en-usAdvancing American Kidney Health (AAKH)In the first major transformation in kidney care in almost 50 years, the Trump Administration in July 2019 announced the the Executive Order on Advancing American Kidney Health . The comprehensive kidney health strategy is designed to bring sweeping changes to care for people with kidney diseases, including reducing the incidence of kidney failure, increase use of home dialysis, greater access to transplantation, and increased support for development of innovative therapies, including artificial kidneys..<p> </p><p> This series of articles, authored by leading kidney care experts from all aspects of the industry - government to policy leaders to treatment providers - have contributed their perspectives. Additionally, ongoing articles are added to the collection as continued advances are made, questions asked, payment models analyzed and more.</p> <p> The nation’s first kidney health strategy aims to reduce the number of Americans with kidney failure by 25% over the next decade. The government also intends to double the number of kidneys available for transplant and provide more options to people with kidney failure, such as a greater emphasis on home dialysis, transplantation, and the creation of an artificial kidney. This special CJASN <a href="https://www.asn-online.org/media/podcast/CJASN/2019_11_05_CJN10180819.mp3"> podcast </a>by former ASN President Mark Rosenberg and ASN Executive Vice President Tod Ibrahim discuss winning the war on kidney disease.</p>Thu, 18 Apr 2024 09:11:15 GMThttp://cct.highwire.org/feeds/asn/AAKHI.rssReducing the Risks of Home Dialysis Innovation and Uptake10.2215/CJN.05100422Fri, 12 Aug 2022 11:11:52 GMT-07:00Reducing the Risks of Home Dialysis Innovation and UptakeCahill, ZacharyConway, Paul T.Lim, Mark D.2022-08-12T11:11:52-07:00doi:10.2215/CJN.05100422hwp:resource-id:clinjasn;17/11/1688American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyhemodialysisPerspectivePerspectiveresearch-article20222022-11-01November 202210.2215/CJN.051004221555-90411555-905X2022-08-12T11:11:52-07:002022-11Clinical Journal of the American Society of NephrologyPerspective171116881690A Comparison of US Medicare Expenditures for Hemodialysis and Peritoneal Dialysis10.1681/ASN.2022020221Thu, 18 Aug 2022 07:51:16 GMT-07:00A Comparison of US Medicare Expenditures for Hemodialysis and Peritoneal DialysisKaplan, Jennifer M.Niu, JingboHo, VivianWinkelmayer, Wolfgang C.Erickson, Kevin F.2022-08-18T07:51:16-07:00doi:10.1681/ASN.2022020221hwp:resource-id:jnephrol;33/11/2059American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical epidemiology, dialysis, economic analysis, peritoneal dialysis, United States, health expenditures, MedicareClinical EpidemiologyDialysisClinical EpidemiologyDialysisresearch-article20222022-11-01November 202210.1681/ASN.20220202211046-66731533-34502022-08-18T07:51:16-07:002022-11Journal of the American Society of NephrologyClinical Epidemiology331111112059i19632070i1965Basic Requirements for Improving Home Dialysis Utilization: Specialty Nephrology Care and Pre-End Stage Kidney Disease Educationashutosh.shukla@medicine.ufl.edu10.1681/ASN.2022060685Tue, 25 Oct 2022 10:46:47 GMT-07:00Basic Requirements for Improving Home Dialysis Utilization: Specialty Nephrology Care and Pre-End Stage Kidney Disease EducationShukla, AshutoshCavanaugh, KerriWadhwa, AnuradhaCrowley, SusanFried, Linda2022-10-25T10:46:47-07:00doi:10.1681/ASN.2022060685hwp:resource-id:jnephrol;ASN.2022060685v1American Society of NephrologyJournal of the American Society of NephrologyInvited FeatureInvited Featureresearch-article202210.1681/ASN.20220606851046-66731533-34502022-10-25T10:46:47-07:00Journal of the American Society of NephrologyInvited FeatureASN.2022060685Survey of Salary and Job Satisfaction of Transplant Nephrologists in the United States10.2215/CJN.03490322Mon, 01 Aug 2022 06:15:52 GMT-07:00Survey of Salary and Job Satisfaction of Transplant Nephrologists in the United StatesSingh, NeerajDoshi, Mona D.Schold, Jesse D.Preczewski, LukeKlein, ChristinaAkalin, EnverLeca, NicolaeNicoll, KimberlyPesavento, ToddDadhania, Darshana M.Friedewald, JohnSamaniego-Picota, MilagrosBloom, Roy D.Wiseman, Alexander C.2022-08-01T06:15:52-07:00doi:10.2215/CJN.03490322hwp:resource-id:clinjasn;17/9/1372American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologycardiovascular disease, chronic kidney disease, epidemiology and outcomes, lipidsOriginal ArticleTransplantationOriginal ArticleTransplantationresearch-article20222022-09-01September 202210.2215/CJN.034903221555-90411555-905X2022-08-01T06:15:52-07:002022-09Clinical Journal of the American Society of NephrologyOriginal Article17999913721272140314071381127414061409The Advancing American Kidney Health Initiative: The Challenge of Overcoming the Status Quo10.1681/ASN.2022040510Tue, 02 Aug 2022 12:56:00 GMT-07:00The Advancing American Kidney Health Initiative: The Challenge of Overcoming the Status QuoConway, Paul T.Gedney, NieltjeRoy, ShuvoFissell, William H.2022-08-02T12:56:00-07:00doi:10.1681/ASN.2022040510hwp:resource-id:jnephrol;33/9/1797American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologydialysis, kidney transplantation, nephrology, organ transplant, peritoneal dialysis, quality of life, renal dialysis, transplantation, United StatesLetter to the EditorLetter to the Editorletter20222022-09-01September 202210.1681/ASN.20220405101046-66731533-34502022-08-02T12:56:00-07:002022-09Journal of the American Society of NephrologyLetter to the Editor33996179718001060179818011062Authors’ Reply: “The Advancing American Kidney Health Initiative: The Challenge of Overcoming the Status Quo” and “The Advancing American Kidney Health Initiative: Do Not Let 80% Distract Us from the Fact that We Can Do Better”10.1681/ASN.2022050540Tue, 02 Aug 2022 12:56:01 GMT-07:00Authors’ Reply: “The Advancing American Kidney Health Initiative: The Challenge of Overcoming the Status Quo” and “The Advancing American Kidney Health Initiative: Do Not Let 80% Distract Us from the Fact that We Can Do Better”Quinn, Robert R.Lam, Ngan N.Ravani, PietroOliver, Matthew J.Blake, Peter G.Tonelli, Marcello2022-08-02T12:56:01-07:00doi:10.1681/ASN.2022050540hwp:resource-id:jnephrol;33/9/1800American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologychronic kidney failure, end stage kidney disease, dialysis, transplantationLetter to the EditorLetter to the Editorletter20222022-09-01September 202210.1681/ASN.20220505401046-66731533-34502022-08-02T12:56:01-07:002022-09Journal of the American Society of NephrologyLetter to the Editor33999618001797179810601801179817991062Development of a Patient Preference Survey for Wearable Kidney Replacement Therapy Devices10.34067/KID.0001862022Fri, 06 May 2022 11:37:58 GMT-07:00Development of a Patient Preference Survey for Wearable Kidney Replacement Therapy DevicesFlythe, Jennifer E.Forfang, DerekGedney, NieltjeWhite, David M.Wilkie, CarolineCavanaugh, Kerri L.Harris, Raymond C.Unruh, MarkSquillaci, GraceWest, MelissaMansfield, CarolSoloe, Cindy S.Treiman, KatherineWood, DallasHurst, Frank P.Neuland, Carolyn Y.Saha, AninditaSheldon, MurrayTarver, Michelle E.2022-05-06T11:37:58-07:00doi:10.34067/KID.0001862022hwp:resource-id:kidney360;3/7/1197American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, chronic dialysis, clinical trial, dialysis, end stage kidney disease, end stage renal disease, ESRD, hemodialysis, innovation, kidney failure, patient preference, renal replacement therapy, wearable electronic devicesOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-07-2810.34067/KID.00018620222641-76502022-05-06T11:37:58-07:002022-07-28Kidney360Original Investigation3711971209Treatment Decision Making for Older Kidney Patients during COVID-1910.2215/CJN.13241021Tue, 07 Jun 2022 05:24:39 GMT-07:00Treatment Decision Making for Older Kidney Patients during COVID-19Porteny, ThaliaGonzales, Kristina M.Aufort, Kate E.Levine, SarahWong, John B.Isakova, TamaraRifkin, Dena E.Gordon, Elisa J.Rossi, AnaDi Perna, GaryKoch-Weser, SusanWeiner, Daniel E.Ladin, Keren,2022-06-07T05:24:39-07:00doi:10.2215/CJN.13241021hwp:resource-id:clinjasn;17/7/957American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, qualitative research, decision making, SARS-CoV-2, chronic kidney diseaseOriginal ArticleChronic Kidney DiseaseOriginal ArticleChronic Kidney Diseaseresearch-article20222022-07-01July 202210.2215/CJN.132410211555-90411555-905X2022-06-07T05:24:39-07:002022-07Clinical Journal of the American Society of NephrologyOriginal Article177957965Keys to Driving Implementation of the New Kidney Care ModelsContemporary nephrology practice is heavily weighted toward in-center hemodialysis, reflective of decisions on infrastructure and personnel in response to decades of policy. The Advancing American Kidney Health initiative seeks to transform care for patients and providers. Under the initiative’s framework, the Center for Medicare and Medicaid Innovation has launched two new care models that align patient choice with provider incentives. The mandatory ESRD Treatment Choices model requires participation by all nephrology practices in designated Hospital Referral Regions, randomly selecting 30% of all Hospital Referral Regions across the United States for participation, with the remaining Hospital Referral Regions serving as controls. The voluntary Kidney Care Choices model offers alternative payment programs open to nephrology practices throughout the country. To help organize implementation of the models, we developed Driver Diagrams that serve as blueprints to identify structures, processes, and norms and generate intervention concepts. We focused on two goals that are directly applicable to nephrology practices and central to the incentive structure of the ESRD Treatment Choices and Kidney Care Choices: (1) increasing utilization of home dialysis, and (2) increasing the number of kidney transplants. Several recurring themes became apparent with implementation. Multiple stakeholders from assorted backgrounds are needed. Communication with primary care providers will facilitate timely referrals, education, and comanagement. Nephrology providers (nephrologists, nursing, dialysis organizations, others) must lead implementation. Patient engagement at nearly every step will help achieve the aims of the models. Advocacy with federal and state regulatory agencies will be crucial to expanding home dialysis and transplantation access. Although the models hold promise to improve choices and outcomes for many patients, we must be vigilant that they not do reinforce existing disparities in health care or widen known racial, socioeconomic, or geographic gaps. The Advancing American Kidney Health initiative has the potential to usher in a new era of value-based care for nephrology.10.2215/CJN.10880821Mon, 14 Mar 2022 05:54:39 GMT-07:00Keys to Driving Implementation of the New Kidney Care ModelsContemporary nephrology practice is heavily weighted toward in-center hemodialysis, reflective of decisions on infrastructure and personnel in response to decades of policy. The Advancing American Kidney Health initiative seeks to transform care for patients and providers. Under the initiative’s framework, the Center for Medicare and Medicaid Innovation has launched two new care models that align patient choice with provider incentives. The mandatory ESRD Treatment Choices model requires participation by all nephrology practices in designated Hospital Referral Regions, randomly selecting 30% of all Hospital Referral Regions across the United States for participation, with the remaining Hospital Referral Regions serving as controls. The voluntary Kidney Care Choices model