kidney disease. We propose a definition of SIDKD and discuss the pathogenic mechanisms of SIDKD known thus far, including more recent insights into the unexpected immunoregulatory roles of elevated levels of FGF23 and hyperuricemia and shifts in the secretome of the intestinal microbiota in kidney disease. As an ultimate goal, we should aim to develop therapeutics that can reduce mortality due to infections in patients with kidney disease by normalizing host defense to pathogens and immune responses to vaccines.Steiger, StefanieRossaint, JanZarbock, AlexanderAnders, Hans-Joachim2021-12-14T07:50:01-08:00doi:10.1681/ASN.2021091257hwp:resource-id:jnephrol;33/2/259American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologykidney disease, immunodeficiency, infection, chronic inflammationReviewReviewreview-article20222022-02-01February 202210.1681/ASN.20210912571046-66731533-34502021-12-14T07:50:01-08:002022-02Journal of the American Society of NephrologyReview332259278The Downside of Telephone Health Visits in a Kidney Transplant Patient during the COVID-19 Pandemic10.34067/KID.0004562021Thu, 27 Jan 2022 08:00:35 GMT-08:00The Downside of Telephone Health Visits in a Kidney Transplant Patient during the COVID-19 PandemicRoss-Smith, Maree S.Wallace, Hannah E.2022-01-27T08:00:35-08:00doi:10.34067/KID.0004562021hwp:resource-id:kidney360;3/1/190American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360clinical nephrology, COVID-19, dialysis, fistula, telehealth, transplantationClinical Images in Nephrology and DialysisClinical Images in Nephrology and Dialysisresearch-article20222022-01-2710.34067/KID.00045620212641-76502022-01-27T08:00:35-08:002022-01-27Kidney360Clinical Images in Nephrology and Dialysis31190191Durable Protection after Anti–SARS-CoV-2 Monoclonal Antibody Therapy10.34067/KID.0007722021Thu, 27 Jan 2022 08:00:34 GMT-08:00Durable Protection after Anti–SARS-CoV-2 Monoclonal Antibody TherapyMisch, Elizabeth A.2022-01-27T08:00:34-08:00doi:10.34067/KID.0007722021hwp:resource-id:kidney360;3/1/8American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360transplantation, COVID-19, kidney transplantation, monoclonal antibody therapy, SARS-CoV-2EditorialEditorialeditorial20222022-01-2710.34067/KID.00077220212641-76502022-01-27T08:00:34-08:002022-01-27Kidney360Editorial31810Protection against SARS-CoV-2 Variants with COVID-19 Vaccination in Kidney Transplant Recipients10.2215/CJN.14881121Wed, 22 Dec 2021 11:26:04 GMT-08:00Protection against SARS-CoV-2 Variants with COVID-19 Vaccination in Kidney Transplant RecipientsBertrand, DominiqueCandon, Sophie2021-12-22T11:26:04-08:00doi:10.2215/CJN.14881121hwp:resource-id:clinjasn;17/1/3American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologySARS-CoV-2, COVID-19, vaccination, kidney transplantationEditorialEditorialeditorial20222022-01-01January 202210.2215/CJN.148811211555-90411555-905X2021-12-22T11:26:04-08:002022-01Clinical Journal of the American Society of NephrologyEditorial17111398151062An Honorable and Ongoing Fight10.2215/CJN.15071121Wed, 22 Dec 2021 11:26:05 GMT-08:00An Honorable and Ongoing FightConway, Paul T.2021-12-22T11:26:05-08:00doi:10.2215/CJN.15071121hwp:resource-id:clinjasn;17/1/1American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney transplantation, nephrology, COVID-19, immunosuppressed, vaccines, vaccination, monoclonal antibodies, Delta variant, Kidney Health InitiativePatient VoicePatient Voiceeditorial20222022-01-01January 202210.2215/CJN.150711211555-90411555-905X2021-12-22T11:26:05-08:002022-01Clinical Journal of the American Society of NephrologyPatient Voice17111198321065Scarce Health Care Resources and Equity during COVID-19: Lessons from the History of Kidney Failure Treatment10.34067/KID.0005292021Sat, 23 Oct 2021 06:07:33 GMT-07:00Scarce Health Care Resources and Equity during COVID-19: Lessons from the History of Kidney Failure TreatmentButler, Catherine R.Wightman, Aaron G.2021-10-23T06:07:33-07:00doi:10.34067/KID.0005292021hwp:resource-id:kidney360;2/12/2024American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, coronavirus disease 2019, COVID-19, delivery of health care, dialysis, ethics, health care resources, policy, renal insufficiency, triagePerspectivePerspectiveresearch-article20212021-12-3010.34067/KID.00052920212641-76502021-10-23T06:07:33-07:002021-12-30Kidney360Perspective21220242026Telehealth and Kidney Disease Care10.2215/CJN.13651021Tue, 07 Dec 2021 11:35:23 GMT-08:00Telehealth and Kidney Disease CareLew, Susie Q.Sikka, Neal2021-12-07T11:35:23-08:00doi:10.2215/CJN.13651021hwp:resource-id:clinjasn;16/12/1784American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologytelehealth, telemedicine, chronic kidney disease, nephrology, internet, COVID-19, end stage kidney disease, virtual visitsEditorialsEditorialseditorial20212021-12-01December 202110.2215/CJN.136510211555-90411555-905X2021-12-07T11:35:23-08:002021-12Clinical Journal of the American Society of NephrologyEditorials16121212178418131773178618231774APOL1 Kidney Risk Variants and Acute Kidney Injury in Those with COVID-1910.2215/CJN.13571021Tue, 07 Dec 2021 11:35:23 GMT-08:00APOL1 Kidney Risk Variants and Acute Kidney Injury in Those with COVID-19Gadegbeku, Crystal A.Sedor, John R.2021-12-07T11:35:23-08:00doi:10.2215/CJN.13571021hwp:resource-id:clinjasn;16/12/1779American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, APOL1, acute kidney injury, social determinants, Black Americans, disparityEditorialsEditorialseditorial20212021-12-01December 202110.2215/CJN.135710211555-90411555-905X2021-12-07T11:35:23-08:002021-12Clinical Journal of the American Society of NephrologyEditorials1612121779179017801796Patient