offers alternative payment programs open to nephrology practices throughout the country. To help organize implementation of the models, we developed Driver Diagrams that serve as blueprints to identify structures, processes, and norms and generate intervention concepts. We focused on two goals that are directly applicable to nephrology practices and central to the incentive structure of the ESRD Treatment Choices and Kidney Care Choices: (1) increasing utilization of home dialysis, and (2) increasing the number of kidney transplants. Several recurring themes became apparent with implementation. Multiple stakeholders from assorted backgrounds are needed. Communication with primary care providers will facilitate timely referrals, education, and comanagement. Nephrology providers (nephrologists, nursing, dialysis organizations, others) must lead implementation. Patient engagement at nearly every step will help achieve the aims of the models. Advocacy with federal and state regulatory agencies will be crucial to expanding home dialysis and transplantation access. Although the models hold promise to improve choices and outcomes for many patients, we must be vigilant that they not do reinforce existing disparities in health care or widen known racial, socioeconomic, or geographic gaps. The Advancing American Kidney Health initiative has the potential to usher in a new era of value-based care for nephrology.Kshirsagar, Abhijit V.Weiner, Daniel E.Mendu, Mallika L.Liu, FrankLew, Susie Q.O’Neil, Terrence J.Bieber, Scott D.White, David L.Zimmerman, JonathanMohan, Sumit2022-03-14T05:54:39-07:00doi:10.2215/CJN.10880821hwp:resource-id:clinjasn;17/7/1082American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney care models, nephrology, Advancing American Kidney HealthFeatureFeatureresearch-article20222022-07-01July 202210.2215/CJN.108808211555-90411555-905X2022-03-14T05:54:39-07:002022-07Clinical Journal of the American Society of NephrologyFeature17710821091Racial and Ethnic Disparities in Home Dialysis Use in the United States: Barriers and Solutions10.1681/ASN.2022030288Tue, 19 Apr 2022 09:24:58 GMT-07:00Racial and Ethnic Disparities in Home Dialysis Use in the United States: Barriers and SolutionsRizzolo, KatherineCervantes, LiliaShen, Jenny I.2022-04-19T09:24:58-07:00doi:10.1681/ASN.2022030288hwp:resource-id:jnephrol;33/7/1258American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of NephrologyPerspectiveSpecial Series on Addressing Racial and Ethnic Disparities in Kidney DiseasePerspectiveSpecial Series on Addressing Racial and Ethnic Disparities in Kidney Diseaseresearch-article20222022-07-01July 202210.1681/ASN.20220302881046-66731533-34502022-04-19T09:24:58-07:002022-07Journal of the American Society of NephrologyPerspective33712581261Culturally Concordant Community-Health Workers: Building Sustainable Community-Based Interventions that Eliminate Kidney Health Disparities10.1681/ASN.2022030319Tue, 26 Apr 2022 09:13:40 GMT-07:00Culturally Concordant Community-Health Workers: Building Sustainable Community-Based Interventions that Eliminate Kidney Health DisparitiesCervantes, LiliaRobinson, Bruce M.Steiner, John F.Myaskovsky, Larissa2022-04-26T09:13:40-07:00doi:10.1681/ASN.2022030319hwp:resource-id:jnephrol;33/7/1252American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologyracial and ethnic disparities, ethnicity, kidney disease, ethnic minorityPerspectiveSpecial Series on Addressing Racial and Ethnic Disparities in Kidney DiseasePerspectiveSpecial Series on Addressing Racial and Ethnic Disparities in Kidney Diseaseresearch-article20222022-07-01July 202210.1681/ASN.20220303191046-66731533-34502022-04-26T09:13:40-07:002022-07Journal of the American Society of NephrologyPerspective33712521254Ongoing Lessons from the Comprehensive ESRD Care Program10.34067/KID.0008142021Thu, 30 Jun 2022 06:00:22 GMT-07:00Ongoing Lessons from the Comprehensive ESRD Care ProgramKinlaw, Alan C.Kshirsagar, Abhijit V.2022-06-30T06:00:22-07:00doi:10.34067/KID.0008142021hwp:resource-id:kidney360;3/6/988American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, alternative payment model, ESRD, value based careEditorialEditorialeditorial20222022-06-3010.34067/KID.00081420212641-76502022-06-30T06:00:22-07:002022-06-30Kidney360Editorial36988990Utilization of Peritoneal Dialysis in the United States: Progress in Tackling Obstacles to ExpansionTo facilitate the desired increase in home dialysis utilization in the United States, multiple factors need to be taken into consideration in order to achieve this complex task. Through policy-level facilitators such as the Advancing American Kidney Health Initiative and the expansion of telehealth utilization, adjustments to the existing payment models, providing health equity incentives, increasing number of provider education materials on home therapies, and allaying patient fears with the expansion of home dialysis education nationwide, we have taken several steps in the right direction. There is still a long way to go, and further improvements can be made while utilizing lessons learned from some of our international peers who have been successful in their implementation of large-scale home dialysis programs.10.34067/KID.0001872022Fri, 15 Apr 2022 01:32:21 GMT-07:00Utilization of Peritoneal Dialysis in the United States: Progress in Tackling Obstacles to ExpansionTo facilitate the desired increase in home dialysis utilization in the United States, multiple factors need to be taken into consideration in order to achieve this complex task. Through policy-level facilitators such as the Advancing American Kidney Health Initiative and the expansion of telehealth utilization, adjustments to the existing payment models, providing health equity incentives, increasing number of provider education materials on home therapies, and allaying patient fears with the expansion of home dialysis education nationwide, we have taken several steps in the right direction. There is still a long way to go, and further improvements can be made while utilizing lessons learned from some of our international peers who have been successful in their implementation of large-scale home dialysis programs.El Shamy, Osama2022-04-15T13:32:21-07:00doi:10.34067/KID.0001872022hwp:resource-id:kidney360;3/6/1112American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, peritoneal dialysis, policy, racial disparities, United StatesReview ArticleReview Articlereview-article20222022-06-3010.34067/KID.00018720222641-76502022-04-15T13:32:21-07:002022-06-30Kidney360Review Article3611121117The Impact of COVID-19 on Postdischarge Outcomes for Dialysis Patients in the United States: Evidence from Medicare Claims Data10.34067/KID.0000242022Fri, 15 Apr 2022 01:32:21 GMT-07:00The Impact of COVID-19 on Postdischarge Outcomes for Dialysis Patients in the United States: Evidence from Medicare Claims DataWu, WenboGremel, Garrett W.He, KevinMessana, Joseph M.Sen, AnandaSegal, Jonathan H.Dahlerus, ClaudiaHirth, Richard A.Kang, JianWisniewski, KarenNahra, TammiePadilla, RobinTong, LanGu, HaoyuWang, XiSlowey, MeganEckard, AshleyDing, XuemeiBorowicz, LisaDu, JuanFrye, BrandonKalbfleisch, John D.2022-04-15T13:32:21-07:00doi:10.34067/KID.0000242022hwp:resource-id:kidney360;3/6/1047American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, aftercare, COVID-19, patient discharge, SARS-CoV-2, United StatesOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-06-3010.34067/KID.00002420222641-76502022-04-15T13:32:21-07:002022-06-30Kidney360Original Investigation3610471056Cost Barriers to More Widespread Use of Peritoneal Dialysis in the United StatesThe United States Department of Health and Human Services launched the Advancing American Kidney Health Initiative in 2019, which included a goal of transforming dialysis care from an in-center to a largely home-based dialysis program. A substantial motivator for this transition is the potential to reduce costs of ESKD care with peritoneal dialysis. Studies demonstrating that peritoneal dialysis is less costly than in-center hemodialysis have often focused on the perspective of the payer, whereas less consideration has been given to the costs of those who are more directly involved in treatment decision making, including patients, caregivers, physicians, and dialysis facilities. We review comparisons of peritoneal dialysis and in-center hemodialysis costs, focusing on costs incurred by the people and organizations making decisions about dialysis modality, to highlight the financial barriers toward increased adoption of peritoneal dialysis. We specifically address misaligned economic incentives, underappreciated costs for key stakeholders involved in peritoneal dialysis delivery, differences in provider costs, and transition costs. We conclude by offering policy suggestions that include improving data collection to better understand costs in peritoneal dialysis, and sharing potential savings among all stakeholders, to incentivize a transition to peritoneal dialysis.10.1681/ASN.2021060854Mon, 21 Mar 2022 08:02:49 GMT-07:00Cost Barriers to More Widespread Use of Peritoneal Dialysis in the United StatesThe United States Department of Health and Human Services launched the Advancing American Kidney Health Initiative in 2019, which included a goal of transforming dialysis care from an in-center to a largely home-based dialysis program. A substantial motivator for this transition is the potential to reduce costs of ESKD care with peritoneal dialysis. Studies demonstrating that peritoneal dialysis is less costly than in-center hemodialysis have often focused on the perspective of the payer, whereas less consideration has been given to the costs of those who are more directly involved in treatment decision making, including patients, caregivers, physicians, and dialysis facilities. We review comparisons of peritoneal dialysis and in-center hemodialysis costs, focusing on costs incurred by the people and organizations making decisions about dialysis modality, to highlight the financial barriers toward increased adoption of peritoneal dialysis. We specifically address misaligned economic incentives, underappreciated costs for key stakeholders involved in peritoneal dialysis delivery, differences in provider costs, and transition costs. We conclude by offering policy suggestions that include improving data collection to better understand costs in peritoneal dialysis, and sharing potential savings among all stakeholders, to incentivize a transition to peritoneal dialysis.Baerman, Elliot A.Kaplan, JenniferShen, Jenny I.Winkelmayer, Wolfgang C.Erickson, Kevin F.2022-03-21T08:02:49-07:00doi:10.1681/ASN.2021060854hwp:resource-id:jnephrol;33/6/1063American Society of NephrologyCopyright © 2022 by the American Society of NephrologyJournal of the American Society of Nephrologychronic dialysis, economic analysis, ESKD, peritoneal dialysis, United StatesUp Front MattersReviewUp Front MattersReviewreview-article20222022-06-01June 202210.1681/ASN.20210608541046-66731533-34502022-03-21T08:02:49-07:002022-06Journal of the American Society of NephrologyUp Front Matters336111063212510722126Hidden Costs Associated with Conversion from Peritoneal Dialysis to Hemodialysis10.34067/KID.0007692021Thu, 03 Mar 2022 06:46:18 GMT-08:00Hidden Costs Associated with Conversion from Peritoneal Dialysis to HemodialysisWeinhandl, Eric D.Saffer, Tonya L.Aragon, Michael2022-03-03T06:46:18-08:00doi:10.34067/KID.0007692021hwp:resource-id:kidney360;3/5/883American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, costs and cost analysis, hemodialysis, Medicare, peritoneal dialysis, technique failure, United States Renal Data SystemOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-05-2610.34067/KID.00076920212641-76502022-03-03T06:46:18-08:002022-05-26Kidney360Original Investigation35883890Is There an Ideal Recipe to Increase Home Dialysis Use?10.2215/CJN.02150222Mon, 21 Mar 2022 11:23:06 GMT-07:00Is There an Ideal Recipe to Increase Home Dialysis Use?Shen, Jenny I.Perl, Jeffrey2022-03-21T11:23:06-07:00doi:10.2215/CJN.02150222hwp:resource-id:clinjasn;17/4/484American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyhome dialysisEditorialEditorialeditorial20222022-04-01April 202210.2215/CJN.021502221555-90411555-905X2022-03-21T11:23:06-07:002022-04Clinical Journal of the American Society of NephrologyEditorial1744484535486545The Knowledge Assessment of Renal Transplantation (KART) 2.010.2215/CJN.11490821Thu, 24 Mar 2022 07:14:57 GMT-07:00The Knowledge Assessment of Renal Transplantation (KART) 2.0Waterman, Amy D.Nair, DevikaPurnajo, IntanCavanaugh, Kerri L.Mittman, Brian S.Peipert, John Devin2022-03-24T07:14:57-07:00doi:10.2215/CJN.11490821hwp:resource-id:clinjasn;17/4/555American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCKD, transplantation, knowledge, education, transplantsOriginal ArticleTransplantationOriginal ArticleTransplantationresearch-article20222022-04-01April 202210.2215/CJN.114908211555-90411555-905X2022-03-24T07:14:57-07:002022-04Clinical Journal of the American Society of NephrologyOriginal Article17444555473481564474483Multifaceted Intervention to Increase the Use of Home Dialysis10.2215/CJN.13191021Mon, 21 Mar 2022 11:07:36 GMT-07:00Multifaceted Intervention to Increase the Use of Home DialysisManns, Braden J.Garg, Amit X.Sood, Manish M.Ferguson, ThomasKim, S. JosephNaimark, DavidNesrallah, Gihad E.Soroka, Steven D.Beaulieu, MonicaDixon, Stephanie N.Alam, AhsanAllu, SelinaTangri, Navdeep2022-03-21T11:07:36-07:00doi:10.2215/CJN.13191021hwp:resource-id:clinjasn;17/4/535American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, randomized controlled trials, end stage kidney disease, peritoneal dialysis, home hemodialysisOriginal ArticleMaintenance DialysisOriginal ArticleMaintenance Dialysisresearch-article20222022-04-01April 202210.2215/CJN.131910211555-90411555-905X2022-03-21T11:07:36-07:002022-04Clinical Journal of the American Society of NephrologyOriginal Article1744535484545486Breaking the Barriers to Innovation in Kidney Care10.2215/CJN.15721221Tue, 15 Feb 2022 07:19:38 GMT-08:00Breaking the Barriers to Innovation in Kidney CareNissenson, Allen R.Chertow, Glenn M.Conway, Paul T.2022-02-15T07:19:38-08:00doi:10.2215/CJN.15721221hwp:resource-id:clinjasn;17/4/591American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic dialysis, kidney care, innovation, KidneyX, KHIPerspectivePerspectiveresearch-article20222022-04-01April 202210.2215/CJN.157212211555-90411555-905X2022-02-15T07:19:38-08:002022-04Clinical Journal of the American Society of NephrologyPerspective174591593Initial Home Dialysis Is Increased for Rural Patients by Accessing Urban Facilities10.34067/KID.0006932021Tue, 04 Jan 2022 05:02:17 GMT-08:00Initial Home Dialysis Is Increased for Rural Patients by Accessing Urban FacilitiesAdler, Joel T.Husain, S. AliXiang, LingweiRodrigue, James R.Waikar, Sushrut S.2022-01-04T17:02:17-08:00doi:10.34067/KID.0006932021hwp:resource-id:kidney360;3/3/488American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, chronic kidney disease, clinical nephrology, home dialysis, mortality gap, rural population, urban facilitiesOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-03-3110.34067/KID.00069320212641-76502022-01-04T17:02:17-08:002022-03-31Kidney360Original Investigation33488496Provision of Kidney Disease Education Service Is Associated with Improved Vascular Access Outcomes among US Incident Hemodialysis Patients10.34067/KID.0004502021Tue, 28 Sep 2021 01:12:16 GMT-07:00Provision of Kidney Disease Education Service Is Associated with Improved Vascular Access Outcomes among US Incident Hemodialysis PatientsRuchi, RupamBozorgmehri, ShahabChamarthi, GajapathirajuOrozco, TatianaMohandas, RajeshOzrazgat-Baslanti, TezcanSegal, Mark S.Shukla, Ashutosh M.2021-09-28T13:12:16-07:00doi:10.34067/KID.0004502021hwp:resource-id:kidney360;3/1/91American Society of NephrologyCopyright © 2022 by the American Society of NephrologyKidney360dialysis, arteriovenous access, arteriovenous fistula, arteriovenous graft, chronic dialysis, chronic hemodialysis, CKD, clinical nephrology, dialysis access, ESKD, hemodialysis accessOriginal InvestigationDialysisOriginal InvestigationDialysisresearch-article20222022-01-2710.34067/KID.00045020212641-76502021-09-28T13:12:16-07:002022-01-27Kidney360Original Investigation319198An Honorable and Ongoing Fight10.2215/CJN.15071121Wed, 22 Dec 2021 11:26:05 GMT-08:00An Honorable and Ongoing FightConway, Paul T.2021-12-22T11:26:05-08:00doi:10.2215/CJN.15071121hwp:resource-id:clinjasn;17/1/1American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney transplantation, nephrology, COVID-19, immunosuppressed, vaccines, vaccination, monoclonal antibodies, Delta variant, Kidney Health InitiativePatient VoicePatient Voiceeditorial20222022-01-01January 202210.2215/CJN.150711211555-90411555-905X2021-12-22T11:26:05-08:002022-01Clinical Journal of the American Society of NephrologyPatient Voice17111198321065Kidney Failure Risk Equation and Cost of Care in Patients with Chronic Kidney Disease10.2215/CJN.06770521Thu, 30 Dec 2021 10:48:48 GMT-08:00Kidney Failure Risk Equation and Cost of Care in Patients with Chronic Kidney DiseasePrasad, BhanuOsman, MericJafari, MaryamGordon, LexisTangri, NavdeepFerguson, Thomas W.Jin, ShanKappel, JoanneKozakewycz, Diane2021-12-30T10:48:48-08:00doi:10.2215/CJN.06770521hwp:resource-id:clinjasn;17/1/17American Society of NephrologyCopyright © 2022 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, economic analysis, renal insufficiencyOriginal ArticleChronic Kidney DiseaseOriginal ArticleChronic Kidney Diseaseresearch-article20222022-01-01January 202210.2215/CJN.067705211555-90411555-905X2021-12-30T10:48:48-08:002022-01Clinical Journal of the American Society of NephrologyOriginal Article171117142616Global Perspective on Kidney Transplantation: United States10.34067/KID.0002472021Thu, 19 Aug 2021 11:39:27 GMT-07:00Global Perspective on Kidney Transplantation: United StatesWang, Jeffrey H.Hart, Allyson2021-08-19T11:39:27-07:00doi:10.34067/KID.0002472021hwp:resource-id:kidney360;2/11/1836American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360transplantation, kidney transplant, United States, waitlistGlobal PerspectivesGlobal Perspectivesresearch-article20212021-11-2510.34067/KID.00024720212641-76502021-08-19T11:39:27-07:002021-11-25Kidney360Global Perspectives21118361839The Future Nephrology Workforce: There Will Be One10.2215/CJN.05040421Mon, 19 Jul 2021 10:54:28 GMT-07:00The Future Nephrology Workforce: There Will Be OneParker, Mark G.Sozio, Stephen M.2021-07-19T10:54:28-07:00doi:10.2215/CJN.05040421hwp:resource-id:clinjasn;16/11/1752American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyworkforce, nephrology training, nephrologyPerspectivePerspectiveresearch-article20212021-11-01November 202110.2215/CJN.050404211555-90411555-905X2021-07-19T10:54:28-07:002021-11Clinical Journal of the American Society of NephrologyPerspective161117521754Training Nephrology Fellows in Home Dialysis in the United States10.2215/CJN.03110321Wed, 21 Jul 2021 07:02:00 GMT-07:00Training Nephrology Fellows in Home Dialysis in the United StatesGupta, NupurMiller, Brent W.2021-07-21T07:02:00-07:00doi:10.2215/CJN.03110321hwp:resource-id:clinjasn;16/11/1749American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologynephrology, dialysis, Home DialysisPerspectivePerspectiveresearch-article20212021-11-01November 202110.2215/CJN.031103211555-90411555-905X2021-07-21T07:02:00-07:002021-11Clinical Journal of the American Society of NephrologyPerspective161117491751Value-Based Care in Nephrology: The Kidney Care Choices Model and Other ReformsThe Advancing American Kidney Health (AAKH) initiative has reinvigorated the focus on improving the care of patients with advanced CKD. Multiple interventions have been planned, focusing on education campaigns for both clinicians and patients, delaying the progression of kidney disease and improving utilization of home dialysis modalities and kidney transplantation. Value-based care models for patients with advanced kidney disease are being rolled out, with the ESKD treatment choices model starting in January 2021, and the Kidney Care Choices model planned to start in January 2022. There is increasing emphasis on the role of the nephrologist as the “captain of the ship,” leading efforts in care coordination as physician leaders. The transplant reforms have focused on changes to organ procurement organizations aiming to increase availability of organs, and transplants performed, both deceased and living donor, and removing financial disincentives from live organ donation. The American Society of Nephrology (ASN) and the National Kidney Foundation (NKF) are partnering with the Department of Health and Human Services to develop educational material for clinicians and patients. In this review, we discuss these reforms, potential challenges that have arisen, and potential solutions, with emphasis on the Kidney Care Choices model.10.34067/KID.0004552021Mon, 16 Aug 2021 10:48:11 GMT-07:00Value-Based Care in Nephrology: The Kidney Care Choices Model and Other ReformsThe Advancing American Kidney Health (AAKH) initiative has reinvigorated the focus on improving the care of patients with advanced CKD. Multiple interventions have been planned, focusing on education campaigns for both clinicians and patients, delaying the progression of kidney disease and improving utilization of home dialysis modalities and kidney transplantation. Value-based care models for patients with advanced kidney disease are being rolled out, with the ESKD treatment choices model starting in January 2021, and the Kidney Care Choices model planned to start in January 2022. There is increasing emphasis on the role of the nephrologist as the “captain of the ship,” leading efforts in care coordination as physician leaders. The transplant reforms have focused on changes to organ procurement organizations aiming to increase availability of organs, and transplants performed, both deceased and living donor, and removing financial disincentives from live organ donation. The American Society of Nephrology (ASN) and the National Kidney Foundation (NKF) are partnering with the Department of Health and Human Services to develop educational material for clinicians and patients. In this review, we discuss these reforms, potential challenges that have arisen, and potential solutions, with emphasis on the Kidney Care Choices model.Jain, GauravWeiner, Daniel E.2021-08-16T10:48:11-07:00doi:10.34067/KID.0004552021hwp:resource-id:kidney360;2/10/1677American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360clinical nephrology, chronic kidney disease, dialysis, ETC, KCC, kidney care choices, patient activation measure, value-based careReview ArticleReview Articlereview-article20212021-10-2810.34067/KID.00045520212641-76502021-08-16T10:48:11-07:002021-10-28Kidney360Review Article21016771683Organizational Characteristics Associated with High Performance in Medicare’s Comprehensive End-Stage Renal Disease Care Initiative10.2215/CJN.04020321Thu, 07 Oct 2021 12:05:16 GMT-07:00Organizational Characteristics Associated with High Performance in Medicare’s Comprehensive End-Stage Renal Disease Care InitiativeDrewry, Kelsey M.Trivedi, Amal N.Wilk, Adam S.2021-10-07T12:05:16-07:00doi:10.2215/CJN.04020321hwp:resource-id:clinjasn;16/10/1522American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic dialysis, clinical nephrology, dialysis, disparity, end stage kidney disease, end-stage renal disease, ESRD, hemodialysis, nephrology, comprehensive health careOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20212021-10-01October 202110.2215/CJN.040203211555-90411555-905X2021-10-07T12:05:16-07:002021-10Clinical Journal of the American Society of NephrologyOriginal Articles1610101522146715301469Transforming the Care of Patients with Diabetic Kidney DiseaseDiabetes and its associated complications pose an immediate threat to humankind. Diabetic kidney disease is one of the most devastating complications, increasing the risk of death more than ten-fold over the general population. Until very recently, the only drugs proven and recommended to slow the progression of diabetic kidney disease were angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers, which act by inhibiting the renin-angiotensin system. Despite their efficacy as kidney and cardiovascular protective therapies and as antihypertensive agents, renin-angiotensin system inhibitors have been grossly underutilized. Moreover, even when renin-angiotensin system inhibitors are used, patients still have a high residual risk of diabetic kidney disease progression. Finally, the kidney-protective effect of renin-angiotensin system inhibitors has been categorically demonstrated only in patients with macroalbuminuria included in the Irbesartan Diabetic Nephropathy Trial (IDNT) and Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trials, not in other individuals. The lack of new therapies to treat diabetic kidney disease over the past 2 decades has therefore represented a tremendous challenge for patients and health care providers alike. In recent years, a number of powerful new therapies have emerged that promise to transform care of patients with diabetes and kidney disease. The challenge to the community is to ensure rapid implementation of these treatments. This white paper highlights advances in treatment, opportunities for patients, challenges, and possible solutions to advance kidney health, and introduces the launch of the Diabetic Kidney Disease Collaborative at the American Society of Nephrology, to aid in accomplishing these goals.10.2215/CJN.18641120Tue, 08 Jun 2021 06:52:50 GMT-07:00Transforming the Care of Patients with Diabetic Kidney DiseaseDiabetes and its associated complications pose an immediate threat to humankind. Diabetic kidney disease is one of the most devastating complications, increasing the risk of death more than ten-fold over the general population. Until very recently, the only drugs proven and recommended to slow the progression of diabetic kidney disease were angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers, which act by inhibiting the renin-angiotensin system. Despite their efficacy as kidney and cardiovascular protective therapies and as antihypertensive agents, renin-angiotensin system inhibitors have been grossly underutilized. Moreover, even when renin-angiotensin system inhibitors are used, patients still have a high residual risk of diabetic kidney disease progression. Finally, the kidney-protective effect of renin-angiotensin system inhibitors has been categorically demonstrated only in patients with macroalbuminuria included in the Irbesartan Diabetic Nephropathy Trial (IDNT) and Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trials, not in other individuals. The lack of new therapies to treat diabetic kidney disease over the past 2 decades has therefore represented a tremendous challenge for patients and health care providers alike. In recent years, a number of powerful new therapies have emerged that promise to transform care of patients with diabetes and kidney disease. The challenge to the community is to ensure rapid implementation of these treatments. This white paper highlights advances in treatment, opportunities for patients, challenges, and possible solutions to advance kidney health, and introduces the launch of the Diabetic Kidney Disease Collaborative at the American Society of Nephrology, to aid in accomplishing these goals.Brosius, Frank C.Cherney, DavidGee, Patrick O.Harris, Raymond C.Kliger, Alan S.Tuttle, Katherine R.Quaggin, Susan E.2021-06-08T06:52:50-07:00doi:10.2215/CJN.18641120hwp:resource-id:clinjasn;16/10/1590American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydiabetes, kidney disease, SGLT2 inhibitor, disparity, equityReviewsReviewsreview-article20212021-10-01October 202110.2215/CJN.186411201555-90411555-905X2021-06-08T06:52:50-07:002021-10Clinical Journal of the American Society of NephrologyReviews161015901600Advancing American Kidney Health and the Role of Sodium-Glucose Cotransporter-2 Inhibitors10.2215/CJN.05450421Wed, 16 Jun 2021 10:53:39 GMT-07:00Advancing American Kidney Health and the Role of Sodium-Glucose Cotransporter-2 InhibitorsLi, JiahuaTummalapalli, Sri LekhaMendu, Mallika L.2021-06-16T10:53:39-07:00doi:10.2215/CJN.05450421hwp:resource-id:clinjasn;16/10/1584American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, United States, sodium-glucose transporter 2 inhibitors, diabetes mellitus, type 2, sodium-glucose transporter 2, proteinuria, SGLT2iPerspectivesPerspectivesresearch-article20212021-10-01October 202110.2215/CJN.054504211555-90411555-905X2021-06-16T10:53:39-07:002021-10Clinical Journal of the American Society of NephrologyPerspectives161015841586Patient Health Outcomes following Dialysis Facility Closures in the United States10.1681/ASN.2021020244Fri, 01 Oct 2021 10:51:44 GMT-07:00Patient Health Outcomes following Dialysis Facility Closures in the United StatesNiu, JingboSaeed, Maryam K.Winkelmayer, Wolfgang C.Erickson, Kevin F.2021-10-01T10:51:44-07:00doi:10.1681/ASN.2021020244hwp:resource-id:jnephrol;32/10/2613American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologyclinical nephrology, end stage kidney disease, epidemiology and outcomes, hemodialysis, United States Renal Data SystemClinical EpidemiologyClinical Epidemiologyresearch-article20212021-10-01October 202110.1681/ASN.20210202441046-66731533-34502021-10-01T10:51:44-07:002021-10Journal of the American Society of NephrologyClinical Epidemiology3210102613i2621iCOVID-19 among Adults Receiving Home versus In-Center Dialysis10.2215/CJN.04170321Fri, 04 Jun 2021 11:54:31 GMT-07:00COVID-19 among Adults Receiving Home versus In-Center DialysisPerl, JeffreyThomas, DonealTang, YiwenYeung, AngieIp, JaneOliver, Matthew J.Blake, Peter G.2021-06-04T11:54:31-07:00doi:10.2215/CJN.04170321hwp:resource-id:clinjasn;16/9/1410American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, hemodialysis, peritoneal dialysis, mortality risk, research design, cohort studiesResearch LettersResearch Lettersresearch-article20212021-09-01September 202110.2215/CJN.041703211555-90411555-905X2021-06-04T11:54:31-07:002021-09Clinical Journal of the American Society of NephrologyResearch Letters16914101412Keeping Dialysis Patients Safe10.2215/CJN.08090621Wed, 04 Aug 2021 06:10:08 GMT-07:00Keeping Dialysis Patients SafeWager, Roberta L.2021-08-04T06:10:08-07:00doi:10.2215/CJN.08090621hwp:resource-id:clinjasn;16/8/1141American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyCOVID-19, dialysisPatient VoicePatient Voiceresearch-article20212021-08-01August 202110.2215/CJN.080906211555-90411555-905X2021-08-04T06:10:08-07:002021-08Clinical Journal of the American Society of NephrologyPatient Voice16888114112371146114212461148Patient-Reported Experiences with Dialysis Care and Provider Visit Frequencykevin.erickson@bcm.edu10.2215/CJN.16621020Mon, 12 Jul 2021 07:54:45 GMT-07:00Patient-Reported Experiences with Dialysis Care and Provider Visit FrequencyBrady, Brian M.Zhao, BoDang, Bich N.Winkelmayer, Wolfgang C.Chertow, Glenn M.Erickson, Kevin F.2021-07-12T07:54:45-07:00doi:10.2215/CJN.16621020hwp:resource-id:clinjasn;16/7/1052American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyclinical nephrology, dialysis, epidemiology and outcomesOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20212021-07-01July 202110.2215/CJN.166210201555-90411555-905X2021-07-12T07:54:45-07:002021-07Clinical Journal of the American Society of NephrologyOriginal Articles16710521060Vaccine and the Need To Be Heard: Considerations for COVID-19 Immunization in ESKD10.34067/KID.0001932021Thu, 08 Apr 2021 01:50:57 GMT-07:00Vaccine and the Need To Be Heard: Considerations for COVID-19 Immunization in ESKDSrivatana, VeshWilkie, CarolinePerl, JefferyWatnick, Suzanne2021-04-08T13:50:57-07:00doi:10.34067/KID.0001932021hwp:resource-id:kidney360;2/6/1048American Society of NephrologyCopyright © 2021 by the American Society of NephrologyKidney360dialysis, COVID-19, vaccinePerspectivePerspectiveresearch-article20212021-06-2410.34067/KID.00019320212641-76502021-04-08T13:50:57-07:002021-06-24Kidney360Perspective2610481050Dialysis Facility Profit Status and Early Steps in Kidney Transplantation in the Southeastern United States10.2215/CJN.17691120Wed, 26 May 2021 02:21:46 GMT-07:00Dialysis Facility Profit Status and Early Steps in Kidney Transplantation in the Southeastern United StatesMcPherson, Laura J.Walker, Elizabeth R.Lee, Yi-Ting HanaGander, Jennifer C.Wang, ZhenshengReeves-Daniel, Amber M.Browne, TeriEllis, Matthew J.Rossi, Ana P.Pastan, Stephen O.Patzer, Rachel E.,,Adams, AngelaAdler, Joel ThomasAllison, CynthiaArnold, EmilyBaliga, PrabhakarBelmonte, KathleenBerlin, AlexanderBooth, EleanorBroughton, PaulBrowne, TeriCanavan, KelleyCaponi, SueCarter, RosalynCipriani, KatherynChikhliker, BlakelyClynes, DianaCoe, MarshiaCollins, BradleyCruz, AlexandreaDetwiler, RandyDuBay, DerekDubbs, JilDunn, DuaneEllis, MatthewEvans, DebraFarrell, JessicaFlemming, ShaunaFrance, NicoleFuller, EddieGander, Jennifer C.Gibney, EricGivens, JoVonnGodwin, NatalieGrace, TerryGraves, HannahGreen, GaryGulotta, JosephHayden, RobertHarding, JessicaHarrill, JenniferHeald, ChuckHill, MichelleHippen, BenHuml, AnneHumphry, RustyHymes, BenImundo, SandyArriola, Kimberly JacobJames, HeatherJohnson, DougJones, HeatherKahle, ErinKearns, LaurenKlemen, MarkKluge, LindaKnowles, LeahKozlowski, TomaszKrisher, JennaKutner, NancyLloyd, ScottLyman, LynnMalik, SanaMcCanna, LisaMcCorquodale, GriseldaMcKinney, CaraMcMath, SandyMcPherson, LauraMichaels, RitaMilfort, MargaretMohan, SumitMoore, LindaMorinelli, ThomasMoshiri, RebekahMuench, DoriMulloy, LauraMutell, RichNewsome, JessicaNiedfeldt, DanielleOliver, KathyPastan, StephenPatzer, RachelPaul, SudeshnaPerryman, JenniePilch, NicolePilgrim, JeaninePlantinga, LauraPorter, AliciaPriester, KarlaReeves-Daniel, AmberRetzloff, SamanthaRossi, AnaRudd, MartieSauls, LeighannScoggins, ToryScott, JohnSharp, JoeSimpkins, Carrie LynnStanton, DanielStone, CynthiaStone, MaureenStratta, BobTaber, DavidTaylor, RobertTeunis, LarissaThrasher, BrendaUrbanski, MeganVail, KimWaite, SueWang, ZhenshengWhite, KelleeWhite, KellyWhite, John JasonWhite, TyreeWiggins, ChristinaWilk, AdamWilliams, MyraWise, ElijahWoodard, AmyWright, ShannonZayas, CarlosZimmerman, Eddie2021-05-26T14:21:46-07:00doi:10.2215/CJN.17691120hwp:resource-id:clinjasn;16/6/926American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States Renal Data System, transplantation, kidney transplantation, epidemiology and outcomes, end stage kidney disease, dialysisOriginal ArticlesTransplantationOriginal ArticlesTransplantationresearch-article20212021-06-01June 202110.2215/CJN.176911201555-90411555-905X2021-05-26T14:21:46-07:002021-06Clinical Journal of the American Society of NephrologyOriginal Articles1666926846936847Measuring Patient Experience with Home Dialysis in the United States10.2215/CJN.01990221Tue, 30 Mar 2021 07:25:40 GMT-07:00Measuring Patient Experience with Home Dialysis in the