Views on Telehealth for Kidney Disease Care10.2215/CJN.13531021Tue, 07 Dec 2021 11:35:23 GMT-08:00Patient Views on Telehealth for Kidney Disease CareGlennon, Julie2021-12-07T11:35:23-08:00doi:10.2215/CJN.13531021hwp:resource-id:clinjasn;16/12/1773American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysis, ESRD, telemedicinePatient VoicePatient Voiceresearch-article20212021-12-01December 202110.2215/CJN.135310211555-90411555-905X2021-12-07T11:35:23-08:002021-12Clinical Journal of the American Society of NephrologyPatient Voice16121212177318131784177418231786COVID-19 Vaccination in Kidney Transplant Recipients: An Ounce Pre-Transplant is Worth a Pound Post-Transplant10.1681/ASN.2021101347Tue, 30 Nov 2021 06:14:42 GMT-08:00COVID-19 Vaccination in Kidney Transplant Recipients: An Ounce Pre-Transplant is Worth a Pound Post-TransplantChandran, SindhuStock, Peter G.2021-11-30T06:14:42-08:00doi:10.1681/ASN.2021101347hwp:resource-id:jnephrol;32/12/2977American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19 vaccination, COVID-19 vaccination booster, immunosuppression, COVID-19Up Front MattersEditorialsUp Front MattersEditorialseditorial20212021-12-01December 202110.1681/ASN.20211013471046-66731533-34502021-11-30T06:14:42-08:002021-12Journal of the American Society of NephrologyUp Front Matters3212122977302729783033Evidence-Based Practices to Reduce COVID-19 Transmission in Dialysis Facilities10.2215/CJN.07220521Wed, 04 Aug 2021 06:10:08 GMT-07:00Evidence-Based Practices to Reduce COVID-19 Transmission in Dialysis FacilitiesKliger, Alan S.Garrick, Renee2021-08-04T06:10:08-07:00doi:10.2215/CJN.07220521hwp:resource-id:clinjasn;16/8/1146American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, hemodialysis, evidence-based practiceEditorialsEditorialseditorial20212021-08-01August 202110.2215/CJN.072205211555-90411555-905X2021-08-04T06:10:08-07:002021-08Clinical Journal of the American Society of NephrologyEditorials16888114612371141114812461142Keeping Dialysis Patients Safe10.2215/CJN.08090621Wed, 04 Aug 2021 06:10:08 GMT-07:00Keeping Dialysis Patients SafeWager, Roberta L.2021-08-04T06:10:08-07:00doi:10.2215/CJN.08090621hwp:resource-id:clinjasn;16/8/1141American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysisPatient VoicePatient Voiceresearch-article20212021-08-01August 202110.2215/CJN.080906211555-90411555-905X2021-08-04T06:10:08-07:002021-08Clinical Journal of the American Society of NephrologyPatient Voice16888114112371146114212461148Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic10.2215/CJN.19141220Fri, 12 Mar 2021 06:08:00 GMT-08:00Prioritizing Peritoneal Catheter Placement during the COVID-19 PandemicOliver, Matthew J.Crabtree, John H.2021-03-12T06:08:00-08:00doi:10.2215/CJN.19141220hwp:resource-id:clinjasn;16/8/1281American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyperitoneal dialysis, COVID-19PerspectivesPerspectivesresearch-article20212021-08-01August 202110.2215/CJN.191412201555-90411555-905X2021-03-12T06:08:00-08:002021-08Clinical Journal of the American Society of NephrologyPerspectives16812811283Living Organ Donor Hesitancy about COVID-19 Vaccines: A New Kind of “Source Control Issue”10.34067/KID.0003402021Thu, 29 Jul 2021 05:30:28 GMT-07:00Living Organ Donor Hesitancy about COVID-19 Vaccines: A New Kind of “Source Control Issue”Jorgenson, Margaret R.2021-07-29T05:30:28-07:00doi:10.34067/KID.0003402021hwp:resource-id:kidney360;2/7/1076American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360transplantation, COVID-19, COVID-19 vaccines, living donors, SARS-CoV-2, vaccinesEditorialTransplantationEditorialTransplantationeditorial20212021-07-2910.34067/KID.00034020212641-76502021-07-29T05:30:28-07:002021-07-29Kidney360Editorial2710761077Risks and Benefits of Kidney Transplantation during the COVID-19 Pandemic: Transplant or Not Transplant?COVID-19 has significantly affected the transplant community, by leading to decreased transplant activity and increased waiting list time. As expected, COVID-19 causes substantial mortality in both ESKD and kidney transplant populations. This is due to underlying CKD and a high prevalence of comorbid conditions, such as diabetes mellitus, hypertension, and cardiovascular disease in this group. Transplant programs have faced the difficult decision of weighing the risks and benefits of transplantation during the pandemic. On one hand, there is a risk of COVID-19 exposure leading to infection while patients are on maximum immunosuppression. Alternatively, there are risks of delaying transplantation, which will increase waitlist times and may lead to waitlist-associated morbidity and mortality. Cautious and thoughtful selection of both the recipient’s and donor’s post-transplant management has been required during the pandemic, to mitigate the risk of morbidity and mortality associated with COVID-19. In this review article, we aimed to discuss previous publications related to clinical outcomes of COVID-19 disease in kidney transplant recipients, patients with ESKD on dialysis, or on the transplant waiting list, and the precautions transplant centers should take in decision making for recipient and donor selection and immunosuppressive management during the pandemic. Nevertheless, transplantation in this milieu does seem to be the correct decision, with careful patient and donor selection and safeguard protocols for infection prevention. Each center should conduct risk assessment on the basis of the patient’s age and medical comorbidities, waitlist time, degree of sensitization, cold ischemia time, status of vaccination, and severity of pandemic in their region.10.34067/KID.0002532021Thu, 13 May 2021 05:57:09 GMT-07:00Risks and Benefits of Kidney Transplantation during the COVID-19 Pandemic: Transplant or Not Transplant?COVID-19 has significantly affected the transplant community, by leading to decreased transplant activity and increased waiting list time. As expected, COVID-19 causes substantial mortality in both ESKD and kidney transplant populations. This is due to underlying CKD and a high prevalence of comorbid conditions, such as diabetes mellitus, hypertension, and cardiovascular disease in this group. Transplant programs have faced the difficult decision of weighing the risks and benefits of transplantation during the pandemic. On one hand, there is a risk of COVID-19 exposure leading to infection while patients are on maximum immunosuppression. Alternatively, there are risks of delaying transplantation, which will increase waitlist times and may lead to waitlist-associated morbidity and mortality. Cautious and thoughtful selection of both the recipient’s and donor’s post-transplant management has been required during the pandemic, to mitigate the risk of morbidity and mortality associated with COVID-19. In this review article, we aimed to discuss previous publications related to clinical outcomes of COVID-19 disease in kidney transplant recipients, patients with ESKD on dialysis, or on the transplant waiting list, and the precautions transplant centers should take in decision making for recipient and donor selection and immunosuppressive management during the pandemic. Nevertheless, transplantation in this milieu does seem to be the correct decision, with careful patient and donor selection and safeguard protocols for infection prevention. Each center should conduct risk assessment on the basis of the patient’s age and medical comorbidities, waitlist time, degree of sensitization, cold ischemia time, status of vaccination, and severity of pandemic in their region.Ajaimy, MariaLiriano-Ward, LuzGraham, Jay A.Akalin, Enver2021-05-13T05:57:09-07:00doi:10.34067/KID.0002532021hwp:resource-id:kidney360;2/7/1179American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360transplantation, chronic kidney failure, COVID-19, kidney transplantation, pandemics, risk assessment, SARS-CoV-2, transplantsReview ArticleReview Articleresearch-article20212021-07-2910.34067/KID.00025320212641-76502021-05-13T05:57:09-07:002021-07-29Kidney360Review Article2711791187Shining More Light on RAS Inhibition during the COVID-19 Pandemic10.2215/CJN.06000521Mon, 12 Jul 2021 07:54:45 GMT-07:00Shining More Light on RAS Inhibition during the COVID-19 PandemicRianto, FitraSparks, Matthew A.2021-07-12T07:54:45-07:00doi:10.2215/CJN.06000521hwp:resource-id:clinjasn;16/7/1002American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, ACE inhibitors, angiotensin, kidney transplantation, dialysis, mortality, virologyEditorialEditorialeditorial20212021-07-01July 202110.2215/CJN.060005211555-90411555-905X2021-07-12T07:54:45-07:002021-07Clinical Journal of the American Society of NephrologyEditorial16777100210611005100410721014Balancing the Needs of Acute and Maintenance Dialysis Patients during the COVID-19 PandemicThe COVID-19 pandemic continues to strain health care systems and drive shortages in medical supplies and equipment around the world. Resource allocation in times of scarcity requires transparent, ethical frameworks to optimize decision making and reduce health care worker and patient distress. The complexity of allocating dialysis resources for both patients receiving acute and maintenance dialysis has not previously been addressed. Using a rapid, collaborative, and iterative process, BC Renal, a provincial network in Canada, engaged patients, doctors, ethicists, administrators, and nurses to develop a framework for addressing system capacity, communication challenges, and allocation decisions. The guiding ethical principles that underpin this framework are (1) maximizing benefits, (2) treating people fairly, (3) prioritizing the worst-off individuals, and (4) procedural justice. Algorithms to support resource allocation and triage of patients were tested using simulations, and the final framework was reviewed and endorsed by members of the provincial nephrology community. The unique aspects of this allocation framework are the consideration of two diverse patient groups who require dialysis (acute and maintenance), and the application of two allocation criteria (urgency and prognosis) to each group in a sequential matrix. We acknowledge the context of the Canadian health care system, and a universal payer in which this framework was developed. The intention is to promote fair decision making and to maintain an equitable reallocation of limited resources for a complex problem during a pandemic.10.2215/CJN.07460520Mon, 08 Feb 2021 09:47:52 GMT-08:00Balancing the Needs of Acute and Maintenance Dialysis Patients during the COVID-19 PandemicThe COVID-19 pandemic continues to strain health care systems and drive shortages in medical supplies and equipment around the world. Resource allocation in times of scarcity requires transparent, ethical frameworks to optimize decision making and reduce health care worker and patient distress. The complexity of allocating dialysis resources for both patients receiving acute and maintenance dialysis has not previously been addressed. Using a rapid, collaborative, and iterative process, BC Renal, a provincial network in Canada, engaged patients, doctors, ethicists, administrators, and nurses to develop a framework for addressing system capacity, communication challenges, and allocation decisions. The guiding ethical principles that underpin this framework are (1) maximizing