United StatesBrady, Brian M.Kurella Tamura, Manjula2021-03-30T07:25:40-07:00doi:10.2215/CJN.01990221hwp:resource-id:clinjasn;16/4/508American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologydialysisEditorialsEditorialseditorial20212021-04-07April 07, 202110.2215/CJN.019902211555-90411555-905X2021-03-30T07:25:40-07:002021-04-07Clinical Journal of the American Society of NephrologyEditorials16444508497588510498598Legitimization and Incorporation of Patient Preferences10.2215/CJN.11780720Wed, 03 Mar 2021 06:28:26 GMT-08:00Legitimization and Incorporation of Patient PreferencesConway, Paul T.Knight, Richard2021-03-03T06:28:26-08:00doi:10.2215/CJN.11780720hwp:resource-id:clinjasn;16/4/645American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologypatient preference information, patient insights, Kidney Precision Medicine Project, FDA, Kidney Health Initiative, KidneyX, NIH, patient engagement, advancing American kidney healthPerspectivesPerspectivesresearch-article20212021-04-07April 07, 202110.2215/CJN.117807201555-90411555-905X2021-03-03T06:28:26-08:002021-04-07Clinical Journal of the American Society of NephrologyPerspectives1644444645634636639642647635638641644Failure to Advance Access to Kidney Transplantation over Two Decades in the United States10.1681/ASN.2020060888Thu, 11 Feb 2021 11:40:05 GMT-08:00Failure to Advance Access to Kidney Transplantation over Two Decades in the United StatesSchold, Jesse D.Mohan, SumitHuml, AnneBuccini, Laura D.Sedor, John R.Augustine, Joshua J.Poggio, Emilio D.2021-02-11T11:40:05-08:00doi:10.1681/ASN.2020060888hwp:resource-id:jnephrol;32/4/913American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, end-stage renal disease, risk factorsClinical EpidemiologyClinical Epidemiologyresearch-article20212021-04-01April 202110.1681/ASN.20200608881046-66731533-34502021-02-11T11:40:05-08:002021-04Journal of the American Society of NephrologyClinical Epidemiology324913926Children with CKD Are Not Little Adults with CKD10.2215/CJN.11540720Thu, 15 Oct 2020 06:51:39 GMT-07:00Children with CKD Are Not Little Adults with CKDKula, Alexander J.Somers, Michael J.G.,2020-10-15T06:51:39-07:00doi:10.2215/CJN.11540720hwp:resource-id:clinjasn;16/3/470American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyAAKH, pediatric nephrology, advocacy, chronic kidney disease, childrenPerspectivesPerspectivesresearch-article20212021-03-08March 08, 202110.2215/CJN.115407201555-90411555-905X2020-10-15T06:51:39-07:002021-03-08Clinical Journal of the American Society of NephrologyPerspectives163470472Advancing NephrologyNew treatments, new understanding, and new approaches to translational research are transforming the outlook for patients with kidney diseases. A number of new initiatives dedicated to advancing the field of nephrology—from value-based care to prize competitions—will further improve outcomes of patients with kidney disease. Because of individual nephrologists and kidney organizations in the United States, such as the American Society of Nephrology, the National Kidney Foundation, and the Renal Physicians Association, and international nephrologists and organizations, such as the International Society of Nephrology and the European Renal Association–European Dialysis and Transplant Association, we are beginning to gain traction to invigorate nephrology to meet the pandemic of global kidney diseases. Recognizing the timeliness of this opportunity, the American Society of Nephrology convened a Division Chief Retreat in Dallas, Texas, in June 2019 to address five key issues: (1) asserting the value of nephrology to the health system; (2) productivity and compensation; (3) financial support of faculty’s and divisions’ educational efforts; (4) faculty recruitment, retention, diversity, and inclusion; and (5) ensuring that fellowship programs prepare trainees to provide high-value nephrology care and enhance attraction of trainees to nephrology. Herein, we highlight the outcomes of these discussions and recommendations to the American Society of Nephrology.10.2215/CJN.01550220Wed, 12 Aug 2020 05:47:51 GMT-07:00Advancing NephrologyNew treatments, new understanding, and new approaches to translational research are transforming the outlook for patients with kidney diseases. A number of new initiatives dedicated to advancing the field of nephrology—from value-based care to prize competitions—will further improve outcomes of patients with kidney disease. Because of individual nephrologists and kidney organizations in the United States, such as the American Society of Nephrology, the National Kidney Foundation, and the Renal Physicians Association, and international nephrologists and organizations, such as the International Society of Nephrology and the European Renal Association–European Dialysis and Transplant Association, we are beginning to gain traction to invigorate nephrology to meet the pandemic of global kidney diseases. Recognizing the timeliness of this opportunity, the American Society of Nephrology convened a Division Chief Retreat in Dallas, Texas, in June 2019 to address five key issues: (1) asserting the value of nephrology to the health system; (2) productivity and compensation; (3) financial support of faculty’s and divisions’ educational efforts; (4) faculty recruitment, retention, diversity, and inclusion; and (5) ensuring that fellowship programs prepare trainees to provide high-value nephrology care and enhance attraction of trainees to nephrology. Herein, we highlight the outcomes of these discussions and recommendations to the American Society of Nephrology.Braden, Gregory L.Chapman, ArleneEllison, David H.Gadegbeku, Crystal A.Gurley, Susan B.Igarashi, PeterKelepouris, EllieMoxey-Mims, Marva M.Okusa, Mark D.Plumb, Troy J.Quaggin, Susan E.Salant, David J.Segal, Mark S.Shankland, Stuart J.Somlo, Stefan2020-08-12T05:47:51-07:00doi:10.2215/CJN.01550220hwp:resource-id:clinjasn;16/2/319American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of NephrologyWork Force, Nephrology Fellowship, Medical Education, KidneyX, Physician Productivity, DiversityFeaturesFeaturesresearch-article20212021-02-08February 08, 202110.2215/CJN.015502201555-90411555-905X2020-08-12T05:47:51-07:002021-02-08Clinical Journal of the American Society of NephrologyFeatures162319327Is It Time for Precision Dialysis?10.2215/CJN.08610520Fri, 18 Sep 2020 10:25:18 GMT-07:00Is It Time for Precision Dialysis?Gupta, NupurWish, Jay B.2020-09-18T10:25:18-07:00doi:10.2215/CJN.08610520hwp:resource-id:clinjasn;16/2/316American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney replacement therapy, payment models, chronic kidney disease, shared decision making, end stage kidney disease, dialysisPerspectivesPerspectivesresearch-article20212021-02-08February 08, 202110.2215/CJN.086105201555-90411555-905X2020-09-18T10:25:18-07:002021-02-08Clinical Journal of the American Society of NephrologyPerspectives162316318Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the United States: A Comparison of International Transplant Practices and Outcomes10.1681/ASN.2020040464Tue, 15 Dec 2020 09:50:57 GMT-08:00Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the United States: A Comparison of International Transplant Practices and OutcomesReese, Peter P.Aubert, OlivierNaesens, MaartenHuang, EdmundPotluri, VishnuKuypers, DirkBouquegneau, AntoineDivard, GillianRaynaud, MarcBouatou, YassineVo, AshleyGlotz, DenisLegendre, ChristopheLefaucheur, CarmenJordan, StanleyEmpana, Jean-PhilippeJouven, XavierLoupy, Alexandre2020-12-15T09:50:57-08:00doi:10.1681/ASN.2020040464hwp:resource-id:jnephrol;32/2/397American Society of NephrologyCopyright © 2021 by the American Society of NephrologyJournal of the American Society of Nephrologykidney biopsy, transplant outcomes, kidney transplantation, epidemiology and outcomes, pathologyClinical EpidemiologyClinical Epidemiologyresearch-article20212021-02-01February 202110.1681/ASN.20200404641046-66731533-34502020-12-15T09:50:57-08:002021-02Journal of the American Society of NephrologyClinical Epidemiology322553971263126440912641265Incremental and Twice-Weekly Hemodialysis Program in Practice10.2215/CJN.04170320Tue, 22 Sep 2020 12:25:26 GMT-07:00Incremental and Twice-Weekly Hemodialysis Program in PracticeMurea, MarianaKalantar-Zadeh, Kamyar2020-09-22T12:25:26-07:00doi:10.2215/CJN.04170320hwp:resource-id:clinjasn;16/1/147American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyincremental dialysis, residual kidney function, precision medicine, patient centeredness, hemodialysis, acute kidney injuryPerspectivesPerspectivesresearch-article20212021-01-07January 07, 202110.2215/CJN.041703201555-90411555-905X2020-09-22T12:25:26-07:002021-01-07Clinical Journal of the American Society of NephrologyPerspectives161147149Patients with Kidney Disease: Ready to Use Smartphones for Health Care Delivery?10.2215/CJN.17771120Tue, 22 Dec 2020 08:10:24 GMT-08:00Patients with Kidney Disease: Ready to Use Smartphones for Health Care Delivery?Schmidt, Lana2020-12-22T08:10:24-08:00doi:10.2215/CJN.17771120hwp:resource-id:clinjasn;16/1/1American Society of NephrologyCopyright © 2021 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, chronic kidney failure, kidney failure, dialysis, Delivery of Health Care, smartphonePatient VoicePatient Voiceeditorial20212021-01-07January 7, 202110.2215/CJN.177711201555-90411555-905X2020-12-22T08:10:24-08:002021-01-07Clinical Journal of the American Society of NephrologyPatient Voice1611119812210613Beta-2 Microglobulin Amyloidosis: Past, Present, and FutureAlmost half a century has elapsed since the first description of dialysis-related amyloidosis (DRA), a disorder caused by excessive accumulation of β-2 microglobulin (B2M). Within that period, substantial advances in RRT occurred. These improvements have led to a decrease in the incidence of DRA. In many countries, DRA is considered a “disappearing act” or complication. Although the prevalence of patients living with RRT increases, not all will have access to kidney transplantation. Consequently, the number of patients requiring interventions for treatment of DRA is postulated to increase. This postulate has been borne out in Japan, where the number of patients with ESKD requiring surgery for carpal tunnel continues to increase. Clinicians treating patients with ESKD have treatment options to improve B2M clearance; however, there is a need to identify ways to translate improved B2M clearance into improved quality of life for patients undergoing long-term dialysis.10.34067/KID.0004922020Wed, 21 Oct 2020 11:24:32 GMT-07:00Beta-2 Microglobulin Amyloidosis: Past, Present, and FutureAlmost half a century has elapsed since the first description of dialysis-related amyloidosis (DRA), a disorder caused by excessive accumulation of β-2 microglobulin (B2M). Within that period, substantial advances in RRT occurred. These improvements have led to a decrease in the incidence of DRA. In many countries, DRA is considered a “disappearing act” or complication. Although the prevalence of patients living with RRT increases, not all will have access to kidney transplantation. Consequently, the number of patients requiring interventions for treatment of DRA is postulated to increase. This postulate has been borne out in Japan, where the number of patients with ESKD requiring surgery for carpal tunnel continues to increase. Clinicians treating patients with ESKD have treatment options to improve B2M clearance; however, there is a need to identify ways to translate improved B2M clearance into improved quality of life for patients undergoing long-term dialysis.Portales-Castillo, IgnacioYee, JerryTanaka, HiroshiFenves, Andrew Z.2020-10-21T11:24:32-07:00doi:10.34067/KID.0004922020hwp:resource-id:kidney360;1/12/1447American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, advanced glycosylation, amyloidosis, beta-2-microglobulin, carpal tunnel, dialysis, hemofiltration, microglobulin, spondyloarthropathy, tenosynovitisReview ArticlesReview Articlesreview-article20202020-12-3110.34067/KID.00049220202641-76502020-10-21T11:24:32-07:002020-12-31Kidney360Review Articles11214471455The Role of Incremental Peritoneal Dialysis in the Era of the Advancing American Kidney Health Initiative10.2215/CJN.03960320Fri, 24 Jul 2020 07:39:49 GMT-07:00The Role of Incremental Peritoneal Dialysis in the Era of the Advancing American Kidney Health InitiativeReddy, Yuvaram N.V.Mendu, Mallika L.2020-07-24T07:39:49-07:00doi:10.2215/CJN.03960320hwp:resource-id:clinjasn;15/12/1835American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, economic impact, end stage kidney disease, end-stage renal disease, peritoneal dialysis, peritoneal membrane, kidneyPerspectivesPerspectivesresearch-article20202020-12-07December 07, 202010.2215/CJN.039603201555-90411555-905X2020-07-24T07:39:49-07:002020-12-07Clinical Journal of the American Society of NephrologyPerspectives151218351837Stepping into the Void10.2215/CJN.04660420Thu, 09 Jul 2020 07:55:51 GMT-07:00Stepping into the VoidAgarwal, AnupamIbrahim, Tod2020-07-09T07:55:51-07:00doi:10.2215/CJN.04660420hwp:resource-id:clinjasn;15/12/1832American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of NephrologyNephrologists physician compensation, kidney organizationsPerspectivesPerspectivesresearch-article20202020-12-07December 07, 202010.2215/CJN.046604201555-90411555-905X2020-07-09T07:55:51-07:002020-12-07Clinical Journal of the American Society of NephrologyPerspectives151271832105318341055Advancing American Kidney Health (AAKH): Catalyst for Investment in Kidney Diseases Clinical Trials and Precision Medicine10.2215/CJN.03660320Wed, 05 Aug 2020 10:14:28 GMT-07:00Advancing American Kidney Health (AAKH): Catalyst for Investment in Kidney Diseases Clinical Trials and Precision MedicineFowler, Kevin John2020-08-05T10:14:28-07:00doi:10.2215/CJN.03660320hwp:resource-id:clinjasn;15/12/1689American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of NephrologyACE inhibitors, African Americans, African American Study of Kidney Disease and Hypertension, clinical trials, precision medicine, upstream interventions, in-center hemodialysisPatient VoicesPatient Voicesresearch-article20202020-12-07December 07, 202010.2215/CJN.036603201555-90411555-905X2020-08-05T10:14:28-07:002020-12-07Clinical Journal of the American Society of NephrologyPatient Voices151216891691Accountable Care Organizations and Spending for Patients Undergoing Long-Term Dialysis10.2215/CJN.02150220Tue, 24 Nov 2020 08:11:47 GMT-08:00Accountable Care Organizations and Spending for Patients Undergoing Long-Term DialysisBakre, ShivaniHollingsworth, John M.Yan, Phyllis L.Lawton, Emily J.Hirth, Richard A.Shahinian, Vahakn B.2020-11-24T08:11:47-08:00doi:10.2215/CJN.02150220hwp:resource-id:clinjasn;15/12/1777American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologylong-term dialysis, Medicare, Accountable Care OrganizationsOriginal ArticlesMaintenance DialysisOriginal ArticlesMaintenance Dialysisresearch-article20202020-12-07December 07, 202010.2215/CJN.021502201555-90411555-905X2020-11-24T08:11:47-08:002020-12-07Clinical Journal of the American Society of NephrologyOriginal Articles1512121777169917841701Major Variation across Local Transplant Centers in Probability of Kidney Transplant for Wait-Listed Patients10.1681/ASN.2020030335Fri, 09 Oct 2020 11:47:02 GMT-07:00Major Variation across Local Transplant Centers in Probability of Kidney Transplant for Wait-Listed PatientsKing, Kristen L.Husain, S. AliSchold, Jesse D.Patzer, Rachel E.Reese, Peter P.Jin, ZhezhenRatner, Lloyd E.Cohen, David J.Pastan, Stephen O.Mohan, Sumit2020-10-09T11:47:02-07:00doi:10.1681/ASN.2020030335hwp:resource-id:jnephrol;31/12/2900American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, organ allocation, patient preferences, shared decision-making, health policyClinical EpidemiologyClinical Epidemiologyresearch-article20202020-12-01December 202010.1681/ASN.20200303351046-66731533-34502020-10-09T11:47:02-07:002020-12Journal of the American Society of NephrologyClinical Epidemiology311229002911Health Policy for Dialysis Care in Canada and the United StatesContemporary dialysis treatment for chronic kidney failure is complex, is associated with poor clinical outcomes, and leads to high health costs, all of which pose substantial policy challenges. Despite similar policy goals and universal access for their kidney failure programs, the United States and Canada have taken very different approaches to dealing with these challenges. While US dialysis care is primarily government funded and delivered predominantly by private for-profit providers, Canadian dialysis care is also government funded but delivered almost exclusively in public facilities. Differences also exist for regulatory mechanisms and the policy incentives that may influence the behavior of providers and facilities. These differences in health policy are associated with significant variation in clinical outcomes: mortality among patients on dialysis is consistently lower in Canada than in the United States, although the gap has narrowed in recent years. The observed heterogeneity in policy and outcomes offers important potential opportunities for each health system to learn from the other. This article compares and contrasts transnational dialysis-related health policies, focusing on key levers including payment, finance, regulation, and organization. We also describe how policy levers can incentivize favorable practice patterns to support high-quality/high-value, person-centered care and to catalyze the emergence of transformative technologies for alternative kidney replacement strategies.10.2215/CJN.14961219Thu, 25 Jun 2020 10:36:32 GMT-07:00Health Policy for Dialysis Care in Canada and the United StatesContemporary dialysis treatment for chronic kidney failure is complex, is associated with poor clinical outcomes, and leads to high health costs, all of which pose substantial policy challenges. Despite similar policy goals and universal access for their kidney failure programs, the United States and Canada have taken very different approaches to dealing with these challenges. While US dialysis care is primarily government funded and delivered predominantly by private for-profit providers, Canadian dialysis care is also government funded but delivered almost exclusively in public facilities. Differences also exist for regulatory mechanisms and the policy incentives that may influence the behavior of providers and facilities. These differences in health policy are associated with significant variation in clinical outcomes: mortality among patients on dialysis is consistently lower in Canada than in the United States, although the gap has narrowed in recent years. The observed heterogeneity in policy and outcomes offers important potential opportunities for each health system to learn from the other. This article compares and contrasts transnational dialysis-related health policies, focusing on key levers including payment, finance, regulation, and organization. We also describe how policy levers can incentivize favorable practice patterns to support high-quality/high-value, person-centered care and to catalyze the emergence of transformative technologies for alternative kidney replacement strategies.Tonelli, MarcelloVanholder, RaymondHimmelfarb, Jonathan2020-06-25T10:36:32-07:00doi:10.2215/CJN.14961219hwp:resource-id:clinjasn;15/11/1669American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, health policy, innovation, transnational comparisons, Kidney Failure, Chronic, peritoneal dialysis, Renal Insufficiency, Health Care Costs, GovernmentFeatureFeatureresearch-article20202020-11-06November 06, 202010.2215/CJN.149612191555-90411555-905X2020-06-25T10:36:32-07:002020-11-06Clinical Journal of the American Society of NephrologyFeature151116691677Global Dialysis Perspective: United States10.34067/KID.0001602020Fri, 14 Aug 2020 01:41:13 GMT-07:00Global Dialysis Perspective: United StatesHan, YunSaran, Rajiv2020-08-14T13:41:13-07:00doi:10.34067/KID.0001602020hwp:resource-id:kidney360;1/10/1137American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, Centers for Medicaid and Medicare, kidney registry, prospective payment system, surveillance, United States Renal Data SystemGlobal PerspectivesGlobal Perspectivesresearch-article20202020-10-2910.34067/KID.00016020202641-76502020-08-14T13:41:13-07:002020-10-29Kidney360Global Perspectives11011371142Toward Patient-Centered InnovationIndividuals with dialysis-dependent kidney failure experience considerable disease- and treatment-related decline in functional status and overall well-being. Despite these experiences, there have been few substantive technological advances in KRT in decades. As such, new federal initiatives seek to accelerate innovation. Historically, integration of patient perspectives into KRT product development has been limited. However, the US Food and Drug Administration recognizes the importance of incorporating patient perspectives into the total product life cycle (i.e., from product conception to postmarket surveillance) and encourages the consideration of patient-reported outcomes in regulatory-focused clinical trials when appropriate. Recognizing the significance of identifying patient-reported outcome measures (PROMs) that capture contemporary patient priorities, the Kidney Health Initiative, a public–private partnership between the American Society of Nephrology and US Food and Drug Administration, convened a workgroup to (1) develop a conceptual framework for a health-related quality of life PROM; (2) identify and map existing PROMs to the conceptual framework, prioritizing them on the basis of their supporting evidence for use in the regulatory environment; and (3) describe next steps for identifying PROMs for use in regulatory clinical trials of transformative KRT devices. This paper summarizes the proposed health-related quality-of-life PROM conceptual framework, maps and prioritizes PROMs, and identifies gaps and future needs to advance the development of rigorous, meaningful PROMS for use in clinical trials of transformative KRT devices.10.2215/CJN.00110120Fri, 10 Apr 2020 09:20:11 GMT-07:00Toward Patient-Centered InnovationIndividuals with dialysis-dependent kidney failure experience considerable disease- and treatment-related decline in functional status and overall well-being. Despite these experiences, there have been few substantive technological advances in KRT in decades. As such, new federal initiatives seek to accelerate innovation. Historically, integration of patient perspectives into KRT product development has been limited. However, the US Food and Drug Administration recognizes the importance of incorporating patient perspectives into the total product life cycle (i.e., from product conception to postmarket surveillance) and encourages the consideration of patient-reported outcomes in regulatory-focused clinical trials when appropriate. Recognizing the significance of identifying patient-reported outcome measures (PROMs) that capture contemporary patient priorities, the Kidney Health Initiative, a public–private partnership between the American Society of Nephrology and US Food and Drug Administration, convened a workgroup to (1) develop a conceptual framework for a health-related quality of life PROM; (2) identify and map existing PROMs to the conceptual framework, prioritizing them on the basis of