benefits, (2) treating people fairly, (3) prioritizing the worst-off individuals, and (4) procedural justice. Algorithms to support resource allocation and triage of patients were tested using simulations, and the final framework was reviewed and endorsed by members of the provincial nephrology community. The unique aspects of this allocation framework are the consideration of two diverse patient groups who require dialysis (acute and maintenance), and the application of two allocation criteria (urgency and prognosis) to each group in a sequential matrix. We acknowledge the context of the Canadian health care system, and a universal payer in which this framework was developed. The intention is to promote fair decision making and to maintain an equitable reallocation of limited resources for a complex problem during a pandemic.Carson, Rachel C.Forzley, BrianThomas, SarahPreto, NinaHargrove, GayleneVirani, AliceAntonsen, JohnBrown, MelanieCopland, MichaelMichaud, MarieSingh, AnuragLevin, Adeera2021-02-08T09:47:52-08:00doi:10.2215/CJN.07460520hwp:resource-id:clinjasn;16/7/1122American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, chronic disease, renal replacement therapy, acute care, ethics, acute kidney injury, triageInvited FeaturesInvited Featuresother20212021-07-01July 202110.2215/CJN.074605201555-90411555-905X2021-02-08T09:47:52-08:002021-07Clinical Journal of the American Society of NephrologyInvited Features16711221130mRNA COVID-19 Vaccine for People with Kidney Failure: Hope but Prudence Warranted10.2215/CJN.04500421Thu, 27 May 2021 09:25:51 GMT-07:00mRNA COVID-19 Vaccine for People with Kidney Failure: Hope but Prudence WarrantedMiskulin, Dana C.Combe, Christian2021-05-27T09:25:51-07:00doi:10.2215/CJN.04500421hwp:resource-id:clinjasn;16/7/996American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysis, seroresponse, vaccinesEditorialEditorialeditorial20212021-07-01July 202110.2215/CJN.045004211555-90411555-905X2021-05-27T09:25:51-07:002021-07Clinical Journal of the American Society of NephrologyEditorial167779961037107399810421082Nephrology—Taking the Lead10.2215/CJN.20061220Mon, 01 Mar 2021 06:01:34 GMT-08:00Nephrology—Taking the LeadAgarwal, Anupam2021-03-01T06:01:34-08:00doi:10.2215/CJN.20061220hwp:resource-id:clinjasn;16/7/1113American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyworkforce, diversity, innovation, COVID-19, nephrologyPerspectivesPerspectivesresearch-article20212021-07-01July 202110.2215/CJN.200612201555-90411555-905X2021-03-01T06:01:34-08:002021-07Clinical Journal of the American Society of NephrologyPerspectives16711131116Vaccine and the Need To Be Heard: Considerations for COVID-19 Immunization in ESKD10.34067/KID.0001932021Thu, 08 Apr 2021 01:50:57 GMT-07:00Vaccine and the Need To Be Heard: Considerations for COVID-19 Immunization in ESKDSrivatana, VeshWilkie, CarolinePerl, JefferyWatnick, Suzanne2021-04-08T13:50:57-07:00doi:10.34067/KID.0001932021hwp:resource-id:kidney360;2/6/1048American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, COVID-19, vaccinePerspectivePerspectiveresearch-article20212021-06-2410.34067/KID.00019320212641-76502021-04-08T13:50:57-07:002021-06-24Kidney360Perspective2610481050High Incidence of Circuit Clotting in Critically Ill COVID-19 Patients Treated with Renal Replacement Therapy10.1681/ASN.2021040528Fri, 28 May 2021 10:31:36 GMT-07:00High Incidence of Circuit Clotting in Critically Ill COVID-19 Patients Treated with Renal Replacement TherapyGrenon, EloïseCanet, Emmanuel2021-05-28T10:31:36-07:00doi:10.1681/ASN.2021040528hwp:resource-id:jnephrol;32/7/1823American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyCOVID-19, renal replacement therapy, circuit clotting, intensive care unit, acute kidney injuryLetters to the EditorLetters to the Editorletter20212021-07-01July 202110.1681/ASN.20210405281046-66731533-34502021-05-28T10:31:36-07:002021-07Journal of the American Society of NephrologyLetters to the Editor327118231611824176Mass Disasters and Burnout in Nephrology PersonnelMass disasters result in extensive health problems and make health care delivery problematic, as has been the case during the COVID-19 pandemic. Although COVID-19 was initially considered a pulmonary problem, it soon became clear that various other organs were involved. Thus, many care providers, including kidney health personnel, were overwhelmed or developed burnout. This review aims to describe the spectrum of burnout in mass disasters and suggests solutions specifically for nephrology personnel by extending previous experience to the COVID-19 pandemic. Burnout (a psychologic response to work-related stress) is already a frequent part of routine nephrology practice and, not surprisingly, is even more common during mass disasters due to increased workload and specific conditions, in addition to individual factors. Avoiding burnout is essential to prevent psychologic and somatic health problems in personnel as well as malpractice, understaffing, and inadequate health care delivery, all of which increase the health care burden of disasters. Burnout may be prevented by predisaster organizational measures, which include developing an overarching plan and optimizing health care infrastructure, and ad hoc disaster-specific measures that encompass both organizational and individual measures. Organizational measures include increasing safety, decreasing workload and fear of malpractice, optimizing medical staffing and material supplies, motivating personnel, providing mental health support, and enabling flexibility in working circumstances. Individual measures include training on coping with stress and problematic conditions, minimizing the stigma of emotional distress, and maintaining physical health. If these measures fall short, asking for external help is mandatory to avoid an inefficient disaster health care response. Minimizing burnout by applying these measures will improve health care provision, thus saving as many lives as possible.10.2215/CJN.08400520Thu, 07 Jan 2021 09:39:06 GMT-08:00Mass Disasters and Burnout in Nephrology PersonnelMass disasters result in extensive health problems and make health care delivery problematic, as has been the case during the COVID-19 pandemic. Although COVID-19 was initially considered a pulmonary problem, it soon became clear that various other organs were involved. Thus, many care providers, including kidney health personnel, were overwhelmed or developed burnout. This review aims to describe the spectrum of burnout in mass disasters and suggests solutions specifically for nephrology personnel by extending previous experience to the COVID-19 pandemic. Burnout (a psychologic response to work-related stress) is already a frequent part of routine nephrology practice and, not surprisingly, is even more common during mass disasters due to increased workload and specific conditions, in addition to individual factors. Avoiding burnout is essential to prevent psychologic and somatic health problems in personnel as well as malpractice, understaffing, and inadequate health care delivery, all of which increase the health care burden of disasters. Burnout may be prevented by predisaster organizational measures, which include developing an overarching plan and optimizing health care infrastructure, and ad hoc disaster-specific measures that encompass both organizational and individual measures. Organizational measures include increasing safety, decreasing workload and fear of malpractice, optimizing medical staffing and material supplies, motivating personnel, providing mental health support, and enabling flexibility in working circumstances. Individual measures include training on coping with stress and problematic conditions, minimizing the stigma of emotional distress, and maintaining physical health. If these measures fall short, asking for external help is mandatory to avoid an inefficient disaster health care response. Minimizing burnout by applying these measures will improve health care provision, thus saving as many lives as possible.Sever, Mehmet SukruOrtiz, AlbertoMaggiore, UmbertoBac-García, EnriqueVanholder, Raymond2021-01-07T09:39:06-08:00doi:10.2215/CJN.08400520hwp:resource-id:clinjasn;16/5/829American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyburnout, massive disaster, earthquake, hurricane, COVID-19, pandemic, nephrologyReviewsReviewsreview-article20212021-05-08May 08, 202110.2215/CJN.084005201555-90411555-905X2021-01-07T09:39:06-08:002021-05-08Clinical Journal of the American Society of NephrologyReviews165829837COVID-19 and Dialysis Patients: Unsolved Problems in Early 202110.1681/ASN.2020121766Fri, 26 Feb 2021 10:17:36 GMT-08:00COVID-19 and Dialysis Patients: Unsolved Problems in Early 2021Kliger, Alan S.Silberzweig, Jeffrey2021-02-26T10:17:36-08:00doi:10.1681/ASN.2020121766hwp:resource-id:jnephrol;32/5/1018American Society of NephrologyCopyright © 2021 by the American Society of Nephrology This is an Open Access article: American Society of NephrologyJournal of the American Society of Nephrologychronic dialysis, COVID-19PerspectivesPerspectivesresearch-article20212021-05-03May 202110.1681/ASN.20201217661046-66731533-34502021-02-26T10:17:36-08:002021-05-03Journal of the American Society of NephrologyPerspectives32510181020SARS-CoV-2 Vaccines in Kidney Transplant Recipients: Will They Be Safe and Effective and How Will We Know?10.1681/ASN.2021010023Wed, 24 Mar 2021 07:54:56 GMT-07:00SARS-CoV-2 Vaccines in Kidney Transplant Recipients: Will They Be Safe and Effective and How Will We Know?Heldman, Madeleine R.Limaye, Ajit P.2021-03-24T07:54:56-07:00doi:10.1681/ASN.2021010023hwp:resource-id:jnephrol;32/5/1021American Society of NephrologyCopyright © 2021 by the American Society of Nephrology This is an Open Access article: American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, virology, organ transplant, COVID-19PerspectivesPerspectivesresearch-article20212021-05-03May 202110.1681/ASN.20210100231046-66731533-34502021-03-24T07:54:56-07:002021-05-03Journal of the American Society of NephrologyPerspectives32510211024COVID-19 and AKI: Where Do We Stand?10.1681/ASN.2020121768Fri, 26 Feb 2021 10:17:36 GMT-08:00COVID-19 and AKI: Where Do We Stand?Palevsky, Paul M.2021-02-26T10:17:36-08:00doi:10.1681/ASN.2020121768hwp:resource-id:jnephrol;32/5/1029American Society of NephrologyCopyright © 2021 by the American Society of Nephrology This is an Open Access article: American Society of NephrologyJournal of the American Society of Nephrologyacute kidney injury, COVID-19, kidney replacement therapy, SARS-CoV-2ReviewsReviewsreview-article20212021-05-03May 202110.1681/ASN.20201217681046-66731533-34502021-02-26T10:17:36-08:002021-05-03Journal of the American Society of NephrologyReviews32510291032Meeting the Demand for Renal Replacement Therapy during the COVID-19 Pandemic: A Manufacturer’s Perspective10.34067/KID.0006192020Tue, 29 Dec 2020 01:46:37 GMT-08:00Meeting the Demand for Renal Replacement Therapy during the COVID-19 Pandemic: A Manufacturer’s PerspectiveAnger, Michael S.Mullon, ClaudyFicociello, Linda H.Thompson, DavidKraus, Michael A.Newcomb, PeteKossmann, Robert J.2020-12-29T13:46:37-08:00doi:10.34067/KID.0006192020hwp:resource-id:kidney360;2/2/350American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, AKI, COVID-19, CRRT, dialysis, dialysis machines, emergency