their supporting evidence for use in the regulatory environment; and (3) describe next steps for identifying PROMs for use in regulatory clinical trials of transformative KRT devices. This paper summarizes the proposed health-related quality-of-life PROM conceptual framework, maps and prioritizes PROMs, and identifies gaps and future needs to advance the development of rigorous, meaningful PROMS for use in clinical trials of transformative KRT devices.Flythe, Jennifer E.Hilliard, Tandrea S.Ikeler, KourtneyKeller, SanGipson, Debbie S.Grandinetti, Amanda C.Nordyke, Robert J.Perrone, Ronald D.Roy-Chaudhury, PrabirUnruh, MarkWest, MelissaBocell, FraserHurst, Frank P.2020-04-10T09:20:11-07:00doi:10.2215/CJN.00110120hwp:resource-id:clinjasn;15/10/1522American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologypatient-reported outcomes, medical devices, innovation, dialysis, hemodialysis, end-stage renal disease, patient priorities, clinical trial, renal dialysis, quality of life, Public-Private Sector Partnerships, United States Food and Drug Administration, Patient Reported Outcome Measures, Renal Insufficiency, Renal Replacement Therapy, kidney, Patient-Centered CareFeaturesFeaturesresearch-article20202020-10-07October 07, 202010.2215/CJN.001101201555-90411555-905X2020-04-10T09:20:11-07:002020-10-07Clinical Journal of the American Society of NephrologyFeatures151015221530Screening and Recognition of Chronic Kidney Disease in VA Health Care System Primary Care Clinics10.34067/KID.0000532020Thu, 09 Jul 2020 10:01:15 GMT-07:00Screening and Recognition of Chronic Kidney Disease in VA Health Care System Primary Care ClinicsBansal, ShwetaMader, MichaelPugh, Jacqueline A.2020-07-09T10:01:15-07:00doi:10.34067/KID.0000532020hwp:resource-id:kidney360;1/9/904American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360chronic kidney disease, awareness, diuretics, glomerular filtration rate, hypertension, International Classification of Diseases, kidney function tests, renal insufficiency, chronic, retrospective studies, screening, urinalysis, proteinuria, albuminuriaOriginal InvestigationsChronic Kidney DiseaseOriginal InvestigationsChronic Kidney Diseaseresearch-article20202020-09-2410.34067/KID.00005320202641-76502020-07-09T10:01:15-07:002020-09-24Kidney360Original Investigations19904915Increasing Peritoneal Dialysis Use in Response to the COVID-19 Pandemic: Will It Go Viral?10.1681/ASN.2020050729Mon, 03 Aug 2020 08:33:52 GMT-07:00Increasing Peritoneal Dialysis Use in Response to the COVID-19 Pandemic: Will It Go Viral?Brown, Edwina A.Perl, Jeffrey2020-08-03T08:33:52-07:00doi:10.1681/ASN.2020050729hwp:resource-id:jnephrol;31/9/1928American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologyperitoneal dialysis, COVID-19, home dialysisPerspectivesPerspectivesresearch-article20202020-09-01September 202010.1681/ASN.20200507291046-66731533-34502020-08-03T08:33:52-07:002020-09Journal of the American Society of NephrologyPerspectives31919281930Presidential Address Kidney Week 2019The American Society of Nephrology Presidential Address was delivered by Mark Rosenberg at Kidney Week 2019 on November 7, 2019 in Washington, DC. The Address describes a remarkable alignment—a syzygy of policy, science, innovation accelerators, clinical trials, clinical care delivery, and activated patients—that exists today in the kidney space. As a community, we must ensure that the strategies developed to take advantage of this alignment, such as Advancing American Kidney Health, succeed. We must overcome our current challenges to thrive as a meaningful specialty. We have an incredible opportunity to come together as a kidney community to ensure success that realigns the priorities and incentives in kidney medicine to better achieve kidney health for all people throughout the world. The time is now to act.10.2215/CJN.15011219Tue, 24 Mar 2020 07:47:32 GMT-07:00Presidential Address Kidney Week 2019The American Society of Nephrology Presidential Address was delivered by Mark Rosenberg at Kidney Week 2019 on November 7, 2019 in Washington, DC. The Address describes a remarkable alignment—a syzygy of policy, science, innovation accelerators, clinical trials, clinical care delivery, and activated patients—that exists today in the kidney space. As a community, we must ensure that the strategies developed to take advantage of this alignment, such as Advancing American Kidney Health, succeed. We must overcome our current challenges to thrive as a meaningful specialty. We have an incredible opportunity to come together as a kidney community to ensure success that realigns the priorities and incentives in kidney medicine to better achieve kidney health for all people throughout the world. The time is now to act.Rosenberg, Mark E.2020-03-24T07:47:32-07:00doi:10.2215/CJN.15011219hwp:resource-id:clinjasn;15/8/1213American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, kidney, kidney failure, nephrology, transplantation, policy, kidney diseases, patientparticipationFeaturesFeaturesresearch-article20202020-08-07August 07, 202010.2215/CJN.150112191555-90411555-905X2020-03-24T07:47:32-07:002020-08-07Clinical Journal of the American Society of NephrologyFeatures15812131219Foreign Perspective on Achieving a Successful Peritoneal Dialysis-First Program10.34067/KID.0000712019Wed, 13 May 2020 01:27:03 GMT-07:00Foreign Perspective on Achieving a Successful Peritoneal Dialysis-First ProgramLi, Philip Kam-TaoRosenberg, Mark E.2020-05-13T13:27:03-07:00doi:10.34067/KID.0000712019hwp:resource-id:kidney360;1/7/680American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, cost-benefit analysis, hemodialysis, home, Hong Kong, kidney failure, chronic, PD-first policy, peritoneal dialysis, peritoneal dialysis, continuous ambulatory, renal insufficiency, chronic, renal replacement therapy, United StatesGlobal PerspectivesGlobal Perspectivesresearch-article20202020-07-3010.34067/KID.00007120192641-76502020-05-13T13:27:03-07:002020-07-30Kidney360Global Perspectives17680684Nephrology Nomenclature: How to Accelerate Patient Anxiety, Suppress Engagement, and Mire the Advance of Medical Innovation10.2215/CJN.08730620Thu, 25 Jun 2020 10:36:32 GMT-07:00Nephrology Nomenclature: How to Accelerate Patient Anxiety, Suppress Engagement, and Mire the Advance of Medical InnovationConway, Paul T.2020-06-25T10:36:32-07:00doi:10.2215/CJN.08730620hwp:resource-id:clinjasn;15/7/907American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of NephrologyAnxiety, Kidney Precision Medicine Project, KidneyX, Kidney Health Initiative, Patient Engagement, Advancing American Kidney Health, Pre-Dialysis, CKD stages, End Stage Renal Disease, Communication, Education, Nomenclature, Patient-Centered Care, Chronic Kidney Disease, Caregivers, Focus Groups, Judgment, Self-Management, Ownership, Language, Prognosis, Personal Satisfaction, Renal Insufficiency, Chronic, Kidney Failure, Chronic, Decision Making, Patient Participation, Fear, Patient-Centered CarePatient VoicePatient Voiceeditorial20202020-07-01July 01, 202010.2215/CJN.087306201555-90411555-905X2020-06-25T10:36:32-07:002020-07-01Clinical Journal of the American Society of NephrologyPatient Voice15777907937914908948916Understanding Work10.2215/CJN.12661019Mon, 24 Feb 2020 09:10:56 GMT-08:00Understanding WorkRosner, Mitchell HowardFalk, Ronald J.2020-02-24T09:10:56-08:00doi:10.2215/CJN.12661019hwp:resource-id:clinjasn;15/7/1053American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of Nephrologyproductivity, relative value unit, benchmark, aged, humans, United States, relative value scales, current procedural terminology, U.S. Centers for Medicare and Medicaid Services, American Medical Association, nephrology, Medicaid, Medicare, efficiency, physicians, office visits, malpractice, renal dialysis, fibrinogenPerspectivesPerspectivesresearch-article20202020-07-01July 01, 202010.2215/CJN.126610191555-90411555-905X2020-02-24T09:10:56-08:002020-07-01Clinical Journal of the American Society of NephrologyPerspectives157121053183210551834Health Care Costs by Type of Expenditure across eGFR Stages among Patients with and without Diabetes, Cardiovascular Disease, and Heart Failure10.1681/ASN.2019121308Tue, 02 Jun 2020 09:18:14 GMT-07:00Health Care Costs by Type of Expenditure across eGFR Stages among Patients with and without Diabetes, Cardiovascular Disease, and Heart FailureNichols, Gregory A.Ustyugova, AnastasiaDéruaz-Luyet, AnoukO’Keeffe-Rosetti, MaureenBrodovicz, Kimberly G.2020-06-02T09:18:14-07:00doi:10.1681/ASN.2019121308hwp:resource-id:jnephrol;31/7/1594American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologychronic kidney disease, Economic Impact, Epidemiology and outcomesClinical EpidemiologyClinical Epidemiologyresearch-article20202020-07-01July 202010.1681/ASN.20191213081046-66731533-34502020-06-02T09:18:14-07:002020-07Journal of the American Society of NephrologyClinical Epidemiology31715941601The Advancing American Kidney Health (AAKH) Executive Order: Promise and Caveats for Expanding Access to Kidney Transplantation10.34067/KID.0001172020Wed, 22 Apr 2020 01:45:16 GMT-07:00The Advancing American Kidney Health (AAKH) Executive Order: Promise and Caveats for Expanding Access to Kidney TransplantationLentine, Krista L.Mannon, Roslyn B.2020-04-22T13:45:16-07:00doi:10.34067/KID.0001172020hwp:resource-id:kidney360;1/6/557American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360transplantation, access, advocacy, compensation, donor, organs, transplantPerspectivesPerspectivesresearch-article20202020-06-2510.34067/KID.00011720202641-76502020-04-22T13:45:16-07:002020-06-25Kidney360Perspectives16557560Setting Up and Expanding a Home Dialysis Program: Is There a Recipe for Success?Home dialysis modalities remain significantly underused in the United States despite similar overall survival in the modalities, and recent incentives to expand these modalities. Although the absolute number of patients using home modalities has grown, the proportion compared to in-center hemodialysis (ICHD) continues to remain quite low. Well known barriers to home dialysis utilization exist, and an organized and team-based approach is required to overcome these barriers. Herein, we describe our efforts at growing our home dialysis program at a large academic medical center, with the proportion of home dialysis patients growing from 12% to 21% over the past 9 years. We prioritized individualized education for patients and better training for physicians, with the help of existing resources, aimed at better utilization of home modalities; an example includes dedicated dialysis education classes taught twice monthly by an experienced nurse practitioner, as well as the utilization of the dialysis educator from a dialysis provider for inpatient education of patients with CKD. The nephrology fellowship curriculum was restructured with emphasis on home modalities, and participation in annual home dialysis conferences has been encouraged. For timely placement and troubleshooting of access for dialysis, we followed a complementary team approach using surgeons and interventional radiologists and nephrologists, driven by a standardized protocol developed at UAB, and comanaged by our access coordinators. A team-based approach, with emphasis on staff engagement and leadership opportunities for dialysis nurses as well as collaborative efforts from a team of clinical nephrologists and the dialysis provider helped maintain efficiency, kindle growth, and provide consistently high-quality clinical care in the home program. Lastly, efforts at reducing burden of disease such as decreased number of monthly visits as well as using innovative strategies, such as telenephrology and assisted PD and