response, manufacturer, manufacturingPerspectivePerspectiveresearch-article20212021-02-2510.34067/KID.00061920202641-76502020-12-29T13:46:37-08:002021-02-25Kidney360Perspective22350354Authors' Reply10.1681/ASN.2020091276Tue, 29 Sep 2020 11:07:03 GMT-07:00Authors' ReplyClarke, Candice L.Prendecki, MariaMcAdoo, Stephen P.Willicombe, Michelle2020-09-29T11:07:03-07:00doi:10.1681/ASN.2020091276hwp:resource-id:jnephrol;31/12/2968-aAmerican Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of NephrologySeroprevalence, COVID-19Letters to the EditorLetters to the Editorletter20202020-12-01December 202010.1681/ASN.20200912761046-66731533-34502020-09-29T11:07:03-07:002020-12Journal of the American Society of NephrologyLetters to the Editor3112122968296729682967Remdesivir in COVID-19 Patients with Impaired Renal Function10.1681/ASN.2020101535Thu, 21 Jan 2021 10:45:06 GMT-08:00Remdesivir in COVID-19 Patients with Impaired Renal FunctionGevers, SannaWelink, Janvan Nieuwkoop, Cees2021-01-21T10:45:06-08:00doi:10.1681/ASN.2020101535hwp:resource-id:jnephrol;32/2/518American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologynephrotoxicity, COVID-19Letters to the EditorLetters to the Editorletter20212021-02-01February 202110.1681/ASN.20201015351046-66731533-34502021-01-21T10:45:06-08:002021-02Journal of the American Society of NephrologyLetters to the Editor3222751851913845195201386Authors’ Reply10.1681/ASN.2020121692Thu, 21 Jan 2021 10:45:07 GMT-08:00Authors’ ReplyAdamsick, Meagan L.Bhattacharyya, Roby P.Sise, Meghan E.,2021-01-21T10:45:07-08:00doi:10.1681/ASN.2020121692hwp:resource-id:jnephrol;32/2/519American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyacute renal failure, COVID-19Letters to the EditorLetters to the Editorletter20212021-02-01February 202110.1681/ASN.20201216921046-66731533-34502021-01-21T10:45:07-08:002021-02Journal of the American Society of NephrologyLetters to the Editor3222751951813845205191386Living behind the Mask amid Two Pandemics: COVID-19 and Social Injustice10.34067/KID.0006422020Tue, 08 Dec 2020 01:29:19 GMT-08:00Living behind the Mask amid Two Pandemics: COVID-19 and Social InjusticeGee, Patrick O.2020-12-08T13:29:19-08:00doi:10.34067/KID.0006422020hwp:resource-id:kidney360;2/1/7American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360chronic kidney disease, COVID-19, pandemics, patient, social injusticePatient PerspectivePatient Perspectiveresearch-article20212021-01-2810.34067/KID.00064220202641-76502020-12-08T13:29:19-08:002021-01-28Kidney360Patient Perspective2179Effect of COVID-19 on Kidney Disease Incidence and ManagementThe COVID-19 outbreak has had substantial effects on the incidence and management of kidney diseases, including AKI, ESKD, GN, and kidney transplantation. Initial reports from China suggested a lower AKI incidence in patients with COVID-19, but more recent studies from North America reveal a much higher incidence, likely due to the higher prevalence of comorbid conditions, such as hypertension, diabetes, and CKD. AKI in this setting is associated with worse outcomes, including the requirement for vasopressors or mechanical ventilation and death. Performing RRT in those with AKI poses challenges, such as limiting exposure of staff, preserving PPE, coagulopathy, and hypoxemia due to acute respiratory distress syndrome. Continuous RRT is the preferred modality, with sustained low-efficiency dialysis also an option, both managed without 1:1 hemodialysis nursing support. Regional citrate is the preferred anticoagulation, but systemic unfractionated heparin may be used in patients with coagulopathy. The ultrafiltration rate has to be set carefully, taking into consideration hypotension, hypoxemia, and responsiveness to presser and ventilatory support. The chance of transmission puts in-center chronic hemodialysis and other immunosuppressed patients at particularly increased risk. Limited data show that patients with CKD are also at increased risk for more severe disease, if infected. Little is known about the virus’s effects on immunocompromised patients with glomerular diseases and kidney transplants, which introduces challenges for management of immunosuppressant regimens. Although there are no standardized guidelines regarding the management of immunosuppression, several groups recommend stopping the antimetabolite in hospitalized transplant patients and continuing a reduced dose of calcineurin inhibitors. This comprehensive review critically appraises the best available evidence regarding the effect of COVID-19 on the incidence and management of kidney diseases. Where evidence is lacking, current expert opinion and clinical guidelines are reviewed, and knowledge gaps worth investigation are identified.10.34067/KID.0006362020Tue, 24 Nov 2020 10:19:10 GMT-08:00Effect of COVID-19 on Kidney Disease Incidence and ManagementThe COVID-19 outbreak has had substantial effects on the incidence and management of kidney diseases, including AKI, ESKD, GN, and kidney transplantation. Initial reports from China suggested a lower AKI incidence in patients with COVID-19, but more recent studies from North America reveal a much higher incidence, likely due to the higher prevalence of comorbid conditions, such as hypertension, diabetes, and CKD. AKI in this setting is associated with worse outcomes, including the requirement for vasopressors or mechanical ventilation and death. Performing RRT in those with AKI poses challenges, such as limiting exposure of staff, preserving PPE, coagulopathy, and hypoxemia due to acute respiratory distress syndrome. Continuous RRT is the preferred modality, with sustained low-efficiency dialysis also an option, both managed without 1:1 hemodialysis nursing support. Regional citrate is the preferred anticoagulation, but systemic unfractionated heparin may be used in patients with coagulopathy. The ultrafiltration rate has to be set carefully, taking into consideration hypotension, hypoxemia, and responsiveness to presser and ventilatory support. The chance of transmission puts in-center chronic hemodialysis and other immunosuppressed patients at particularly increased risk. Limited data show that patients with CKD are also at increased risk for more severe disease, if infected. Little is known about the virus’s effects on immunocompromised patients with glomerular diseases and kidney transplants, which introduces challenges for management of immunosuppressant regimens. Although there are no standardized guidelines regarding the management of immunosuppression, several groups recommend stopping the antimetabolite in hospitalized transplant patients and continuing a reduced dose of calcineurin inhibitors. This comprehensive review critically appraises the best available evidence regarding the effect of COVID-19 on the incidence and management of kidney diseases. Where evidence is lacking, current expert opinion and clinical guidelines are reviewed, and knowledge gaps worth investigation are identified.McAdams, MeredithOstrosky-Frid, MauricioRajora, NilumHedayati, Susan2020-11-24T10:19:10-08:00doi:10.34067/KID.0006362020hwp:resource-id:kidney360;2/1/141American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360acute kidney injury, ICU nephrology, chronic kidney disease, COVID-19, dialysis, end stage kidney diseaseReview ArticlesReview Articlesreview-article20212021-01-2810.34067/KID.00063620202641-76502020-11-24T10:19:10-08:002021-01-28Kidney360Review Articles21141153COVID-19 and APOL1: Understanding Disease Mechanisms through Clinical Observation10.1681/ASN.2020111629Mon, 07 Dec 2020 08:43:40 GMT-08:00COVID-19 and APOL1: Understanding Disease Mechanisms through Clinical ObservationFriedman, David J.2020-12-07T08:43:40-08:00doi:10.1681/ASN.2020111629hwp:resource-id:jnephrol;32/1/1American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of NephrologyAPOL1, collapsing glomerulopathy, transplantation, COVID-19Up Front MattersEditorialsUp Front MattersEditorialseditorial20212021-01-01January 202110.1681/ASN.20201116291046-66731533-34502020-12-07T08:43:40-08:002021-01Journal of the American Society of NephrologyUp Front Matters3211133240Does SARS-CoV-2 Infect the Kidney?10.1681/ASN.2020081229Tue, 13 Oct 2020 06:52:13 GMT-07:00Does SARS-CoV-2 Infect the Kidney?Khan, ShazaChen, LiheYang, Chin-RangRaghuram, ViswanathanKhundmiri, Syed J.Knepper, Mark A.2020-10-13T06:52:13-07:00doi:10.1681/ASN.2020081229hwp:resource-id:jnephrol;31/12/2746American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of NephrologyAKI, COVID-19, proximal tubule, podocyte, ACE2Up Front MattersPerspectivesUp Front MattersPerspectivesresearch-article20202020-12-01December 202010.1681/ASN.20200812291046-66731533-34502020-10-13T06:52:13-07:002020-12Journal of the American Society of NephrologyUp Front Matters311227462748Management of Hemodialysis Patients with Suspected or Confirmed COVID-19 Infection: Perspective from the Spanish Nephrology10.34067/KID.0002602020Fri, 11 Sep 2020 09:31:44 GMT-07:00Management of Hemodialysis Patients with Suspected or Confirmed COVID-19 Infection: Perspective from the Spanish NephrologySánchez-Alvarez, EmilioMacía, Manuelde Sequera Ortiz, Patricia2020-09-11T09:31:44-07:00doi:10.34067/KID.0002602020hwp:resource-id:kidney360;1/11/1254American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, COVID-19, hemodialysis, pandemic, renal dialysis, SpainOriginal InvestigationsDialysisOriginal InvestigationsDialysisresearch-article20202020-11-2510.34067/KID.00026020202641-76502020-09-11T09:31:44-07:002020-11-25Kidney360Original Investigations11112541258Beware the Ides of March: A Fellow’s Perspective on Surviving the COVID-19 Pandemic10.34067/KID.0005442020Thu, 24 Sep 2020 01:29:45 GMT-07:00Beware the Ides of March: A Fellow’s Perspective on Surviving the COVID-19 PandemicHindi, JudyFuca, NicholasSanchez Russo, Luis2020-09-24T13:29:45-07:00doi:10.34067/KID.0005442020hwp:resource-id:kidney360;1/11/1316American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360acute kidney injury and ICU nephrology, COVID-19, pandemics, severe acute respiratory syndrome coronavirus 2PerspectivesPerspectivesresearch-article20202020-11-2510.34067/KID.00054420202641-76502020-09-24T13:29:45-07:002020-11-25Kidney360Perspectives11113161318The Characteristics, Dynamics, and the Risk of Death in COVID-19 Positive Dialysis Patients in London, UK10.34067/KID.0004502020Thu, 10 Sep 2020 08:21:38 GMT-07:00The Characteristics, Dynamics, and the Risk of Death in COVID-19 Positive Dialysis Patients in London, UKKular, DalvirChis Ster, IrinaSarnowski, AlexanderLioudaki, 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of the American Society of NephrologyCOVID-19, Postkidney transplant recipientPatient VoicesPatient Voiceseditorial20202020-09-07September 07, 202010.2215/CJN.087806201555-90411555-905X2020-07-29T08:58:42-07:002020-09-07Clinical Journal of the American Society of NephrologyPatient Voices15912211223Caution in Identifying Coronaviruses by Electron Microscopy10.1681/ASN.2020050755Fri, 10 Jul 2020 10:44:14 GMT-07:00Caution in Identifying Coronaviruses by Electron MicroscopyMiller, Sarah E.Goldsmith, Cynthia S.2020-07-10T10:44:14-07:00doi:10.1681/ASN.2020050755hwp:resource-id:jnephrol;31/9/2223American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of NephrologySARS-CoV-2, electron microscopy, clathrin-coated vesicles, COVID-19, multivesicular