HHD, were instrumental in reducing attrition.10.34067/KID.0000662019Fri, 01 May 2020 01:31:00 GMT-07:00Setting Up and Expanding a Home Dialysis Program: Is There a Recipe for Success?Home dialysis modalities remain significantly underused in the United States despite similar overall survival in the modalities, and recent incentives to expand these modalities. Although the absolute number of patients using home modalities has grown, the proportion compared to in-center hemodialysis (ICHD) continues to remain quite low. Well known barriers to home dialysis utilization exist, and an organized and team-based approach is required to overcome these barriers. Herein, we describe our efforts at growing our home dialysis program at a large academic medical center, with the proportion of home dialysis patients growing from 12% to 21% over the past 9 years. We prioritized individualized education for patients and better training for physicians, with the help of existing resources, aimed at better utilization of home modalities; an example includes dedicated dialysis education classes taught twice monthly by an experienced nurse practitioner, as well as the utilization of the dialysis educator from a dialysis provider for inpatient education of patients with CKD. The nephrology fellowship curriculum was restructured with emphasis on home modalities, and participation in annual home dialysis conferences has been encouraged. For timely placement and troubleshooting of access for dialysis, we followed a complementary team approach using surgeons and interventional radiologists and nephrologists, driven by a standardized protocol developed at UAB, and comanaged by our access coordinators. A team-based approach, with emphasis on staff engagement and leadership opportunities for dialysis nurses as well as collaborative efforts from a team of clinical nephrologists and the dialysis provider helped maintain efficiency, kindle growth, and provide consistently high-quality clinical care in the home program. Lastly, efforts at reducing burden of disease such as decreased number of monthly visits as well as using innovative strategies, such as telenephrology and assisted PD and HHD, were instrumental in reducing attrition.Ahmad, MasoodWallace, Eric L.Jain, Gaurav2020-05-01T13:31:00-07:00doi:10.34067/KID.0000662019hwp:resource-id:kidney360;1/6/569American Society of NephrologyCopyright © 2020 by the American Society of NephrologyKidney360dialysis, barriers to home dialysis, home dialysis, home dialysis academy, home hemodialysis, modality education, peritoneal dialysis, telenephrology, urgent peritoneal dialysisReview ArticleReview Articlereview-article20202020-06-2510.34067/KID.00006620192641-76502020-05-01T13:31:00-07:002020-06-25Kidney360Review Article16569579Kidney Health Initiative Roadmap for Kidney Replacement Therapy10.2215/CJN.15031219Tue, 14 Apr 2020 10:16:18 GMT-07:00Kidney Health Initiative Roadmap for Kidney Replacement TherapyGee, Patrick O.2020-04-14T10:16:18-07:00doi:10.2215/CJN.15031219hwp:resource-id:clinjasn;15/5/585American Society of NephrologyCopyright © 2020 by the American Society of NephrologyClinical Journal of the American Society of NephrologyRenal Replacement Therapy, Acute Kidney InjuryPatient VoicePatient Voiceresearch-article20202020-05-07May 07, 202010.2215/CJN.150312191555-90411555-905X2020-04-14T10:16:18-07:002020-05-07Clinical Journal of the American Society of NephrologyPatient Voice155585586Economic Evaluation of Extending Medicare Immunosuppressive Drug Coverage for Kidney Transplant Recipients in the Current Era10.1681/ASN.2019070646Fri, 08 Nov 2019 07:45:23 GMT-08:00Economic Evaluation of Extending Medicare Immunosuppressive Drug Coverage for Kidney Transplant Recipients in the Current EraKadatz, MatthewGill, John S.Gill, JagbirFormica, Richard N.Klarenbach, Scott2019-11-08T07:45:23-08:00doi:10.1681/ASN.2019070646hwp:resource-id:jnephrol;31/1/218American Society of NephrologyCopyright © 2020 by the American Society of NephrologyJournal of the American Society of Nephrologykidney transplantation, Economic Analysis, transplant outcomes, MedicareClinical ResearchClinical Researchresearch-article20202020-01-01January 202010.1681/ASN.20190706461046-66731533-34502019-11-08T07:45:23-08:002020-01Journal of the American Society of NephrologyClinical Research311218228Public Policy and Patient Choice of Dialysis Modality10.2215/CJN.12151019Thu, 21 Nov 2019 08:40:20 GMT-08:00Public Policy and Patient Choice of Dialysis ModalityHartwell, Lori2019-11-21T08:40:20-08:00doi:10.2215/CJN.12151019hwp:resource-id:clinjasn;14/12/1677American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologypublic policy, peri, hemodialysis, humans, United States, Medicaid, nephrologists, kidney transplantation, motivation, dialysis, vulnerable populations, goals, quality of life, respite care, home hemodialysis, Medicare, renal insufficiency, renal dialysis, health care costs, fear, anxiety, abdomen, homeless persons, chronic renal insufficiency, quality of health carePatient VoicePatient Voiceeditorial20192019-12-06December 06, 201910.2215/CJN.121510191555-90411555-905X2019-11-21T08:40:20-08:002019-12-06Clinical Journal of the American Society of NephrologyPatient Voice1412121677176316781772Advancing American Kidney Health10.2215/CJN.10280819Fri, 08 Nov 2019 07:28:00 GMT-08:00Advancing American Kidney HealthNissenson, Allen R.Becker, Bryan N.2019-11-08T07:28:00-08:00doi:10.2215/CJN.10280819hwp:resource-id:clinjasn;14/12/1808American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, dialysis, kidney transplantation, kidney transplant, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.102808191555-90411555-905X2019-11-08T07:28:00-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141218081810A Patient’s Perspective on Advancing American Kidney Health Initiative10.2215/CJN.10560919Wed, 06 Nov 2019 10:55:50 GMT-08:00A Patient’s Perspective on Advancing American Kidney Health InitiativeKnight, Richard2019-11-06T10:55:50-08:00doi:10.2215/CJN.10560919hwp:resource-id:clinjasn;14/12/1795American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, dialysis access, end stage kidney disease, kidney disease, kidney transplantation, patient, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.105609191555-90411555-905X2019-11-06T10:55:50-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217951797A Call to Action for the Kidney Community10.2215/CJN.10470919Thu, 07 Nov 2019 05:56:48 GMT-08:00A Call to Action for the Kidney CommunityBieber, Scott D.Gadegbeku, Crystal A.2019-11-07T05:56:48-08:00doi:10.2215/CJN.10470919hwp:resource-id:clinjasn;14/12/1799American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologychronic kidney disease, end-stage renal disease, kidney transplantation, health policy, kidney health, United States, nephrologists, kidney, learning, nephrology, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.104709191555-90411555-905X2019-11-07T05:56:48-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217991801Advancing American Kidney Health10.2215/CJN.10370819Fri, 08 Nov 2019 07:28:00 GMT-08:00Advancing American Kidney HealthKossmann, Robert J.Weinhandl, Eric D.2019-11-08T07:28:00-08:00doi:10.2215/CJN.10370819hwp:resource-id:clinjasn;14/12/1811American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States, kidney, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.103708191555-90411555-905X2019-11-08T07:28:00-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141218111813Transforming Care for Patients and Providers10.2215/CJN.10390919Fri, 08 Nov 2019 07:28:00 GMT-08:00Transforming Care for Patients and ProvidersWatnick, SuzanneSilberzweig, Jeffrey2019-11-08T07:28:00-08:00doi:10.2215/CJN.10390919hwp:resource-id:clinjasn;14/12/1805American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologydialysis, chronic kidney disease, transplantation, peritoneal dialysis, end-stage renal disease, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.103909191555-90411555-905X2019-11-08T07:28:00-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141218051807A Vision for Advancing American Kidney Health10.2215/CJN.10460919Tue, 05 Nov 2019 07:41:47 GMT-08:00A Vision for Advancing American Kidney HealthPatel, SandeepBoehler, AdamUehlecke, Nicholas2019-11-05T07:41:47-08:00doi:10.2215/CJN.10460919hwp:resource-id:clinjasn;14/12/1789American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of NephrologyAAKHI, Department of Health and Human ServicesPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.104609191555-90411555-905X2019-11-05T07:41:47-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217891791July 10, 2019, A Day to Be Remembered10.2215/CJN.10440919Wed, 06 Nov 2019 10:55:50 GMT-08:00July 10, 2019, A Day to Be RememberedScott, Nancy2019-11-06T10:55:50-08:00doi:10.2215/CJN.10440919hwp:resource-id:clinjasn;14/12/1798American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of Nephrologykidney transplant, kidney transplantation, transplant patients, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.104409191555-90411555-905X2019-11-06T10:55:50-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217981798Advancing American Kidney Health10.2215/CJN.11840919Tue, 05 Nov 2019 07:41:48 GMT-08:00Advancing American Kidney HealthMehrotra, Rajnish2019-11-05T07:41:48-08:00doi:10.2215/CJN.11840919hwp:resource-id:clinjasn;14/12/1788American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of NephrologyAAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.118409191555-90411555-905X2019-11-05T07:41:48-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217881788Preparing the Nephrology Workforce for the Transformation to Value-Based Kidney Care10.2215/CJN.08080719Thu, 07 Nov 2019 05:56:48 GMT-08:00Preparing the Nephrology Workforce for the Transformation to Value-Based Kidney CareTummalapalli, Sri LekhaPeralta, Carmen A.2019-11-07T05:56:48-08:00doi:10.2215/CJN.08080719hwp:resource-id:clinjasn;14/12/1802American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States, nephrology, needs assessment, kidney, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.080807191555-90411555-905X2019-11-07T05:56:48-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141218021804Winning the War on Kidney Disease10.2215/CJN.10180819Tue, 05 Nov 2019 07:41:48 GMT-08:00Winning the War on Kidney DiseaseRosenberg, Mark E.Ibrahim, Tod2019-11-05T07:41:48-08:00doi:10.2215/CJN.10180819hwp:resource-id:clinjasn;14/12/1792American Society of NephrologyCopyright © 2019 by the American Society of NephrologyClinical Journal of the American Society of NephrologyUnited States, kidney diseases, nephrology, societies, AAKHIPerspectivesPerspectivesresearch-article20192019-12-06December 06, 201910.2215/CJN.101808191555-90411555-905X2019-11-05T07:41:48-08:002019-12-06Clinical Journal of the American Society of NephrologyPerspectives141217921794Value-Based Kidney Care: Aligning Metrics and Incentives to Improve the Health of People with Kidney Disease10.1681/ASN.2019101007Thu, 14 Nov 2019 06:44:31 GMT-08:00Value-Based Kidney Care: Aligning Metrics and Incentives to Improve the Health of People with Kidney DiseaseGarimella, Pranav S.Weiner, Daniel E.2019-11-14T06:44:31-08:00doi:10.1681/ASN.2019101007hwp:resource-id:jnephrol;30/12/2282American Society of NephrologyCopyright © 2019 by the American Society of NephrologyJournal of the American Society of Nephrologychronic kidney disease, end stage kidney disease, kidney diseaseUp Front MattersEditorialsUp Front MattersEditorialseditorial20192019-12-01December 201910.1681/ASN.20191010071046-66731533-34502019-11-14T06:44:31-08:002019-12Journal of the American Society of NephrologyUp Front Matters3012122282246422842472