bodiesLetters to the EditorLetters to the Editorletter20202020-09-01September 202010.1681/ASN.20200507551046-66731533-34502020-07-10T10:44:14-07:002020-09Journal of the American Society of NephrologyLetters to the Editor31999222322242225222422252226Postmortem Kidney Pathology Findings in Patients with COVID-1910.1681/ASN.2020050744Wed, 29 Jul 2020 09:04:12 GMT-07:00Postmortem Kidney Pathology Findings in Patients with COVID-19Santoriello, DominickKhairallah, PascaleBomback, Andrew S.Xu, KatherineKudose, SatoruBatal, IbrahimBarasch, JonathanRadhakrishnan, JaiD’Agati, VivetteMarkowitz, Glen2020-07-29T09:04:12-07:00doi:10.1681/ASN.2020050744hwp:resource-id:jnephrol;31/9/2158American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologyacute renal failure, pathology, acute tubular injury, COVID-19, SARS-CoV-2, acute kidney injuryClinical ResearchClinical Researchresearch-article20202020-09-01September 202010.1681/ASN.20200507441046-66731533-34502020-07-29T09:04:12-07:002020-09Journal of the American Society of NephrologyClinical Research31921582167Authors’ Reply10.1681/ASN.2020060847Wed, 12 Aug 2020 05:49:14 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by the American Society of NephrologyJournal of the American Society of Nephrologykidney biopsy, histopathology, electron microscopy, COVID-19Letters to the EditorLetters to the Editorletter20202020-09-01September 202010.1681/ASN.20200506301046-66731533-34502020-07-09T07:56:55-07:002020-09Journal of the American Society of NephrologyLetters to the Editor31999222422232225222522242226Rationing Scarce Resources: The Potential Impact of COVID-19 on Patients with Chronic Kidney Disease10.1681/ASN.2020050704Wed, 15 Jul 2020 12:55:08 GMT-07:00Rationing Scarce Resources: The Potential Impact of COVID-19 on Patients with Chronic Kidney DiseaseSilberzweig, JeffreyIkizler, T. 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Nephrologyperitoneal dialysis, COVID-19, home dialysisPerspectivesPerspectivesresearch-article20202020-09-01September 202010.1681/ASN.20200507291046-66731533-34502020-08-03T08:33:52-07:002020-09Journal of the American Society of NephrologyPerspectives31919281930Technology, Telehealth, and Nephrology: The Time Is Now10.34067/KID.0002382020Wed, 03 Jun 2020 10:15:34 GMT-07:00Technology, Telehealth, and Nephrology: The Time Is NowJain, GauravAhmad, MasoodWallace, Eric L.2020-06-03T10:15:34-07:00doi:10.34067/KID.0002382020hwp:resource-id:kidney360;1/8/834American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360clinical nephrology, access to care, apps, COVID-19, health services accessibility, kidney failure, chronic, monitoring, physiologic, pandemics, renal dialysis, renal insufficiency, chronic, telehealth, telemedicine, telenephrology, videoPerspectivePerspectiveresearch-article20202020-08-2710.34067/KID.00023820202641-76502020-06-03T10:15:34-07:002020-08-27Kidney360Perspective18834836Response to COVID-19 Infection in Hemodialysis Patients: An Australian Perspective10.34067/KID.0002492020Fri, 19 Jun 2020 09:12:27 GMT-07:00Response to COVID-19 Infection in Hemodialysis Patients: An Australian PerspectivePolkinghorne, Kevan R.Kerr, Peter G.Boudville, Neil2020-06-19T09:12:27-07:00doi:10.34067/KID.0002492020hwp:resource-id:kidney360;1/8/829American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, acute kidney injury, Australia, COVID-19, dialysis, government, New Zealand, severe acute respiratory syndrome coronavirus 2Global PerspectiveGlobal Perspectiveresearch-article20202020-08-2710.34067/KID.00024920202641-76502020-06-19T09:12:27-07:002020-08-27Kidney360Global Perspective18829833COVID-19 in Patients with Kidney Disease10.2215/CJN.09730620Tue, 07 Jul 2020 07:17:46 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chronic kidney disease, chronic kidney failure, chronic renal failure, COVID-19, dialysis, end stage kidney disease, end-stage renal disease, kidney disease, kidney failurePatient VoicePatient Voiceresearch-article20202020-08-07August 07, 202010.2215/CJN.091006201555-90411555-905X2020-07-02T07:49:00-07:002020-08-07Clinical Journal of the American Society of NephrologyPatient Voice15888107311391087107411451089Possible Protective Effect of Renin-Angiotensin System Inhibitors in COVID-19 Induced Acute Kidney Injury10.1681/ASN.2020050640Wed, 01 Jul 2020 08:29:06 GMT-07:00Possible Protective Effect of Renin-Angiotensin System Inhibitors in COVID-19 Induced Acute Kidney InjuryKow, Chia SiangHasan, Syed Shahzad2020-07-01T08:29:06-07:00doi:10.1681/ASN.2020050640hwp:resource-id:jnephrol;31/8/1917American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologyacute kidney injury, COVID-19, renin-angiotensin system inhibitorLetters to the EditorLetters to the Editorletter20202020-08-01August 202010.1681/ASN.20200506401046-66731533-34502020-07-01T08:29:06-07:002020-08Journal of the American Society of NephrologyLetters to the Editor31881917191819181919COVID-19, Racism, and Racial Disparities in Kidney Disease: Galvanizing the Kidney Community ResponseThis article contains a podcast athttps://www.asn-online.org/media/podcast/JASN/2020_07_21_JASN2020060809.mp310.1681/ASN.2020060809Mon, 13 Jul 2020 11:02:22 GMT-07:00COVID-19, Racism, and Racial Disparities in Kidney Disease: Galvanizing the Kidney Community ResponseThis article contains a podcast athttps://www.asn-online.org/media/podcast/JASN/2020_07_21_JASN2020060809.mp3Crews, Deidra C.Purnell, Tanjala S.2020-07-13T11:02:22-07:00doi:10.1681/ASN.2020060809hwp:resource-id:jnephrol;31/8/1American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of NephrologyEthnic minority, health disparity, COVID-19, chronic 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